AI Summary & Key Takeaways
AI InsightOur all data were compatible with the literature.
📌 3 Key Takeaways
Abstract
Objective: Autoimmune bullous disorders (ABD), which occur on the genetic background and characterized with vesicles and bullae, have high morbidity and mortality rates epidemiologically. They exhibit distinctive features in terms of demographic and clinical characteristics and display diagnostic and therapeutic difficulties. Our aim to evaluate and manifest the clinical and demographic features of the inpatients with ABD, between Jan 1997 and Jan 2007 ;to document data and review the literature. Methods and Materials: The medical records of the patients with ABD admitting to our dermatology department between Jan 1997 and Jan 2007 were evaluated. Demographic and clinical features including anatomic localisation of the lesions, associated disorders, complications were recorded by microsoft access database software. Results and Conclusion: 79 patients with ABD were enrolled to the study, (mean age: 52,96 and female/male ratio was 50129.) The most frequently seen ABD was pemphigus vulgaris (PV %49,36) and bullous pemhigoid (BP, %32,91) and pemphigus herpetiformis and linear IgA bullous disease were the least frequent OBD with a ratio of %1,26. The patients with PV had longest duration of hospitalization with a mean duration of 34,2 days The lesions were most frequently seen on the back region of trunk (%60). Oral mucosal lesions were most frequently seen on the patients with PV .The OBD with the longest period before the diagnosis was pemphigus vegetans. Our all data were compatible with the literature.
Özet
Amaç: Otoimmün büllü dermatozlar (OBD) genetik zeminde gelişen, vezikül ve bililerle seyreden , morbidite ve mortalitesi yüksek hastalıklardır. Bu dermatozlar, demografik ve klinik özellikler açısından farklılıklar göstermekte, tanısal ve tedavi zorluklan yaratmaktadır. Amacımız OBD'li hastalarda klinik, demografik özelliklerin araştırılması ve bulguların belgelendirilmesidir. Gereç ve Yöntem: Ocak 1997 -Ocak 2007 tarihleri arasında kliniğimizde yatarak tedavi gören OBD'li hastaların epikriz ve genel arşiv dosyaları incelendi. Demografik özellikler, klinik bulgular kaydedilerek literatür gözden geçirildi. Bulgular: Çalışmaya toplam 79 OBD hastası alındı, (yaş ortalaması 52.96, kadınlerkek, 50129) .En sık OBD Pemfigus Vulgaris (PV, %49J6), en nadir OBD . Pemfıgus Herpetiformis ve Lineer IgA dermatozu (%1,26) idi. PV hastaları ortalama 34,2 günle en uzun yatış süresine sahipti. En sık anatomik tutulum yeri gövde arka yüz lokalizasyonuydu. (% 60). Oral mukozal lezyonlar en sık PV de görüldü.. Tanı almadan önce ortalama yakınma süresi en uzun olan hastalık, 89,16 ay ile Pemfigus Vejetans idi. Sonuçlar: Bulgularımız literatürle benzerlik göstermekteydi.