Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2014 / Cilt: 48 - Sayı: 4

The nephrotic syndrome with secondary syphilis

Nefrotik Sendromla Gelen Sekonder Sifiliz

Pages
332–334
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report a VDRL and TPHA positive patient who presented with nephrotic syndrome whose renal biopsy demonstrated stage one membraneous glomerulopathy.

📌 3 Key Takeaways

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Objective & Hypothesis:Syphilis is a sexually transmitted disease which is caused by a spirochete called T. pallidum.
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Key Findings & Data:It is known as 'the great simulator', owing to its range of clinical presentations.The relationship between syphilis and renal disease has been recognized for more than 100 years.
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Conclusion & Impact:We report a VDRL and TPHA positive patient who presented with nephrotic syndrome whose renal biopsy demonstrated stage one membraneous glomerulopathy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Syphilis is a sexually transmitted disease which is caused by a spirochete called T. pallidum. It is known as 'the great simulator', owing to its range of clinical presentations.The relationship between syphilis and renal disease has been recognized for more than 100 years. Proteinuria is the most common clinical manifestation. Membranous glomerulonephritis, rapidly progressive glomerulonephritis, diffuse endocapillary glomerulonephritis with or without extracapillary formation or minimal change glomerulonephritis have been described in association with syphilis. The definitive diagnosis is confirmed by renal biopsy. We report a VDRL and TPHA positive patient who presented with nephrotic syndrome whose renal biopsy demonstrated stage one membraneous glomerulopathy.

Özet

Sifiliz, T. pallidum adı verilen spiroket etkenli cinsel yolla bulaşan bir hastalıktır. Gösterdiği klinik tablolara bağlı olarak 'büyük simülatör' olarak da tanınmaktadır. Sifiliz ve renal hastalıklar arasındaki ilişki yüzyıldan uzun bir süredir bilinmektedir. Proteinüri en yaygın görülen klinik göstergedir. Sifilizle ilişkili olarak membranöz glomerülonefrit, hızlı ilerleyen glomerülonefrit, ekstrakapiller oluşumlu ya da oluşumsuz diffüz endokapiller glomerülonefrit ve minimal değişim glomerülonefrit tanımlanmıştır. Kesin tanı böbrek biyopsisiyle konulmaktadır. VDRL ve TPHA pozitif olup nefrotik sendromla başvuran ve yapılan böbrek biyopsisinde evre 1 membranöz glomerülopati saptanan bir olgu sunuyoruz.

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Cite This Article

BÖYÜK, B., ALTAY, M., ATALAY, H., DEĞİRMENCİOĞLU, Ş., ÇELEBİ, A., EKİZOĞLU, İ., BOZKURTGİL, N. (2014). The nephrotic syndrome with secondary syphilis. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 48 - Sayı: 4, 332–334. https://ajindex.com/articles/363799

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