Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2018 / Cilt: 52 - Sayı: 3

Can TG/HDL Ratio be an Accurate Predictor in the Determination of the Risk of Cerebrovascular Events in Youngsters?

Pages
199–203
DOI
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⚡ TL;DR(Too Long; Didn't Read)

As the TG/HDL ratio has proven to be a highly significantindependent prognostic predictor of stroke, it should be calculated in young patients with ischemic stroke.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: There is good evidence that shows that modification of modifiable risk factor will reduce the risk of stroke.
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Key Findings & Data:Studies have shown that nontraditional serum lipid variables may be better predictors of vascularrisk rather than others.The objective of the present study was to assess the relationships of traditional and nontraditional serum lipid measurementsbetween young and elder patients with stroke and healthy young adults.Methods: One hundred twelve young patients with ischemic stroke, 113 healthy adults, and 110 patients with ischemic strokeaged >45 years were included in the study.
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Conclusion & Impact:As the TG/HDL ratio has proven to be a highly significantindependent prognostic predictor of stroke, it should be calculated in young patients with ischemic stroke.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objectives: There is good evidence that shows that modification of modifiable risk factor will reduce the risk of stroke. Hyperlipidemiais one of these risk factors. Studies have shown that nontraditional serum lipid variables may be better predictors of vascularrisk rather than others.The objective of the present study was to assess the relationships of traditional and nontraditional serum lipid measurementsbetween young and elder patients with stroke and healthy young adults.Methods: One hundred twelve young patients with ischemic stroke, 113 healthy adults, and 110 patients with ischemic strokeaged >45 years were included in the study. Laboratory tests for total cholesterol (TC), its fractions, and triglycerides (TGs) wereperformed using standard techniques, and we computed four nontraditional lipid variables.Statistical analyses were performed using chi-square test, Student's t-test, and SPSS version 16.0 software. A p value of 45 years was 69.53±12.34 years. There were 63 male and 47 female patients.Measurements of lipid parameters were as follows: LDL 125.18±35.97 mg/dl, HDL 41.47±14.16 mg/dl, TG 117.53±59.03 mg/dl, TC190.16±42.96 mg/dl, LDL/HDL 3.32±1.55, TG/HDL 3.46±3.43, and TC/HDL 5.01±2.08. TG level and TG/HDL ratio were significantlyhigher in young patients with stroke than in older cases.Conclusion: All lipid measurements were significantly higher in young patients with ischemic stroke than in young healthy adults.TG level and TG/HDL ratio were significantly higher in male than in female patients. In addition, TG level and TG/HDL ratio weresignificantly higher in young patients with stroke than in older cases. As the TG/HDL ratio has proven to be a highly significantindependent prognostic predictor of stroke, it should be calculated in young patients with ischemic stroke.

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Cite This Article

ÇOBAN, E. K. (2018). Can TG/HDL Ratio be an Accurate Predictor in the Determination of the Risk of Cerebrovascular Events in Youngsters?. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 52 - Sayı: 3, 199–203. https://ajindex.com/articles/363710

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References (9)

  1. Allen CMC, Lueck CJ, Dennis M. Cerebrovascular Diseases. In: Doon NA, College NR, Walker BR, Hunter JAA, editors. Davidson’s principles and Practice of Medicine. 20th edition, Churchill Livingstone Elsevier, Philadelphia, 2006. p. 1200–11.
  2. Sreedhar K, Srikant B, Joshi L, Usha G. Lipid profile in non-diabetic stroke-a study of 100 cases. J Assoc Physicians India 2010;58:547–51.
  3. Bittner V, Hardison R, Kelsey SF, Weiner BH, Jacobs AK, Sopko G; Bypass Angioplasty Revascularization Investigation. Non-highdensity lipoprotein cholesterol levels predict five-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI). Circulation 2002;106:2537–42.
  4. Ridker PM, Rifai N, Cook NR, Bradwin G, Buring JE. Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women. JAMA 2005;294:326–33.
  5. Meschia JF, Bushnell C, Boden-Albala B, Braun LT, Bravata DM, Chaturvedi S, et al; American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Functional Genomics and Translational Biology; Council on Hypertension. Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2014;45:3754–832.
  6. Khan H, Afridi AK, Saadia A. A hospital based study on stratification of risk factors of stroke in Peshawar. Pak J Med Sci 2006;22:304–7. Tanveer A. Localization and management in Cerebrovascular accident: a comparison of clinical assessment versus C.T scan [Dissertation]. College of Physicians & Surgeons Pakistan: Karachi; 1996.
  7. Mahmood A, Sharif MA, Khan MN, Ali UZ. Comparison of serum lipid profile in ischaemic and haemorrhagic stroke. J Coll Physicians Surg Pak 2010;20:317–20. Enar R. Ateroskleroz; İ.Ü. Cerrahpaşa Tıp Fakültesi Sürekli Tıp Eğitimi Etkinlikleri. Koroner, Serebral, Periferik Arter Tutulumu Sempozyum Dizisi No: 52: 2006; p. 9–27.
  8. Putaala J, Haapaniemi E, Metso AJ, Metso TM, Artto V, Kaste M, et al. Recurrent ischemic events in young adults after first-ever ischemic stroke. Ann Neurol 2010;68:661–71.
  9. Nirmala AC, Mamatha TN, Priya Shree R, Avinash BH. Study of lipid profile in non-diabetic stroke in young. Sch J App Med Sci 2015;3:1259–65. Miller NE. Associations of high-density lipoprotein subclasses and apolipoproteins with ischemic heart disease and coronary atherosclerosis. Am Heart J 1987;113:589–97. Gazi