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Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2005 / Cilt: 39 - Sayı: 1

The results of single dose betametasone application in preterm labours and its effectivity

Preterm eylemlerde tek doz betametazon uygulamasının sonuçları ve etki süresi

Suna ÖZDEMİR
Birgül GÜRASLAN
Özgür AKBAYIR
Hakan GÜRASLAN
Nurdan NURULLAHOĞLU
S. Nihan KARAKAYA
Onur EROL
Ahmet GÜLKILIK
Pages
47–55
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: There was no significant statistical difference between the groups about the most frequently observed neonatal complications.(Rrespiratory distress syndrome (RDS), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), sepsis, hyperbilirubinemia) Conclusions: There was no significant statistical difference between the groups about the most frequently observed neonatal complications

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study we have researched, perinatal effects of the duration of the time period between the single dose antenatal steroid application and the labour.
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Key Findings & Data:By matching the first 7 days data and the data between days 8-T4 we intended to achieve whether there wgs a duration of steroid effect one week later after the steroid administration.
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Conclusion & Impact:Results: There was no significant statistical difference between the groups about the most frequently observed neonatal complications.(Rrespiratory distress syndrome (RDS), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), sepsis, hyperbilirubinemia) Conclusions: There was no significant statistical difference between the groups about the most frequently observed neonatal complications
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Geriyedönük çalışma · Obstetrik doğum · prematür

Abstract

Objective: In this study we have researched, perinatal effects of the duration of the time period between the single dose antenatal steroid application and the labour. By matching the first 7 days data and the data between days 8-T4 we intended to achieve whether there wgs a duration of steroid effect one week later after the steroid administration. Study Design: We included subjects who attended to our perinatology clinic and gave birth between 28th and 34th weeks of gestational age. The data of the subjects and the babies given birth were retrospectively evaluated. Eighty-two subject who filled the study criteria were included to the study. Fifty-nine pregnant women who completed their hetamethasone protocol and gave birth between 1-7 days, formed the group I. the rest 23 pregnant women who gave birth between days 8-14 formed the group 2. Results: There was no significant statistical difference between the groups about the most frequently observed neonatal complications.(Rrespiratory distress syndrome (RDS), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), sepsis, hyperbilirubinemia) Conclusions: There was no significant statistical difference between the groups about the most frequently observed neonatal complications

Özet

Amaç: Bu çalışmada, tek doz antenatal steroid uygulaması ile doğum arasındaki sürenin uzunluğunun perinatal sonuçlara etkisini araştırdık. İlk 7 gün sonuçları ile 8-14 gün sonuçlarını karşılaştırarak steroid etkisinin bir hafta sonra devam edip etmediğini saptamayı amaçladık. Gereç ve Yöntem: Çalışmaya, perinatoloji kliniğimize preterm eylem nedeni ile başvuran 28 ile 34. gebelik haftalar arasında doğum yapmış 82 olgu alındı. Olgulara ait bilgiler ve doğan bebeklerin antenatal izlem dosyaları retrospektif olarak değerlendirildi. Betametazon uygulama protokolünü tamamlamış 1-7 gün arasında doğum yapmış 59 gebe (Grup I), 8-14 gün arasında doğum yapmış 23 gebe (Grup II) sap¬tandı. Bulgular: Gruplar arasında en sık rastlanan neonatal komplikasyonlar (Respiratuar distres sendromu (RDS), intraventriküler kanama (İVK), nekrotizan enterekolit (NEK), sepsis, hiperhiliruhinemi, açısından yapılan istatistiksel analizlerde anlamlı bir fark saptanmadı. Sonuç: Gruplar arasında en sık rastlanan neonatal komplikasyonlar açısından istatistiksel olarak anlamlı fark saptamadık

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Cite This Article

ÖZDEMİR, S., GÜRASLAN, B., AKBAYIR, Ö., GÜRASLAN, H., NURULLAHOĞLU, N., KARAKAYA, S. N., EROL, O., GÜLKILIK, A. (2005). The results of single dose betametasone application in preterm labours and its effectivity. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 39 - Sayı: 1, 47–55. https://ajindex.com/articles/363592

References (14)

  1. Cresy RK, İams JD: Preterm labor and delivery. İn creasy RK, Resnik R(eds) Maternal fetal medicine. Principles anil practise. 4tli edition. Philadelphia, W.B. Saunders company 1999; 498-531
  2. Rush RW, Keirse MJNC, Howat P, et al: Contribution of preterm delivery lo perinatal mortality. Br Med J 1976; 2: 965
  3. Antenatal Fetal Assesment. Devoe LD. Clinics İN Perinatology. W.B. Saunders. 1994 4. Liggins GC Preterm delivery of fetal lambs infused with glucocorticoids.). Endocrinol. 1969; 45: 515-23
  4. NIH Consensus Conference. Effect of corticosteroids for fetai maturation on perinatal outcomes. JAMA 1995; 273; 413-18
  5. Antenatal corticosteroids revisited: repeat courses. NIH Consensus Statement 2000; 17(2): 1-10 7. Silver R, Vyskocil C, Solomon S. Randomized trial of antenatal dexamethasone in, surfactant treated infants deli¬vered before 30 weeks gestation. Obstetrics& Gyneco¬logy. 1996; 87; 683-91 8. Ballard R, Ballard P, Creasy R. Respiratory disease in very low birth weight infants after prenatal thyrotropin releasing hormone and glucocorticoid. Lancet 1992; 339: 510-15
  6. Ikegami M, Polk DH, Jobe AH, Nevvham J, Sly P, Kohan R, et al. Effect of interval from fetal corticosteroid treat¬ment to delivery on postnatal lung function of preterm lambs. J App Physiol 1996; 80: 591-7
  7. Whilelaw A, Tlıoıesan M. Antenatal steroids and the developing brain. Arc Dis Child Neonatal Ed 2000; 83: 154-157
  8. Berks JB, Mulder EH, Visser GH. The ciTects ol'maternal betamethasone administration on the i'etus. Br J Obstet Gynecol 1995; 102:40-46
  9. Harding JE, Pang J, Knight DB, Liggins GC. Do antenatal corticosteroids help in the selling ol" preterm rupture of membranes? Am J Obstet Gynecol 2001; 1 84: 131- 139
  10. Dawes GS, Sera SV, Mauklen M. Dexamethason and fetal heart variation. Br J Obstet Gynecol 1994; 101: 675- 679
  11. Burke It G, Bauer CR, Morrison JC, Curet LB. Effect of prenatal dexamethasone administration on prevention of RDS in twin pregnancies. J Perinatal 1986; 6: 304-308
  12. Banks BA, Maconess G, Cnaan A, et al. Multiple courses of antenatal corticosteroids arc associated with early se¬vere lung disease in preterm neonates. J Perinatol 2002; 22: 101-107
  13. Walfisch A, Mallak M, Mazor M. Multipl courses of antenat sterods: risks and benefits. ObsLet Gynecol 2001; 98: 491- 497
  14. McElralh TF, Norwilz Er, Nour N, Robinson JN. Contemporary trends in the management of delivery at 23 weeks gestation. Am J Perinalol. 2002; 19:9-15. 18.