SavedAdd your journal

Journals / Şişli Etfal Hastanesi Tıp Bülteni / 2011 / Cilt: 45 - Sayı: 4

Iatrogenic Cushing syndrome due to topically used steroid; case report

Topikal steroid kullanımına bağlı gelişen iyatrojenik Cushing sendromu; olgu sunumu

Meltem UĞRAŞ
Altuğ Tolga ŞEN
Özlem GÜRAKSIN
Faruk ALPAY
Pages
138–141
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we reported a 7 months old girl with Cushing syndrome that developed after the prolonged use of pomades containing topical corticosteroid and so we emphasized to be cautious about the use topical corticosteroids.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Diaper dermatitis and atopic dermatitis are frequent problems of infants in which pomades containing corticosteroids are used for the therapy.
📊
Key Findings & Data:Prolonged use of potent corticosteroids supress adrenal functions and iatrogenic Cushing syndrome may develop especially in infants who uses topical corticosteroids.
💡
Conclusion & Impact:Here we reported a 7 months old girl with Cushing syndrome that developed after the prolonged use of pomades containing topical corticosteroid and so we emphasized to be cautious about the use topical corticosteroids.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Diaper dermatitis and atopic dermatitis are frequent problems of infants in which pomades containing corticosteroids are used for the therapy. Prolonged use of potent corticosteroids supress adrenal functions and iatrogenic Cushing syndrome may develop especially in infants who uses topical corticosteroids. Here we reported a 7 months old girl with Cushing syndrome that developed after the prolonged use of pomades containing topical corticosteroid and so we emphasized to be cautious about the use topical corticosteroids.

Özet

Diaper dermatit ve atopik dermatit bebeklik döneminde sık görülen problemlerdir ve tedavilerinde steroid içeren merhemler kullanılmaktadır. Potent steroid içeren preparatların gereğinden uzun süreli kullanımı sonucunda adrenal bezin fonksiyonları baskılanabilmekte ve özellikle süt çocuğu döneminde topikal steroidlerle iyatrojenik Cushing sendromu gelişebilmektedir. Burada kortikosteroid içeren merhemlerin uzun süreli kullanımı sonrasında Cushing sendromu gelişen 7 aylık kız olgunun sunumu yapılarak topikal kortikosteroid kullanımında dikkatli olunması gerektiği vurgulanmıştır.

🔖

Cite This Article

UĞRAŞ, M., ŞEN, A. T., GÜRAKSIN, Ö., ALPAY, F. (2011). Iatrogenic Cushing syndrome due to topically used steroid; case report. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 45 - Sayı: 4, 138–141. https://ajindex.com/articles/363506

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Kandemir N. Adrenal Hastalıklar. Günöz H, Öcal G, Yordam N, Kurtoğlu S (Editörler). Pediatrik Endokrinoloji, Pediatrik Endokrinoloji ve Oksoloji Derneği Yayınları: 1, pp: 361-414
  2. Miller WL. The adrenal cortex and its disorders. In: Brook CGD, Hindmarsh PC, eds. Clinical pediatric endocrinology, 4th ed. Oxford: Blackwell Science, 2001:321-76
  3. Root AW, Shulman DI. Clinical Adrenal Disorders. In: Pescovitz OH, Eugster EA, editors, Pediatric Endocrinology. Philadelphia: Lippincott Willams and Wilkins 2004. pp: 568-600
  4. Abma EM, Blanken R, De Heide LJ. Cushing’s syndrome caused by topical steroid therapy for psoriasis. Neth J Med. 2002; 60: 148-50
  5. Halverstam CP, Vachharajani A, Mallory SB. Cushing syndrome from percutaneous absorption of 1% hydrocortisone oinment in Netherton syndrome. Pediatr Dermatol 2007; 24: 42-5
  6. Allen DB. Safety of inhaled corticosteroids in children. Pediatr Pulmonol 2002; 33:208-20
  7. Perry RJ, Findlay CA, Donaldson MDC. Cushing’s syndrome, growth impairment, and occult adrenal suppression associated with intranasal steroids. Arch Dis Child. 2002; 87:45-8
  8. Ozerdem U, Levi L, Cheng L, Song MK, Scher C, Freeman WR. Systemic toxicity of topical and periocular corticosteroid therapy in an 11-year-old male with posterior uveitis. Am J Ophthalmol 2000; 130: 240-1
  9. Teelucksingh S, Balkaran B, Ganeshmoorthi A, Arthur P. Prolonged childhood Cushing’s syndrome secondary to intralesional triamcinolone acetonide. Ann Trop Paediatr. 2002; 22: 89-91
  10. Steelman J, Kappy M. Adrenal suppression and growth retardation from ocular corticosteroids. J Pediatr Ophthalmol Strabismus. 2001; 38: 177-8
  11. Migeon CJ. Adrenal cortex. In: Lifshitz F (ed). Pediatric Endocrinology (3rd ed., revised and expanded). New York: Markel Dekker, Inc, 2003: 147-74
  12. Magiakou MA, Mastorakos G, Oldfield EH, Gomez MT, Doppman JL, Cutler GB Jr, et al. Cushing’s syndrome in children and adolescents. Presentation, diagnosis and therapy. New Eng J Med 1994; 331: 629-39
  13. Chamberlin P, Meyer WJ. Management of pituiary-adrenal suppression secondary to corticosteroid therapy. Pediatrics 1981; 67: 245-51
  14. Park YJ, Park KS, Kim JH, Shin CS, Kim SY, Lee HK. Reproductibility of the cortisol response to stimulation with the low dose (1 mg) of ACTH. Clin Endocrinol 1999; 51: 153-8
  15. Harper J. Topical corticosteroids for skin disorders in infants and children. Drugs 1988; 36: 34-7
  16. Turpeinen M, Salo OP, Leisti S. Effect of percutaneous absorptio