Journals / Tanısal ve Girişimsel Radyoloji (Yeni Adı: Dİagnostic & Intervent. Radiol) / 2004 / Cilt: 10 - Sayı: 2

Biochemical and immunological effects of ionizing radiation in radiology staff members

İyonizan radyasyonun radyoloji çalışanlarının bağışıklık düzeyleri ve kan biyokimyası üzerine etkileri

Pages
97–102
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Since the staff members of department of radiology are vulnerable to the side effects in parallel to the dose of radiation being exposed, we think that in addition to avoiding radiation as much as possible, they should have periodical blood biochemistry and immune function tests.

📌 3 Key Takeaways

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Objective & Hypothesis:PURPOSE: This study aimed to investigate the influence of occupational exposures to long term low-dose ionizing radiation on blood biochemistry and immunity levels of the radiology staff.
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Key Findings & Data:MATERIALS AND METHODS: Fifty-one subjects, aged between 21-57 years (30.06±7.02 years), working in the department of radiology were enrolled to this study.
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Conclusion & Impact:Since the staff members of department of radiology are vulnerable to the side effects in parallel to the dose of radiation being exposed, we think that in addition to avoiding radiation as much as possible, they should have periodical blood biochemistry and immune function tests.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Bağışıklık · Tıbbi personel · Radyasyon

Abstract

PURPOSE: This study aimed to investigate the influence of occupational exposures to long term low-dose ionizing radiation on blood biochemistry and immunity levels of the radiology staff. MATERIALS AND METHODS: Fifty-one subjects, aged between 21-57 years (30.06±7.02 years), working in the department of radiology were enrolled to this study. Twenty-five subjects (49.1%) were female and 26 (50.9%) were male. Control group consisted of 40 healthy non-smoking subjects aged between 20-60 years (mean 31.5±5.75) who had never been exposed to radiation; 19 (47.5%) of these were female and 21 (52.5%) male. Venous blood samples were obtained from the radiology staff and control group and immunological and biochemical analysis of samples were performed. RESULTS: CD4+ T-lymphocyte ratio, and serum total IgA, IgG, IgM and C3, C4 levels were lower in the radiology staff compared to the controls. Serum triglycerides and paraoxonase activities were increased in the radiology staff (p<0.05). CONCLUSION: In radiology workers exposed to long-term low-dose ionizing radiation, levels of the CD4+ T lymphocytes, total immun globulins (IgA, IgG, IgM), C3 and C4 levels were lower, while serum trygliceride levels and paraoxonase activities were significantly higher (p<0.05). IgA and IgM levels of smoker radiology workers were significantly lower than non-smoker radiology workers (p<0.05). Since the staff members of department of radiology are vulnerable to the side effects in parallel to the dose of radiation being exposed, we think that in addition to avoiding radiation as much as possible, they should have periodical blood biochemistry and immune function tests.

Özet

AMAÇ Mesleki olarak iyonizan radyasyona uzun süre maruz kalan radyoloji çalışanlarında, uzun süreli düşük doz iyonizan radyasyonun, kan biyokimyası ve immünite düzeylerine etkisinin incelenmesi amaçlandı. GEREÇ VE YÖNTEM Radyodiagnostik Anabilim Dalı personelinden, yaşları 21-57 (30.06±7.02) arasında değişen 25’i (%49.1) kadın ve 26’sı (%50.9) erkek toplam 51 radyoloji çalışanı çalışma kapsamına alındı. Kontrol grubu, herhangi bir şekilde radyasyona maruz kalmamış sigara kullanmayan sağlıklı, yaşları 20-60 (31.5±5.75) arasında değişen 19’u (%47.5) kadın ve 21’i (%52.5) erkek 40 kişiden oluşturuldu. Radyoloji çalışanları ve kontrol grubundaki kişilerin her birinden usulüne göre alınan venöz kan örneklerinden immünolojik ve biyokimyasal analizler yapıldı. BULGULAR Radyoloji çalışanlarında CD4+ T lenfosit oranının, serum total IgA, IgG, IgM düzeyleri ile C3, C4 düzeylerinin kontrol grubuna göre anlamlı düzeyde düşük olduğu, serum trigliserit düzeyleri ve serum paraoksonaz aktivitesinin yükselmiş olduğu saptandı (p<0.05). SONUÇ İyonize radyasyona uzun dönem maruz kalan radyoloji çalışanlarında CD4+ T lenfositleri, total immünglobulinler (IgA, IgG, IgM), C3 ve C4’ün azaldığı, biyokimyasal olarak serum trigliserit düzeyleri ve serum paraoksonaz aktivitesinin anlamlı şekilde yükselmiş olduğu saptandı. Sigara içen radyoloji çalışanlarında IgA ve IgM düzeylerinin sigara içmeyenlere göre anlamlı düzeyde düşük olduğu saptandı (p<0.05). Radyoloji çalışanlarında, etkilendikleri absorbe doza paralel ağırlıkta yan etkiler oluşacağından dolayı, bu kişilerin radyasyondan korunmaya olabildiğince dikkat etmelerinin yanında periyodik olarak, immün fonksiyonlarının değerlendirilmesi ve kan biyokimyası yönünden periyodik olarak izlenmelerinin önemli olacağı kanaatindeyiz.

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Cite This Article

SERHATLIOĞLU, S., OZAN, A. T., GÜRSU, F., GÖDEKMERDAN, A., AYAR, A., OĞUR, E. (2004). Biochemical and immunological effects of ionizing radiation in radiology staff members. Tanısal ve Girişimsel Radyoloji (Yeni Adı: Dİagnostic & Intervent. Radiol), Cilt: 10 - Sayı: 2, 97–102. https://ajindex.com/articles/363197

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