SavedAdd your journal

Journals / The Journal of Pediatric Research / 2017 / Cilt: 4 - Sayı: 4

Oral Ibuprofen Induced Spontaneous Intestinal Perforation in a Preterm Infant

Preterm Bir Bebekte Oral İbuprofenin İndüklediği Spontan İntestinal Perforasyon

Şahin HAMİLCİKAN
Övgü BÜKE
Sultan BENT
Esra ÖZCAN
EMRAH CAN
Pages
242–244
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present a case of a preterm neonate with spontaneous intestinal perforation induced by oral ibuprofen treatment for PDA.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Ibuprofen is often used as an alternative for patent ductus arteriosus (PDA) management in preterm infants.
📊
Key Findings & Data:The reported side effects are fewer than those of indomethacin.
💡
Conclusion & Impact:We present a case of a preterm neonate with spontaneous intestinal perforation induced by oral ibuprofen treatment for PDA.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Ibuprofen is often used as an alternative for patent ductus arteriosus (PDA) management in preterm infants. The reported side effects are fewer than those of indomethacin. Spontaneous intestinal perforation differs from necrotizing enterocolitis, presents an early clinical picture and usually occurs after corticosteroid treatment in preterm infants. We present a case of a preterm neonate with spontaneous intestinal perforation induced by oral ibuprofen treatment for PDA.

Özet

İbuprofen prematüre bebeklerde patent duktus arteriozus (PDA) tedavisinde sıklıkla alternatif olarak kullanılmaktadır. Yan etkileri indometazinden daha az olarak bildirilmektedir. Spontan intestinal perforasyon sıklıkla steroid alımı sonrasında prematüre bebeklerde görülen nekrotizan enterokolitten farklı bir klinik tablodur. Bu olguda PDA tedavisi için oral ibuprofen tedavisi alan prematüre bir yenidoğanda tedavi ile ilişkili spontan intestinal perforasyon olgusu sunuldu.

🔖

Cite This Article

HAMİLCİKAN, Ş., BÜKE, Ö., BENT, S., ÖZCAN, E., CAN, E. (2017). Oral Ibuprofen Induced Spontaneous Intestinal Perforation in a Preterm Infant. The Journal of Pediatric Research, Cilt: 4 - Sayı: 4, 242–244. https://ajindex.com/articles/362975

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Pumberger W, Mayr M, Kohlhauser C, Weninger M. Spontaneous localized intestinal perforation in very-lowbirth-weight infants: a distinct clinical entity different from necrotizing enterocolitis. J Am Coll Surg 2002;195:796-803
  2. Attridge JT, Clark R, Walker MW, Gordon PV. New insights into spontaneous intestinal perforation using a national data set: (1) SIP is associated with early indomethacin exposure. J Perinatol 2006;26:93-9
  3. Guthrie SO, Gordon PV, Thomas V, Thorp JA, Peabody J, Clark RH. Necrotizing enterocolitis among neonates in the United States. J Perinatol 2003;23:278-85
  4. Stark AR, Carlo WA, Tyson JE, et al. Adverse effects of early dexamethasone in extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network. N Engl J Med 2001;344:95- 101
  5. Uceda JE, Laos CA, Kolni HW, Klein AM. Intestinal perforations in infants with a very low birth weight: a disease of increasing survival? J Pediatr Surg 1995;30:1314-6
  6. Alpan G, Eyal F, Vinograd I, et al. Localized intestinal perforations after enteral administration of indomethacin in premature infants. J Pediatr 1985;106:277-81
  7. Kawase Y, Ishii T, Arai H, Uga N. Gastrointestinal perforation in very low-birthweight infants. Pediatr Int 2006;48:599-603
  8. Attridge JT, Clark R, Gordon PV. New insights into spontaneous intestinal perforation using a national data set (3): antenatal steroids have no adverse association with spontaneous intestinal perforation. J Perinatol 2006;26:667- 70
  9. Kelleher J, Salas AA, Bhat R, et al. Prophylactic indomethacin and intestinal perforation in extremely low birth weight infants. Pediatrics 2014;134:1369-77
  10. Attridge JT, Clark R, Walker MW, Gordon PV. New insights into spontaneous intestinal perforation using a national data set: (2) two populations of patients with perforations. J Perinatol 2006;26:185-8
  11. Rao SC, Basani L, Simmer K, Samnakay N, Deshpande G. Peritoneal drainage versus laparotomy as initial surgical treatment for perforated necrotizing enterocolitis or spontaneous intestinal perforation in preterm low birth weight infants. Cochrane Database Syst Rev 2011:CD006182.