Journals / The Journal of Pediatric Research / 2019 / Cilt: 6 - Sayı: 1

A Myasthenia Gravis Case Diagnosed Simultaneously with Diabetic Ketoacidosis

Pages
73–76
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although an autoimmune process may have triggered both autoimmune diseases at the same time in this case, we believe the diabetic ketoacidosis was a triggering factor for the JMG and discuss this association.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Juvenile myasthenia gravis (JMG) is an autoimmune disease caused by antibodies affecting the postsynaptic membrane at the neuromuscular junction.
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Key Findings & Data:Our case is the youngest patient where this association has been reported in the literature and presented at the age of 4 years when diabetic ketoacidosis developed together with the emergence of ocular myasthenia findings.
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Conclusion & Impact:Although an autoimmune process may have triggered both autoimmune diseases at the same time in this case, we believe the diabetic ketoacidosis was a triggering factor for the JMG and discuss this association.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Juvenile myasthenia gravis (JMG) is an autoimmune disease caused by antibodies affecting the postsynaptic membrane at the neuromuscular junction. The association of JMG with Type I diabetes mellitus (DM), another autoimmune disease, is very rare and the pathogenesis has not been fully explained. Our case is the youngest patient where this association has been reported in the literature and presented at the age of 4 years when diabetic ketoacidosis developed together with the emergence of ocular myasthenia findings. She is the only case diagnosed with JMG among the 510 Type I DM patients followed-up at our clinic. Although an autoimmune process may have triggered both autoimmune diseases at the same time in this case, we believe the diabetic ketoacidosis was a triggering factor for the JMG and discuss this association.

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Cite This Article

KÜÇÜKALİ, G. K., BAŞER, Ş., ÖZKAN, M., ERDEVE, Ş., AYCAN, Z. (2019). A Myasthenia Gravis Case Diagnosed Simultaneously with Diabetic Ketoacidosis. The Journal of Pediatric Research, Cilt: 6 - Sayı: 1, 73–76. https://ajindex.com/articles/362899

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