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Journals / The Journal of Pediatric Research / 2020 / Cilt: 7 - Sayı: 1

Thyroid Function in Obese Children and Adolescents and its Relationships with Metabolic Parameters

Özlem KORKMAZ
Pages
7–12
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

A greater understanding of the association between thyroid function and obesity will be useful tothe development of strategies aimed at preventing or treating childhood obesity.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The purpose of this study was to evaluate levels of free thyroxin (T4) and thyroid-stimulating hormone (TSH) in obese children andadolescents, and to identify potential correlations between glucose and lipid metabolism parameters.Materials and Methods: One hundred obese patients aged 8-18 years were retrospectively evaluated in the pediatric endocrinology outpatientclinic.
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Key Findings & Data:All participants’ anthropometric measurements, free T4 and TSH concentrations, glucose levels and lipid profiles were recorded.Results: The mean age of the participants was 11.43±2.64 years.
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Conclusion & Impact:A greater understanding of the association between thyroid function and obesity will be useful tothe development of strategies aimed at preventing or treating childhood obesity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Aim: The purpose of this study was to evaluate levels of free thyroxin (T4) and thyroid-stimulating hormone (TSH) in obese children andadolescents, and to identify potential correlations between glucose and lipid metabolism parameters.Materials and Methods: One hundred obese patients aged 8-18 years were retrospectively evaluated in the pediatric endocrinology outpatientclinic. All participants’ anthropometric measurements, free T4 and TSH concentrations, glucose levels and lipid profiles were recorded.Results: The mean age of the participants was 11.43±2.64 years. TSH levels exhibited significant positive correlation with fasting blood glucoseand cholesterol levels. Multiple regression analysis showed that a one-unit increase in blood glucose and cholesterol raised TSH levels by0.047 units and 0.012 units, respectively.Conclusion: The relationship between thyroid function and other metabolic risk factors in obese children is still unclear. Our findings areimportant in terms of showing that obesity may exert a central effect on thyroid function, before the emergence of any effects on insulinlevels and anthropometric characteristics. A greater understanding of the association between thyroid function and obesity will be useful tothe development of strategies aimed at preventing or treating childhood obesity.

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Cite This Article

KORKMAZ, Ö. (2020). Thyroid Function in Obese Children and Adolescents and its Relationships with Metabolic Parameters. The Journal of Pediatric Research, Cilt: 7 - Sayı: 1, 7–12. https://ajindex.com/articles/362889

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