SavedAdd your journal

Journals / The Journal of Pediatric Research / 2020 / Cilt: 7 - Sayı: 1

Vitamin B12 Serum Levels of Six to Nine-monthold Infants According to Feeding Practices

Hüseyin DAĞ
Melike ÖZBERK KOÇ
Okan DİKKER
Hasan DURSUN
Pages
1–6
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, both mothers andbabies should be provided with the necessary support in terms of vitamin B12 levels, and prophylaxis should be discussed from the viewpointof preventive healthcare services.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Vitamin B12 is naturally obtained from animal-derived foods and is important for the development and wellbeing of babies.
📊
Key Findings & Data:Vitamin B12deficiency is a general health concern in developing countries.
💡
Conclusion & Impact:Therefore, both mothers andbabies should be provided with the necessary support in terms of vitamin B12 levels, and prophylaxis should be discussed from the viewpointof preventive healthcare services.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Aim: Vitamin B12 is naturally obtained from animal-derived foods and is important for the development and wellbeing of babies. Vitamin B12deficiency is a general health concern in developing countries. This study aimed to investigate the effects of different feeding practices onvitamin B12 levels and hemogram parameters in infants aged 6-9 months.Materials and Methods: A total of 120 infants (61 boys, 59 girls) aged 6-9 months were retrospectively evaluated. These babies were assigned tothree groups according to feeding practices: 1) only breast milk, 2) breast milk and formula, and 3) only formula in addition to complementaryfoods. Laboratory data (vitamin B12, hemoglobin, hematocrit, mean corpuscular volume, white blood cell count, and absolute neutrophilcount) of the patients were retrospectively compared.Results: The mean and median age of the patients was 6.6±1.1 months. The vitamin B12 levels in babies that only received formula werestatistically significantly higher than those in babies taking only breast milk or taking both breast milk and formula (p<0.05). Furthermore,vitamin B12 levels were significantly lower in babies receiving only breast milk than in those receiving both formula and breast milk (p<0.001).Conclusion: This study showed that vitamin B12 levels were lower in babies that only received breast milk compared to those in babiesreceiving formula. The babies that were receiving formula only had the highest levels of vitamin B12. This study determined that breast milkalone was not sufficient to maintain normal levels of vitamin B12 in 6 to 9-month-old babies in the region. Therefore, both mothers andbabies should be provided with the necessary support in terms of vitamin B12 levels, and prophylaxis should be discussed from the viewpointof preventive healthcare services.

🔖

Cite This Article

DAĞ, H., KOÇ, M. Ö., DİKKER, O., DURSUN, H. (2020). Vitamin B12 Serum Levels of Six to Nine-monthold Infants According to Feeding Practices. The Journal of Pediatric Research, Cilt: 7 - Sayı: 1, 1–6. https://ajindex.com/articles/362888

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Monsen AL, Refsum H, Markestad T, Ueland PM. Cobalamin status and its biochemical markers methylmalonic acid and homocysteine in different age groups from 4 days to 19 years. Clin Chem 2003;49:2067-75
  2. Allen LH. How common is vitamin B-12 deficiency? Am J Clin Nutr 2009;89:693S-6S
  3. Pawlak R, Parrott SJ, Raj S, Cullum-Dugan D, Lucus D. How prevalent is vitamin B(12) deficiency among vegetarians? Nutr Rev 2013;71:110-7
  4. Dror DK, Allen LH. Effect of vitamin B12 deficiency on neurodevelopment in infants: current knowledge and possible mechanisms. Nutr Rev 2008;66:250-5
  5. Ng’eno BN, Perrine CG, Whitehead RD, et al. High Prevalence of Vitamin B12 Deficiency and No Folate Deficiency in Young Children in Nepal. Nutrients 2017;9. pii: E72
  6. Jones KM, Ramirez-Zea M, Zuleta C, Allen LH. Prevalent vitamin B-12 deficiency in twelve-month-old Guatemalan infants is predicted by maternal B-12 deficiency and infant diet. J Nutr 2007;137:1307-13
  7. Gernand AD, Schulze KJ, Stewart CP, West KP Jr, Christian P. Micronutrient deficiencies in pregnancy worldwide: health effects and prevention. Nat Rev Endocrinol 2016;12:274-89
  8. Chebaya P, Karakochuk CD, March KM, et al. Correlations between Maternal, Breast Milk, and Infant Vitamin B12 Concentrations among Mother-Infant Dyads in Vancouver, Canada and Prey Veng, Cambodia: An Exploratory Analysis. Nutrients 2017;9. pii: E270
  9. Karademir F, Suleymanoglu S, Ersen A, et al. Vitamin B12, folate, homocysteine and urinary methylmalonic acid levels in infants. J Int Med Res. 2007;35:384-8
  10. Specker BL, Brazerol W, Ho ML, Norman EJ. Urinary methylmalonic acid excretion in infants fed formula or human milk. Am J Clin Nutr 1990;51:209-11
  11. Roschitz B, Plecko B, Huemer M, Biebl A, Foerster H, Sperl W. Nutritional infantile vitamin B12 deficiency: pathobiochemical considerations in seven patients. Arch Dis Child Fetal Neonatal Ed 2005;90:F281-2
  12. Brocadello F, Levedianos G, Piccione F, Manara R, Pesenti FF. Irreversible subacute sclerotic combined degeneration of the spinal cord in a vegan subject. Nutrition 2007;23:622-4
  13. Ludwig ML, Matthews RG. Structure-based perspectives on B12- dependent enzymes. Annu Rev Biochem 1997;66:269-313
  14. Kamei M, Ito Y, Ando N, et al. Brain atrophy caused by vitamin B12-deficient anemia in an infant. J Pediatr Hematol Oncol 2011;33:556-8
  15. Van Winckel M, Vande Velde S, De Bruyne R, Van Biervliet S. Clinical practice: vegetarian infant and child nutrition. Eur J Pediatr 2