Journals / The Journal of Pediatric Research / 2016 / Cilt: 3 - Sayı: 3

Çocuklarda Apendektomide Gelişen Nöroendokrin Yanıtın Açık ve Laparoskopik Yöntemlerde Karşılaştırılması: Randomize Kontrollü Çalışma

Comparison of Neuroendocrine Responses in Open and Laparoscopic Appendectomies in Children: A Randomized Controlled Trial

Pages
144–148
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

No significant difference was found between the responses developed in either group.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: To compare the neuroendocrine changes and responses to surgical stress in open and laparoscopic appendectomy techniques in children.Materials and Methods: Sixty-seven patients aged between six and 14 years presented to the pediatric surgery clinic between July and September 2008 with acute abdominal pain and were enrolled into this study.
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Key Findings & Data:Results: No statistical difference was observed between the open and laparoscopic appendectomy groups in terms of age, gender, weight, or duration of surgery (p>0.05).
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Conclusion & Impact:No significant difference was found between the responses developed in either group.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: To compare the neuroendocrine changes and responses to surgical stress in open and laparoscopic appendectomy techniques in children.Materials and Methods: Sixty-seven patients aged between six and 14 years presented to the pediatric surgery clinic between July and September 2008 with acute abdominal pain and were enrolled into this study. Patients had class I-II disease, according to the American Society of Anesthesiology, and were scheduled for open and laparoscopic appendectomies. The patients were randomly divided into two groups according to the method of appendectomy used. The neuroendocrine responses of both groups were then compared. Results: No statistical difference was observed between the open and laparoscopic appendectomy groups in terms of age, gender, weight, or duration of surgery (p>0.05). In addition, no statistical difference was observed between the mean arterial pressure (MAP), cardiac apex beat (CAB), peripheral oxygen saturation (SpO2), and end tidal carbon dioxide pressure (ETCO2) values of the open and laparoscopic appendectomy groups at 0, 5, 10, 15, 30, 60 minutes, and at the end of the operation (p>0.05). There was no statistical difference between the mean values of MAP, CAB, SpO2, or ETCO2 of the groups at the end of the operation and at 1, 2, 3, 12, and 24 hours postoperatively (p>0.05) or between the mean glucose, prolactin, or cortisol levels of the two groups at 0 and 30 minutes and at the end of the operation (p>0.05).Conclusions: This study demonstrated that neuroendocrine responses to surgical stress were similar in open and laparoscopic appendectomy operations in children. No significant difference was found between the responses developed in either group.

Özet

Amaç: Bu çalışmamızda çocuklarda açık ve laparoskopik apendektomi tekniklerinin cerrahi strese yanıtın ve oluşan nöro-endokrin değişikliklerin karşılaştırılması amaçlandı.Gereç ve Yöntemler: Temmuz ve Eylül 2008 tarihleri arasında çocuk cerrahisi kliniğine başvuran akut karın ağrısı olgularında açık ve kapalı laparoskopik apendektomi planlanan Amerikan Anesteziyoloji Derneği I-II, altı-14 yaş arası 67 olgu rastgele 2 grup oluşturularak her iki grubun nöro-endokrin yanıtı karşılaştırılmıştır. Bulgular: Açık apendektomi ve laparoskopik apendektomi gruplarının yaş ortalamaları, cinsiyet dağılımları, kilo ortalamaları, operasyon süresi ortalamaları arasında istatistiksel farklılık gözlenmemiştir (p>0,05). Açık apendektomi ve laparoskopik apendektomi gruplarının 0., 5., 10., 15., 30., 60. dakika ve operasyon sonu ortalama arter basıncı (OAB), kalp tepe atımı (KTA), periferik oksijen satürasyonu (SPO2), endtidal karbon dioksit basıncı (ETCO2) ortalamaları arasında istatistiksel farklılık gözlenmemiştir (p>0,05). Ayrıca her iki grubun Post Op., 1., 2., 4., 12., 24. saat OAB, KTA, SPO2, ETCO2 ortalamaları arasında istatistiksel farklılık gözlenmemiştir (p>0,05). Açık apendektomi ve laparoskopik apendektomi gruplarının 0. ve 30. dakika operasyon sonu glikoz, prolaktin, kortizol ortalamaları arasında istatistiksel farklılık gözlenmemiştir (p>0,05).Sonuç: Çalışmamızda çocuklarda açık ve laparoskopik apendektomilerde cerrahi strese karşı gelişen nöro-endokrin yanıtın benzer olduğu gösterilmiştir. Her iki grupta gelişen nöro-endokrin yanıt arasında bir fark tespit edilmemiştir.

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Cite This Article

SALKAYA, A. E., ÖZBAĞRIAÇIK, Ö., AKAY, A., OBA, S., ARSLAN, S. (2016). Çocuklarda Apendektomide Gelişen Nöroendokrin Yanıtın Açık ve Laparoskopik Yöntemlerde Karşılaştırılması: Randomize Kontrollü Çalışma. The Journal of Pediatric Research, Cilt: 3 - Sayı: 3, 144–148. https://ajindex.com/articles/362846

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