SavedAdd your journal

Journals / The Journal of Pediatric Research / 2018 / Cilt: 5 - Sayı: 4

Neutropenic Fever in a Two-and-a-Half Month Old Girl: Severe Congenital Neutropenia

Hüseyin GÜLEN
Merve ÖÇALAN
Ayşen TÜREDİ YILDIRIM
F. Sırrı ÇAM
Hamide Betül GERİK ÇELEBİ
Pages
225–227
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we present a case of a two and a half month old girl who was admitted to our clinic with fever and absolute neutropenia was determined in her clinical course.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Severe congenital neutropenia is a hereditary disease characterized by a low number of neutrophils occurring from the first months of life leading to severe infections.
📊
Key Findings & Data:It is rare but threatens life because of severe infections.
💡
Conclusion & Impact:Here, we present a case of a two and a half month old girl who was admitted to our clinic with fever and absolute neutropenia was determined in her clinical course.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Severe congenital neutropenia is a hereditary disease characterized by a low number of neutrophils occurring from the first months of life leading to severe infections. It is rare but threatens life because of severe infections. For this reason, early diagnosis and treatment of this disease is important. Here, we present a case of a two and a half month old girl who was admitted to our clinic with fever and absolute neutropenia was determined in her clinical course.

🔖

Cite This Article

GÜLEN, H., ÖÇALAN, M., YILDIRIM, A. T., ÇAM, F. S., ÇELEBİ, H. B. G. (2018). Neutropenic Fever in a Two-and-a-Half Month Old Girl: Severe Congenital Neutropenia. The Journal of Pediatric Research, Cilt: 5 - Sayı: 4, 225–227. https://ajindex.com/articles/362811

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Barış S, Karakoç Aydıner E, Kıykım A, et al. The phenotypegenotype relationship in severe congenital neutropenia patients. Turk Pediatri Ars 2012;47:272-7.
  2. Celkan T, Koç BŞ. Approach to the patient with neutropenia in childhood. Turk Pediatri Ars 2015;50:136-44.
  3. Welte K, Zeidler C, Dale DC. Severe congenital neutropenia. Semin Hematol 2006;43:189-95.
  4. Edeer Karaca N, Aksu G, Gulez N, et al. Clinical, Laboratory and Molecular Approach to Ten Children with Congenital Neutropenia. J Pediat Res 2016;3:7-12.
  5. Boztug K, Klein C. Genetic etiologies of severe congenital neutropenia. Curr Opin Pediatr 2011;23:21-6.
  6. Dale DC, Person RE, Bolyard AA, et al. Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia. Blood 2000;96:2317-22.
  7. Horwitz MS, Duan Z, Korkmaz B, Lee HH, Mealiffe ME, Salipante SJ. Neutrophil elastase in cyclic and severe congenital neutropenia. Blood 2007;109:1817-24.
  8. Smith BN, Ancliff PJ, Pizzey A, Khwaja A, Linch DC, Gale RE. Homozygous HAX1 mutations in severe congenital neutropenia patients with sporadic disease: A novel mutation in two unrelated British kindreds. Br J Haematol 2009;144:762-70.
  9. Rosenberg PS, Zeidler C, Bolyard AA, et al. Stable long-term risk of leukemia in patients with severe congenital neutropenia maintained on G-CSF therapy. Br J Haematol 2010;150:196-9.