Journals / The Journal of Breast Health / 2017 / Cilt: 13 - Sayı: 1

Radiation Fibrosis Syndrome Imitating Breast Cancer Recurrence; A Case Report

Pages
40–42
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Her physical examination and radiologic findings revealed a big mass invading right thoracic wall, thoracic cavity and the axilla.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Nowadays, surgery, radiotherapy and chemotherapy are the most frequently used modalities in the treatment of breast cancer.
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Key Findings & Data:It is very well-known that some severe complications may result from after these treatments.
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Conclusion & Impact:Her physical examination and radiologic findings revealed a big mass invading right thoracic wall, thoracic cavity and the axilla.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Nowadays, surgery, radiotherapy and chemotherapy are the most frequently used modalities in the treatment of breast cancer. It is very well-known that some severe complications may result from after these treatments. Early and late complications of radiotherapy are well known. fte complica- tions of radiation therapy may be seen in (early) or after three months (late-delayed) of periods. ftese complications may be related with direct or indirect effect of radiation. fte radiation fibrosis syndrome is a progressive fibrotic tissue sclerosis together with various clinical symptoms in the irradiation field. It is usually a late finding of radiation therapy and may be seen weeks or even years after the treatment. Many systems such as musculo-skeletal, soft tissue, neural tissue and cardiopulmonary system may be affected. In this report, we present a case of a breast cancer treated with breast conserving surgery and radiation therapy twelve years ago. fte patient had ipsilateral lymphedema, right axillary mass, and pain during arm and shoulder mobilization. Her physical examination and radiologic findings revealed a big mass invading right thoracic wall, thoracic cavity and the axilla. Histopathological evaluation performed after tru-cut and open biopsy from the mass showed fibrosis resulting from radiation therapy.

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Cite This Article

SARSANOV, D., AKTEPE, F., ÖZMEN, V. (2017). Radiation Fibrosis Syndrome Imitating Breast Cancer Recurrence; A Case Report. The Journal of Breast Health, Cilt: 13 - Sayı: 1, 40–42. https://ajindex.com/articles/362634

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References (9)

  1. Pohlers D, Brenmoehl J, Loffler I. TGF-β and fibrosis in different organs – molecular pathway imprints. Biochim Biophys Acta 2009
  2. (PMID: 19539753) Delanian S, Lefaix JL. Current management of late normal tissue inju- ry: radiation-induced fibrosis and necrosis. Semin Radiat Oncol 2007
  3. (PMID: 17395040) [CrossRef] Stubblefield MD. Cancer rehabilitation. Semin Oncol 2011
  4. (PMID: 21600368) [CrossRef] Stubblefield MD, Burstein HJ, Burton AW, Custodio CM, Deng GE, Ho M, Junck L, Morris GS, Paice JA, Tummala S, Von Roenn JH. NCCN task force report: management of neuropathy in cancer. J Natl Compr Canc Netw 2009
  5. S1-26. (PMID: 19755042) Hojan K, Milecki P. Opportunities for rehabilitation of patients with ra- diation fibrosis syndrome. Reports of practical oncology and radiotherapy 2014
  6. (PMID: 24936313) Hammer C, Maduro JH, Bantema-Joppe EJ, van der Schaaf A, van der Laan HP, Langendijk JA, Crijns AP. Radiation-induced fibrosis in the boost area after three-dimensional conformal radiotherapy with a simultaneous integrated boost technique for early-stage breast cancer: A multivariable prediction model. Radiother Oncol 2016
  7. pii:S0167-8140(16)34342-0. (PMID: 27793444) Delanian S, Porcher R, Rudant J, Lefaix JL. Kinetics of response to long- term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis. J Clin Oncol 2005
  8. (PMID: 16260695) [CrossRef] Teguh DN, Bol Raap R, Struikmans H, Verhoef C, Koppert LB, Koole A, Huang Y, van Hulst RA. Hyperbaric oxygen therapy for late radia- tion-induced tissue toxicity: prospectively patient-reported outcome measures in breast cancer patients. Radiat Oncol 2016
  9. (PMID: 27682427)[CrossRef]