Journals / The European Research Journal / 2020 / Cilt: 6 - Sayı: 6

Evaluation of the effects on atherosclerosis and antioxidant and antimicrobial activities of Agaricus xanthodermus poisonous mushroom

Pages
539–544
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: In conclusion, A. xanthodermus is considered to be a poisonous mushroom and can be used as a pharmacological natural agent due to its high antioxidant and antimicrobial activities.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: The aim of this study was to determine the total antioxidant capacity, total oxidant capacity, oxidative stress index and antimicrobial activity of a poisonous mushroom Agaricus xanthodermus.
📊
Key Findings & Data:Antimicrobial activities were tested on 9 microorganisms (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Candida albicans, C.krusei and C. glabrata) using the modified agar dilution method.
💡
Conclusion & Impact:Conclusions: In conclusion, A. xanthodermus is considered to be a poisonous mushroom and can be used as a pharmacological natural agent due to its high antioxidant and antimicrobial activities.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Medicinal mushroom · poisonous mushrooms · Agaricus xanthodermus

Abstract

Objectives: The aim of this study was to determine the total antioxidant capacity, total oxidant capacity, oxidative stress index and antimicrobial activity of a poisonous mushroom Agaricus xanthodermus. The effects of mushrooms on atherosclerosis are due to their antioxidant effects. Methods: Mushroom samples collected from study field were extracted with methanol (MeOH) and dichloromethane (DCM) using soxhlet apparatus. Total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) were measured using Rel Assay trade kits. Antimicrobial activities were tested on 9 microorganisms (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Candida albicans, C.krusei and C. glabrata) using the modified agar dilution method. Results: In this study A. xanthodermus has shown high antioxidant and antimicrobial activities. In addition, the highest activities of MeOH and DCM extracts of the mushrooms were demonstrated against E. coli, P. aeruginosa, and A. baumannii. Conclusions: In conclusion, A. xanthodermus is considered to be a poisonous mushroom and can be used as a pharmacological natural agent due to its high antioxidant and antimicrobial activities.

🔖

Cite This Article

ÖZALTUN, B., SEVİNDİK, M. (2020). Evaluation of the effects on atherosclerosis and antioxidant and antimicrobial activities of Agaricus xanthodermus poisonous mushroom. The European Research Journal, Cilt: 6 - Sayı: 6, 539–544. https://ajindex.com/articles/361030

References (14)

  1. Lima AD, Costa Fortes R, Garbi Novaes MRC, Percário S. Poisonous mushrooms; a review of the most common intoxications. Nutr Hosp 2012;27:402-8
  2. Jo WS, Hossain MA, Park SC. Toxicological profiles of poisonous, edible, and medicinal mushrooms. Mycobiology 2014;42:215-20
  3. White J, Warrel D, Eddleston M, Currie BJ, White IM, Isbister GK. Clinical toxinology --Where are we now? J Toxicol Clin Toxicol 2003;41:263-76
  4. Flesch F, Saviuc P. [Mushroom poisoning: syndromes and treatment] EMC-Médecine 2004;1:70-9. [Article in French] 5. Ecevit Ç, Hızarcıoğlu M, Gerçek PA, Gerçek H, Kayserili E, Gülez P, et al. [Evaluation of musroom intoxications presenting at the emercency department of Dr. Behçet Uz children's hospital]. ADÜ Tıp Fak Derg 2004;5(3):11-14. [Article in Turkish] 6. Catcheside P, Yellow Stainer, State Herbarium Factsheet, Government of South Australia, 2017
  5. Hender E, May T, Beulke S. Poisoning due to eating fungi in Victoria. Aust Fam Physician 2000;29:1000-4
  6. Beug W, Shaw M, Cochran KW. Thirty plus years of mushroom poisoning: summary of the approximately 2,000 reports in the NAMA case registry. McIlvainea 2006;16:47-68
  7. Valverde ME, Hernández-Pérez T, Paredes-López O. Edible mushrooms: improving human health and promoting quality life. Int J Microbiol 2015; 2015:376387
  8. Calvo AM, Wilson RA, Bok JW, Keller NP. Relationship between secondary metabolism and fungal development. Microbiol Mol Biol Rev 2002;66:447-59
  9. Wieczorek Z, Siemion IZ, Bolewska-Pedyczak E, Wieland T. Immunosuppressive activity in the series of cycloamanide peptides from mushrooms. Peptides 1993;14:1-5
  10. Badalyan SM, Innocenti G, Garibyan NG. Antagonistic activity of xylotrophic mushrooms against pathogenic fungi of cereals in dual culture. Phytopathol Mediterr 2002;41;220-5
  11. Lull C, Wichers HJ, Savelkoul HF. Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm 2005;2:63-80
  12. Ede SO, Olaniru E, Otimenyin S, Aguiyi JC, Ekwere EO. Analgesic and anti inflammatory activities of the ethanolic extract of the mushroom Ganoderma applanatum. IJRRAS 2012;13:349-52
  13. Moharib SA, El Maksoud NA, Ragab HM. Anticancer activities of mushroom polysaccharides on chemically-induced colorectal cancer in rats. J Appl Pharma Sci 2014;4:54-63
  14. Merdivan S, Lindequist U. Medicinal mushrooms with antiallergic activities. In: Agrawal DC, Tsay HS, Shyur LF, Wu YC, Wang SY, eds. Medicinal Plants and Fungi: Recent Advances in Researc