Journals / Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi / 2020 / Cilt: 11 - Sayı: 2

Ameloblastic Fibro-Odontoma Misinterpreted Histopathologically After Insufficient Biopsy: A Case Report

Yetersiz Biyopsi Sonrası Yanlış Yorumlanan Ameloblastik Fibro-Odontoma Vakası: Olgu Sunumu

Pages
282–286
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, as in our case, biopsy sections should be performed completely to prevent histopathological misinterpretations.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Ameloblastic fibro-odontoma (AFO) is a rare benign odontogenic tumor caused by proliferation of epithelial and mesenchymal cells.
📊
Key Findings & Data:Case: A 9-year-old male patient who applied to our clinic with a complaint of swelling that did not pass in the right mandibular posterior region was decided to take a biopsy first, and then the diagnosis of the mass was made as Ameloblastic Fibroma (AF).
💡
Conclusion & Impact:However, as in our case, biopsy sections should be performed completely to prevent histopathological misinterpretations.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Ameoblastik fibroma · ameoblastik fibro-odontoma · histopatolojik inceleme

Abstract

Objective: Ameloblastic fibro-odontoma (AFO) is a rare benign odontogenic tumor caused by proliferation of epithelial and mesenchymal cells. It is generally seen in children and has an asymptomatic course. In terms of classification, AFO has similar features to other lesions in the same group. In our case, the case of AFO which was misdiagnosed as a result of incomplete biopsy is presented and in the histopathological differential diagnosis of the lesion, the importance of taking biopsy samples completely is emphasized. Case: A 9-year-old male patient who applied to our clinic with a complaint of swelling that did not pass in the right mandibular posterior region was decided to take a biopsy first, and then the diagnosis of the mass was made as Ameloblastic Fibroma (AF). However, in the second histopathological examination performed as a result of surgical excision of the lesion, the mass was reported to be AFO. In the patient's postoperative controls, healing was observed to be smooth and no recurrence was encountered. Conclusion: There are also discussions in the literature about whether AFO is a different stage of odontoma or a different pathology. Histopathological examination should be done carefully for a definitive diagnosis. However, as in our case, biopsy sections should be performed completely to prevent histopathological misinterpretations.

Özet

Amaç: Ameloblastik fibro-odontoma (AFO) epitelyal ve mezenşimal hücrelerin proliferasyonu sonucu oluşan, nadir görülen, iyi huylu odontojenik bir tümördür. Genellikle çocuklarda görülür ve asemptomatik seyirlidir. AFO sınıflandırma bakımından aynı grupta bulunan diğer lezyonlara benzer özellikler taşımaktadır. Sunduğumuz olguda da eksik biyopsi sonucu yanlış teşhis konulan AFO vakası sunulmakta ve lezyonun histopatolojik olarak ayırıcı teşhisinde biyopsi örneklerinin eksiksiz alınmasının önemi vurgulanmaktadır. Olgu: Sağ mandibular posterior bölgesinde geçmeyen şişlik şikayetiyle kliniğimize başvuran 9 yaşındaki erkek hastada öncelikle biyopsi yapılmasına karar verildi ve ardından kitlenin teşhisi Ameloblastik Fibroma (AF) olarak konuldu. Ancak lezyonun cerrahi eksizyonu sonucu yapılan ikinci histopatolojik incelemede kitlenin AFO olduğu rapore edildi. Hastanın postoperatif dönemde yapılan kontrollerinde ise iyileşmenin sorunsuz olduğu görüldü ve herhangi bir nüksle karşılaşılmadı. Sonuç: AFO’nın literatürde odontomanın farklı bir safhası mı yoksa farklı bir patoloji mi olduğu konusunda da tartışmalar bulunmaktadır. Kesin teşhis için histopatolojik incelemenin dikkatle yapılması gerekmektedir. Ancak biyopsi kesitlerinin eksiksiz olması vakamızda karşılaştığımız gibi histopatolojik açıdan yanlış yorumlamaların önene geçecektir.

🔖

Cite This Article

KURT, M. Y., EGE, B., ÖRMECİ, A. G. (2020). Ameloblastic Fibro-Odontoma Misinterpreted Histopathologically After Insufficient Biopsy: A Case Report. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi, Cilt: 11 - Sayı: 2, 282–286. https://ajindex.com/articles/360466

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (5)

  1. Cohen DM, Bhattacharyya I. Ameloblastic fibroma, ameloblastic fibro‑odontoma, and odontoma. Oral Maxillofac Surg Clin North Am. 2004;16:375‑384. Barnes L, Eveson JW, Reichart P, et al. (eds) World Health Organization classification of tumours: pathology and genetics of head and neck tumours. Lyon: IARC Press, 2005.
  2. Pontes HAR, Pontes FSC, Lamerira AG, Salim RA, Carvalho PL, Guimarães DM, et al. Report of four cases of ameloblastic fibro-odontoma in mandible and discussion of the literature about the treatment. J Craniomaxillofac Surg. 2012;40:e59-e63. Martinez Martinez M, Romero CS, Pina AR, Palma Guzmán JM, de Almeida OP. Pigmented amelobalstic fibro-odontoma: clinical, histological, and immunohistochemical profile. Int J Surg Pathol. 2015;23:52-60.
  3. Phillips MD, Closmann JJ, Baus MR, Torske KR, Williams SB. Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature. J Oral Maxillofac Surg. 2010;68:470-474.
  4. Philipsen HP, Reichart PA, Praetorius F. Mixed odontogenic tumours and odontomas. Considerations on interrelationship. Review of the literature and presentation of 134 new cases of odontomas. Oral Oncol. 1997;33:86-99. Tomich CE. Benign mixed odontogenic tumors. Semin Diagn Pathol. 1999; 16: 308-316. Slootweg PJ. An analysis of the interrelationship of mixed odontogenic tumors-ameloblastic fibroma, ameloblastic fibro-odontoma, and the odontomas. Oral Surg Oral Med Oral Pathol. 1981;51:266-276.
  5. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and Maxillofacial Pathology. New York: NY: Elsevier; 2009. Mosqueda-Taylor A. New findings and controversies in odontogenic tumors. Med Oral Patol Cir Buccal. 2008;13:e55. Chrcanovic BR, Gomez RS. Ameloblastic fibrodentinoma and ameloblastic fibro‑odontoma: An updated systematic review of cases reported in the literature. J Oral Maxillofac Surg. 2017;75:1425‑1437. Lee J, Song YG, Moon SY, Choi B, Kim BC, Yoon JH. Calcifying cystic odontogenic tumor associated with ameloblastic fibro-odontoma of the anterior mandible. J Craniofac Surg. 2014;25:e259-260. Oghli AA, Scuto I, Ziegler C, Flechtenmacher C, Hofele C. Ameloblastic fibro-odontoma: A large ameloblastic fibro-odontoma of the right mandible. Med Oral Patol Oral Cir Bucal. 2007;12:E34-37. Gardner DG. The mixed odontogenic tumors. Oral Surg Oral Med Oral Pathol. 1984;58:166‑168. Zouhary KJ, Said-Al-Naief N, Waite PD. Ameloblastic fibro-odontoma: ex