Journals / Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi / 2019 / Cilt: 10 - Sayı: 4

The Relationship Between Echocardiographic Epicardial Fat Tissue Thickness and Clinical & Haematological Parameter

Ekokardiyografik Epikardiyal Yağ Dokusu Kalınlığı ile Klinik & Hematolojik Parametreler Arasındaki İlişki

Pages
417–422
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The study result has strengthened the role in determining the risk and prognosis of these two markers.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Recently numerous markers for risk assessment are being investigated for many diseases especially in ischemic heart diseases.
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Key Findings & Data:Material-Method: A total of 223 consecutive subjects (136 males and 87 females) were enrolled to the study.
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Conclusion & Impact:The study result has strengthened the role in determining the risk and prognosis of these two markers.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Recently numerous markers for risk assessment are being investigated for many diseases especially in ischemic heart diseases. Epicardial adipose tissue (EAT) and hematological parameters (platelet count, mean platelet volume (MPV) , reticulocyte distribution width (RDW), neutrophil lymphocyte ratio (NLR) , platelet- lymphocyte ratio (PLR) ) are some of these markers. In our study the relations between EAT measured by echocardiography and hematologic parameters were evaluated. Material-Method: A total of 223 consecutive subjects (136 males and 87 females) were enrolled to the study. The subjects who were diagnosed with ischemic heart disease were excluded from the study. Hematological parameters and EAT thickness which was measured with standard echocardiographic technique of all the subjects who were included in the study were measured at the time of admission to the hospital. The participants were divided into two groups according to their EAT thickness; 107 subjects with <0,7 cm were identified as group1, 116 subjects ≥0,7 cm were identified as group 2. The relationship between EAT and hematological parameters were evaluated. Results: The group 2 was older (mean age 57.02±10.91 vs. 62.79±9.85; p=0.001) and more obese (body mass index 28.40±4.18 vs. 30, 68±5.59; p=0.001) than group 1. Group 2 had greater prevalence of hypertension and diabetes mellitus. Only NLR values from hematological parameters were found significantly higher in group 2 compared to group 1 (1,88±0,72 vs. 2,15±0,85; p=0,028). A correlation close to statistical significance between EAT thickness and NLR was determined (R:0,143 p=0,055). Conclusions: NLR was the only hematological parameter which a relation was determined with EAT thickness. The study result has strengthened the role in determining the risk and prognosis of these two markers.

Özet

Amaç: Son zamanlarda özellikle iskemik kalp hastalıklarıolmak üzere pekçok hastalıkta risk ve prognoz tayinindeyeni belirteçler araştırma konusu olmaktadır. Epikardiyalyağ dokusu ve hematolojik parametreler (trombosit sayısı,ortalama trombosit hacmi(MPV), retikulosit dağılım genişliği(RDW), nötrofil lenfosit oranı (NLR), trombosit lenfosit oranı(PLR)) bu belirteçlerdendir. Çalışmamızda ekokardiyografiile ölçülen epikardiyal yağ dokusu kalınlığı ile hematolojikparametreler arasındaki ilişki araştırılmıştır.Materyal-Metot: Çalışmaya 136 erkek 87 kadın olmak üzere223 kişi dahil edildi. İskemik kalp hastalığı tanısı olanlarçalışmadan dışlandı. Çalışmaya dahil edilen tüm kişilerinbaşvuru anında hematolojik parametreleri ölçüldü ve standartteknik ile transtorasik ekokardiyografi yapılarak epikardiyalyağ dokusu kalınlıkları hesaplandı. Çalışmaya katılanlarepikardial yağ dokusu kalınlıklarına göre iki gruba ayrıldı,<0,7cm olan 107 hasta grup 1 ve ≥ 0,7 olan 116 hasta grup2 olarak belirlendi. Epikardiyal yağ kalınlığı ile hematolojikparametreler arasındaki ilişki istatiksel yöntemler iledeğerlendirildi.Bulgular: Epikardiyal yağ dokusu kalınlığı fazla olangrup daha yaşlı (ortalama yaş 57,02±10,91 vs. 62,79±9,85;p=0,001) ve daha kiloluydu(vücut kitle indeksi 28,40±4,18vs. 30,68±5,59; p=0,001). Grup 2’de diabetes mellitus vehipertansiyon sıklığı fazlaydı. Hematolojik parametrelerdenyalnızca NLR değeri grup 2’de grup 1’e göre anlamlıdüzeyde yüksek saptandı (1,88±0,72 vs. 2,15±0,85; p=0,028).Epikardiyal yağ dokusu kalınlığı ile NLR değeri arasındaistatiksel anlamlılığa yakın korelasyon saptandı(R:0,143p=0,055).Sonuç: Ekokardiyografik epikardiyal yağ dokusu kalınlığıile hematolojik parametrelerden yalnızca NLR arasında ilişkisaptanmıştır. Çalışma sonucu bu iki belirtecin daha öncekiçalışmalarda ortaya konmuş risk ve prognoz tayinindekirolünü desteklemektedir.

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Cite This Article

ATEŞ, İ. (2019). The Relationship Between Echocardiographic Epicardial Fat Tissue Thickness and Clinical & Haematological Parameter. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi, Cilt: 10 - Sayı: 4, 417–422. https://ajindex.com/articles/360324

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