AI Summary & Key Takeaways
AI InsightControlsof disease activation and prevention of progression in DM may provide to keep SQ in PS.
📌 3 Key Takeaways
Özet
Objectives: Psoriasis (PS) is a chronic, immune-mediated inflammatory skin disease. PS may lead to significant effects on healthrelatedquality of life (HRQoL) and other outcomes. In the present study, an investigation into sleep quality (SQ), and its possiblerelations with factors which may affect SQ were aimed.Methods: A total of 74 subjects from both sexes were enrolled in this study, between January and July 2017. Patients were evaluatedwith their demographics, body mass index (BMI), Psoriasis Area Severity Index (PASI), Pittsburgh Sleep Quality Index (PSQI),Psoriasis Quality of Life Index (PQLI), Self Perception Scale (SPS). Additionally, accompanying chronic diseases, disease duration andseverity of pruritus were recorded. Obtained PSQI values were compared with the mentioned parameters concerning the significanceof their relations with it. SPSS version 24, 2016 was used to analyse the data, and significance was evaluated with p-values of 0.8.Results: Thirty-seven female and 37 male were studied. The mean age of total of the study population was 47.21±13.91. Mean BMIand mean duration were 30.09± 4.68 kg/m2, and 10.58±9.1 months. Mean values of PASI, PSQI, SPS, and PQLI of the study groupwere 19.79±16.99, 9.14±5.09, 142.12±23.83, and 21.94±16.31, respectively. Approximately thirty-one percent of them had at leastone chronic disease. Alcohol and smoking rates were 17.56%, 50%. PASI was positive/strongly correlated with PQLI and negative/weakly correlated with SPS. No correlation was detected between PSQI values and age, gender, BMI, and SPS values. PSQI wasmoderately correlated with PQLI, diabetes mellitus (DM), and pruritus severity, whereas it was weak correlated with PASI, hypertension(HT), thyroid diseases and disease duration. PASI and DM showed a predictive effect on SQ.Conclusion: SQ is affected by certain factors, such as QoL, disease severity, disease duration, pruritus severity, accompanying disorders,such as HT, DM and thyroid diseases, in which disease severity and DM have predictive effects on SQ in PS patients. Controlsof disease activation and prevention of progression in DM may provide to keep SQ in PS.