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Journals / Türk Serebrovasküler Hastalıklar Dergisi / 2004 / Cilt: 10 - Sayı: 3

The effect of body temperature alteration on cerebral blood flow velocity in the rats developed experimental subaracnoid hemorrhage

Deneysel subaraknoid modeli geliştirilen ratlarda vücut ısısı değişikliklerinin serebral kan akım hızları üzerine etkisi

Serhat ÖZKAN
Demet ÖZBABALIK
Nevzat UZUNER
Gazi ÖZDEMİR
Pages
117–120
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hyperthermia also can be worst prognostic value.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate the effects of changing body temperature on mean cerebral blood flow velocity by using Transcranial doppler.
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Key Findings & Data:Material and methods: This study included in 30 rats separated 3 groups (normothermia, hypothermia and hyperthermia) after exposing to experimental subaracnoid hemorrhage model.
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Conclusion & Impact:Hyperthermia also can be worst prognostic value.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Kan akım hızı · Vücut sıcaklığı değişiklikleri · Hipotermi

Abstract

Purpose: To investigate the effects of changing body temperature on mean cerebral blood flow velocity by using Transcranial doppler. Material and methods: This study included in 30 rats separated 3 groups (normothermia, hypothermia and hyperthermia) after exposing to experimental subaracnoid hemorrhage model. The mean blood flow velocities of all groups were recorded by using Transcranial doppler first, 30th, 60., 120., 240., 360 minutes after procedure. Results: While the mean blood flow velocities of whole rats reduced in the 1st minutes after SAK, pulsatility index increased. In the hypothermia groups, mBFv did not show increasing during the experiment. In the contrast, normothermia and hyperthermia tended to higher than hypothermia, significantly. Conclusion: Hypothermia can prevent luxury perfusion in the early time of SAK. Hyperthermia also can be worst prognostic value.

Özet

Amaç: Subaraknoid kanama (SAK) sonrası vücut ısısı değişikliklerinin serebral kan akım hızları üzerine etkilerinin Transkranyal Doppler ile incelenmesi. Gereç ve Yöntem: Bu çalışma deneysel SAK geliştirildikten sonra 3 gruba (normotermi, hipertermi, hipotermi) ayrılarak izlenen 30 ratı içermektedir. Tüm grupların ortalama kan akım hızları TCD yardımıyla işlemden sonraki 1, 20, 60, 120, 240 ve 360. dakikalarda kayıtlanmıştır. Sonuçlar: SAK sonrası 1. dakikalarda tüm gruplarda ortalama kan akım hızları düşerken Pulsatilite indeksleri yüksek seyretti. Hipotermi grubunda deney süresince ortalama kan akım hızı düşük seyrederken normotermi ve hipertermi grubunda anlamlı şekilde yüksek seyretti. Tartışma; Hipotermi SAK erken döneminde lüks perfüzyondan koruyucu olarak davranırken, hipertermi kötü prognostik bir değer olabilir.

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Cite This Article

ÖZKAN, S., ÖZBABALIK, D., UZUNER, N., ÖZDEMİR, G. (2004). The effect of body temperature alteration on cerebral blood flow velocity in the rats developed experimental subaracnoid hemorrhage. Türk Serebrovasküler Hastalıklar Dergisi, Cilt: 10 - Sayı: 3, 117–120. https://ajindex.com/articles/357818

References (1)

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