Journals / Akademik Gastroenteroloji Dergisi / 2021 / Cilt: 20 - Sayı: 2

Etiology and diagnosis of cholestatic liver diseases in the geriatric population: A single-center experience of 185 cases

Geriatrik popülasyonda kolestatik karaciğer hastalıklarında etiyoloji ve tanısal yaklaşım: 185 vakalık tek merkez deneyimi

Pages
94–103
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In addition, both conditions were statistically significant (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background and aims: In this study, we aimed to analyze the etiology of cholestasis in a large geriatric patient population according to their complaints, laboratory parameters, and imaging results.
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Key Findings & Data:Materials and methods: A total of 185 geriatric patients (age: > 65 years) with cholestasis were included in this retrospective study.
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Conclusion & Impact:In addition, both conditions were statistically significant (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kolestaz · geriatrik popülasyon · sarılık

Abstract

Background and aims: In this study, we aimed to analyze the etiology of cholestasis in a large geriatric patient population according to their complaints, laboratory parameters, and imaging results. Materials and methods: A total of 185 geriatric patients (age: > 65 years) with cholestasis were included in this retrospective study. The patients were divided into two groups, i.e., benign etiology and malignant etiology, in order to further analyze parameters that could indicate malignancy. Results: A total of 109 (58.9%) patients had benign etiologies and 69 (37.3%) had malignant etiologies. The most common etiologies were choledocholithiasis [56 patients (30.3%)], cholangiocellular carcinoma [25 patients (13.5%)], and pancreatic cancer [23 patients (12.4%)]. The chief complaint was abdominal pain. In patients with jaundice, benign diseases accounted for approximately 45.6% of etiologies, whereas malignant diseases accounted for approximately 54.4% of etiologies. In patients with weight loss, benign diseases accounted for approximately 6.2% of etiologies, whereas malignant diseases accounted for approximately 93.8% of etiologies. In addition, both conditions were statistically significant (p

Özet

Giriş ve Amaç: Kolestaz etiyolojik nedenlerinin ve klinik bulgularının 65 yaş üstü hastalarda geniş hasta popülasyonu ile dökümante edilmesi amaçlandı. Gereç ve Yöntem: Kolestaz nedeniyle yatışı yapılan 65 yaş ve üstü hastalar retrospektif olarak şikayetleri, laboratuvar parametreleri ve görüntüleme sonuçlarına göre değerlendirildi. Benign ve malign etiyolojik nedenler olarak iki gruba ayrılan hastalarda malignite göstergesi olabilecek parametreler için ileri analiz yapıldı. Bulgular: Çalışmamıza retrospektif olarak 65 yaş ve üstü 185 hasta dahil edildi. 109 (%58.9) hastanın etiyolojisi benign, 69 (%37.3) hastanın malign nedenlere bağlı olarak saptandı. 56 hastada (%30.3) koledokolitiazis, 25 hastada (%13.5) kolanjioselüler karsinom, 23 hastada (%12.4) pankreas kanseri en sık görülen tanılardı. En sık başvuru şikayeti karın ağrısıydı. Sarılık şikayetiyle başvuran hastaların %45.6’sı (n: 52) benign, %54.4’ü (n: 62) malign iken kilo kaybıyla başvuran hastaların %6.2’si benign, %93.8’i maligndi. Sarılık ve/veya kilo kaybı şikayetiyle başvuran hastaların malign olma ihtimali istatistiksel olarak anlamlı düzeyde yüksek saptandı (p

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Cite This Article

KÖKER, G., UYAR, S., KÖKER, G. Ö., ÇATLI, M. M., ŞAHİNTÜRK, Y., BOSTAN, F., ÇEKİN, A. H. (2021). Etiology and diagnosis of cholestatic liver diseases in the geriatric population: A single-center experience of 185 cases. Akademik Gastroenteroloji Dergisi, Cilt: 20 - Sayı: 2, 94–103. https://ajindex.com/articles/356739

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