Journals / Anadolu Psikiyatri Dergisi / 2010 / Cilt: 11 - Sayı: 2

Detection of regional blood flow in borderline personality disorder

Sınır kişilik bozukluğunda bölgesel beyin kan akımı

Pages
102–111
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: As the dysfunction is compatible with the disorder's core symptoms, neuroimaging studies can contribute to the endo-phenotype studies which take into consider the clinical dimensions of BPD.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To assess the role of SPECT (Single Photon Emission Computed Tomography) in the diagnosis of BPD (borderline personality disorder).
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Key Findings & Data:Methods: Twenty BPD patients assessed with SCID-CV (Structured Clini-cal Interview for Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition Axis I Disorders, Clinical Version) and had no comorbid diagnoses have been assessed with SPECT, these images were compared to the cerebral blood flow of 17 healthy individuals.
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Conclusion & Impact:Conclusion: As the dysfunction is compatible with the disorder's core symptoms, neuroimaging studies can contribute to the endo-phenotype studies which take into consider the clinical dimensions of BPD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To assess the role of SPECT (Single Photon Emission Computed Tomography) in the diagnosis of BPD (borderline personality disorder). Methods: Twenty BPD patients assessed with SCID-CV (Structured Clini-cal Interview for Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition Axis I Disorders, Clinical Version) and had no comorbid diagnoses have been assessed with SPECT, these images were compared to the cerebral blood flow of 17 healthy individuals. The patients SPECT images were also assessed according to the clinical data that has been gathered via SCID-II (Personality Disorders assessment of Structured Clinical Inter-view for Diagnostic and Statistical Manual of Mental Disorders-Third Edition-Revised) of patients. Results: BPD patients cerebral blood flow differed from the controls' and showed corticolimbic dysfunction. Conclusion: As the dysfunction is compatible with the disorder's core symptoms, neuroimaging studies can contribute to the endo-phenotype studies which take into consider the clinical dimensions of BPD.

Özet

Amaç: Sınır kişilik bozukluğunun (SKB) tanı aşamasında Tek Foton Emisyon Bilgisayarlı Tomografi (SPECT) yöntemi ile görüntülemenin yerini değerlendirmektir. Yöntem: SCID-CV (Ruhsal Bozuklukların Tanısal ve Sayımsal El Kitabı, Dördüncü Baskıya göre Eksen I Bozuklukları için Yapılandırılmış Klinik Görüşme, Klinik Uyarlaması) ile değerlendirilen ve eş tanısı olmayan 20 SKB hastasının beyinlerinin dinlenme durumundaki kan akımları SPECT yöntemi ile görüntülenmiş, bu görüntüler 17 sağlıklı kontrolün beyin kan akımlarıyla karşılaş-tırılmıştır. Ayrıca hastaların SPECT görüntüleri, hastaların SCID-II (Ruhsal Bozuklukların Tanısal ve Sayımsal El Kitabı, Gözden Geçirilmiş Üçüncü Baskıya göre Kişilik Bozuklukları için Yapılandırılmış Klinik Görüşme) ile elde edilen klinik bulgularına göre de değerlendirilmiştir. Bulgular: SKB hastalarının beyin kan akımlarının kortiko-limbik yapılar arasında işlev bozukluğuna işaret edecek şekilde normal kontrollerden farklılık gösterdiği bulun-muştur. Sonuç: Bu değişikliklerin bozukluğun temel bulgularıyla da uyumlu olduğunun saptanması, SKB'nin klinik boyutları göz önüne alınarak yürütülen endofenotip araştırmalarına beyin görüntüleme çalışmalarının katkıda bulunabileceğini düşündürmektedir.

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Cite This Article

KÖSE, R., ABAY, E., ALTUN, D. G. (2010). Detection of regional blood flow in borderline personality disorder. Anadolu Psikiyatri Dergisi, Cilt: 11 - Sayı: 2, 102–111. https://ajindex.com/articles/356399

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