Journals / Anadolu Psikiyatri Dergisi / 2012 / Cilt: 13 - Sayı: 3

Sanrısal parazitozun tedavi seçenekleri: On dört hastalık olgu serisi

Treatment options of delusional parasitosis: case series of 14 patientsprivate

Pages
239–242
DOI
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Good remission rates can be achieved with first and second generation antipsychotics when compliance can be established. (Anatolian Journal of Psychiatry 2012; 13:239-242)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Delusional parasitosis (DP) is a rare psychiatric disorder in which patients develop the delusional belief that they are in- fested by parasites.
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Key Findings & Data:The remission rates for those on olanzapine were 71%, for those on risperidone were 50%.
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Conclusion & Impact:Good remission rates can be achieved with first and second generation antipsychotics when compliance can be established. (Anatolian Journal of Psychiatry 2012; 13:239-242)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Delusional parasitosis (DP) is a rare psychiatric disorder in which patients develop the delusional belief that they are in- fested by parasites. Second generation antipsychotics and antidepressants can be used for its treatment. Traditionally the first gener- ation antipsychotic pimozide has been used. The aim of this article is to investigate the efficacy of second generation antipsychotics compared to pimozide in a case series of patients with DP and to evaluate the validity of DP across cultures. Methods: We have evaluated fourteen patients with primary or secondary DP regarding their demographic and clinical variables as well as their re- sponses to treatment including chlorpromazine equivalent doses. We saw fourteen patients for a six month follow up period. Re- sults: Complete remission was achieved in all patients on pimozide therapy. The remission rates for those on olanzapine were 71%, for those on risperidone were 50%. The lowest doses in chlorpromazine equivalent doses to achieve full remission were used with olanzapine, followed by risperidone and pimozide. DP was found to be a valid diagnosis in the Turkish context. Discussion: Clinical and demographic data suggests that DP is a stable diagnostic category across different cultures. Good remission rates can be achieved with first and second generation antipsychotics when compliance can be established. (Anatolian Journal of Psychiatry 2012; 13:239-242)

Özet

Sanrısal parazitoz (SP) hastaların parazitlerle enfekte oldukları sanrısal inancını geliştirdikleri nadir görülen bir psikiyatrik bozukluktur. Tedavisi için ikinci kuşak antipsikotikler ve antidepresanlar kullanılabilir. Geleneksel olarak birinci kuşak antipsikotiklerden olan pimozid kullanılmıştır. SP tanısı konan olgu serisinde pimozide göre ikinci kuşak antipsikotik ilaçların etkinliğini araştırmak ve SPnin kültürler arasında geçerliliğini değerlendirmektir. Yöntem: Birincil veya ikincil SP tanısı konan 14 hastanın demografik ve klinik değişkenlerinin yanı sıra, klorpromazin eşdeğeri dozlarda tedaviye verdikleri yanıtlar değerlendirilmiştir. On dört hasta altı ay izlenmiştirSonuçlar: Pimozid alan tüm hastalar tam remisyona girmiştir. Olanzapin alanlarda remisyon oranı %71, risperidon alanlarda %50 olarak bulunmuştur. Tam remisyon elde etmek için kullanılan klorpromazin eşdeğeri dozlarda en düşük doz olanzapinde, ardından risperidon ve pimozidde kullanılmıştır. SP Türkiye bağlamında geçerli bir tanı olarak bulunmuştur. Tartışma: Klinik ve demografik veriler SP'nin farklı kültürler arasında tutarlı bir tanı kategorisi olduğunu göstermektedir. İyi bir uyum sağlandığında, hem birinci, hem de ikinci kuşak antipsikotiklerle iyi remisyon oranları elde edilebilir. (Anadolu Psikiyatri Derg 2012; 13:239-242)

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Cite This Article

COŞAR, B., TAŞKINOĞLU, K., LEEPING, P., BURHANOĞLU, S., ESER, H. Y., TANER, M. E., ARIKAN, Z. (2012). Sanrısal parazitozun tedavi seçenekleri: On dört hastalık olgu serisi. Anadolu Psikiyatri Dergisi, Cilt: 13 - Sayı: 3, 239–242. https://ajindex.com/articles/355878

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