Journals / Anestezi Dergisi / 2004 / Cilt: 12 - Sayı: 1

Comparison of sevoflurane and halothane on induction and recovery in pediatric patients

Sevofluran ve halotan ile indüksiyon ve derlenmenin pediatrik olgularda karşılaştırılması

Pages
23–27
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The utilisation of sevoflurane in the pediatric patiens may be safer than halothane in terms of having shorter recovery time and no laryngospasm during the induction.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, the effects of sevoflurane and halothane on induction and emergence and were compared.
📊
Key Findings & Data:The study enrolled 60 ASA I-II pediatric patients aged between 0-12 years.
💡
Conclusion & Impact:The utilisation of sevoflurane in the pediatric patiens may be safer than halothane in terms of having shorter recovery time and no laryngospasm during the induction.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Çocuk · Halotan · Karşılaştırmalı çalışma

Abstract

In this study, the effects of sevoflurane and halothane on induction and emergence and were compared. The study enrolled 60 ASA I-II pediatric patients aged between 0-12 years. They received no premedication and were randomized into two groups, one of which received sevoflurane anesthesia (S) and the other halothane anesthesia (H). Each of these volatile anesthetics were adminisrated in 33% oxygen and 67% nitrous-oxide mixture, in increasing doses. When the eye-lash reflex disappeared, the volatile anesthetic concentration was kept constant for four and a half minutes to complete the induction of anesthesia, until the patients were intubated. Following intubation, the volatile anesthetic dose was reduced to 1-1.5 MAC for maintenance. At the end of the surgical procedure, all volatile anesthetics vere stopped and 100% oxygen was administrated. During induction, the time between the beginning of the administration of the volatile anesthetic to the patient and the loss of the eye-lash reflex was recorded. During recovery, the time between the beginning of application of 100% oxygen and the first swallowing reflex, thefirst leg-pulling, the extubation time and the time ofcrying were noted. There were statistically significant difference the first leg-pulling times between the two groups. Laryngospasm was observed in two patients in Group H, vomiting was observed in one patient in Group H and 3 patients in Group S. The utilisation of sevoflurane in the pediatric patiens may be safer than halothane in terms of having shorter recovery time and no laryngospasm during the induction.

Özet

Bu çalışmada çocuk yaş grubunda sevofluran ile halotanın; indüksiyon ve derlenme dönemlerine etkilerinin karşılaştırılması amaçlandı. Premedikasyon uygulanmamış ASA I-II grubu, 0-12 yaşları arasında 60 çocuk, randomize olarak halotan (n=30) (H) ve sevofluran (n=30) grubu (S) olmak üzere iki gruba ayrıldı. Volatil anestezik her bir gruba tedrici olarak artırılarak %33 oksijen-%67 azot-protoksit karışımı ile birlikte uygulandı. Kirpik refleksi kaybolduktan sonra, volatil anestezik maddenin konsantrasyonu değiştirilmeden dörtbuçuk dakikalık indüksiyon süresini tamamlayarak hastalar entübe edildi. Entübasyon sonrasında volatil anestezik konsantrasyonu 1-1.5 MAC'lık idame değerine düşürüldü. Operasyonun son sütürlerinin konmaya başlanmasıyla birlikte tüm anestetik maddeler kesilerek %100 oksijen uygulanmaya başlandı. Maske tutulmasından kirpik refleksinin kaybolması, uyanma sırasında ilk yutkunma refleksi, ilk bacak çekme, ekstübasyon zamanı ve ilk ağlamaya başlayıncaya kadar geçen süreler kaydedildi, iki grup arasında bacak çekme süreleri arasında anlamlı farklılık vardı. Laringospazm H grubunda iki hastada gözlendi, kusma H grubunda bir, S grubunda ise 3 hastada tespit edildi. Sevofluranın pediyatrik hastalardaki kullanımının, indüksiyon sırasında laringospazm gözlenmemesi ve derlenme sürelerinin daha kısa olması nedenleriyle halotana oranla daha güvenilir olduğu kanısına varıldı.

🔖

Cite This Article

ŞERİFSOY, T. E., DEMİRARAN, Y., ÇELİKEL, N., KOCAMAN, B. (2004). Comparison of sevoflurane and halothane on induction and recovery in pediatric patients. Anestezi Dergisi, Cilt: 12 - Sayı: 1, 23–27. https://ajindex.com/articles/355599

References (15)

  1. Mushambi MC, Smith G. Inhalation anaesthetic agents. in: Aitkenhead AR Rowbotham DJ, Smith G (eds.) Textbook of anaesthesia, Spain, Churchill Livingstone 2001; 152-68
  2. Kayhan Z: Genel Anestezi. Klinik Anestezi. İstanbul, Logos yayıncılık, 1997;89-92
  3. Dudziak R, Vettermann J; Aufnahme.Verteilung und Metabolismus von Sevoflurane. Anaesthesist 1996; 45: 1-9
  4. Morgan Jr. G.E, Mikhail M.S: Clinical Anesthesiology USA (Stamford), Appleton&Lange 1996; 109-23
  5. Adachi M, İkemoto Y, Kubo K, Takuma C. Seizure-like move-ments during induction of anaesthesia with sevoflurane. Br J Anaesth 1992; 68: 214-5
  6. Ariftin SA. Whyte JA, Malins AF, Cooper GM. Comparison of induction and recovery betvveen sevoflurane and halothane supplementation of anaesthesia in children undergoing outpatient dental extractions. Br J Anaesth 1997: 78:157-9
  7. Goldberg ME, Larijani GE, Azad SS, et al. Comparison of tracheal intubating conditions and neuromuscular blocking profiles after intubuting doses of mivacurium chloride or succinylcholine in surgical outpatients. Anesth Analg 1989; 69:93-9
  8. Chiu CL, Chan YK, Ong G, Delilkan AE. A comparison of the induction and emergence characteristics of sevoflurane and halothane in children. Med J Malasia 1999; 54: 346-51
  9. Lerman J. Davis PJ, Welbom L et al. induction, recovery, and safety characteristics of sevoflurane in children undergoing ambulatory surgery. A comparison with halothane. Anesthesiology 1996; 8: 1332-40
  10. Epstein RH, Stein AL, Marr AT et al: High concentration versus incremental induction of anesthesia with sevoflurane in children: A comparison of induction times, vital signs, and complictions. J Clin Anesth 1998; 10:41-5
  11. Calderon E, Torres LM, Aguado JA et al: Comparative study of sevoflurane and nitrous oxide in pediatric anesthesia: efficacy and hemodynamic characteristics during induction. Rev Esp Anesthesiol Reanim 1998; 45:126-9
  12. Agnor RC, Sikich N, Lerman J: Single-breath vital capacity rapid inhalation induction in children: 8% sevoflurane versus 5% halothane. Anesthesiology 1998; 89: 379-84
  13. Kataria B, Epstein R, Bailey A et al: A comparison of sevoflurane to halothane in paediatric surgical patients: results of a multicentre international study. Paed Anaesth 1996; 6: 283-92
  14. Steinberg AL. Epstein RH, Mendel HG et al: Rapid versus slovv induction of general anesthesia with sevoflurane in children. Anesth Analg 1997; 84: 455
  15. Lerman J, Oyton JP, Gallagher TM et al: The minimum al