Journals / Anestezi Dergisi / 2003 / Cilt: 11 - Sayı: 3

Comparison of the sevoflurane and propofol with remifentanil in ambulatory surgery

Remifentanil kullanılan günübirlik hastalarda sevofluran ve propofol kullanımının karşılaştırılması

Pages
184–188
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion; early recovery of ambulatory surgery patients is significantly shorter after propofol with remifentanil compared to sevoflurane with remifentanil.

📌 3 Key Takeaways

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Objective & Hypothesis:We assesed induction properties, intraoperative hemodynamic responses and recovery profiles of propofol and sevoflurane using remifentanil for outpatient surgery.
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Key Findings & Data:After atropine 0.5 mg IV, all patients are received remifentanil 1 $mu$ g $kg^-1$ IV followed by 0.5 ug $kg^-1$ $min^-1$.
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Conclusion & Impact:In conclusion; early recovery of ambulatory surgery patients is significantly shorter after propofol with remifentanil compared to sevoflurane with remifentanil.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Propofol · Anestezi · ven içi

Abstract

We assesed induction properties, intraoperative hemodynamic responses and recovery profiles of propofol and sevoflurane using remifentanil for outpatient surgery. After atropine 0.5 mg IV, all patients are received remifentanil 1 $mu$ g $kg^-1$ IV followed by 0.5 ug $kg^-1$ $min^-1$. Patients in Group I (n=25) received %8 sevoflurane via mask; whereas patients in Group II (n=25) received propofol 2 $mg^-1$ $kg^-1$ IV, followed by 9 $mg^-1$ $kg^-1$ $hr^-1$. Five minutes after skin incision, infusion rates were decreased (sevoflurane to end-tidal %1, remifentanil to 0.25 $mu$ $g^-1$ $kg^-1$ $min^-1$ and propofol to 6 $mg^-1$ $kg^-1$ $hr^-1$). At the end of surgery all infusions were discontinued. Blood pressure and heart rate were recorded before induction, before and after intubation and incision every 5 min intraoperatively. At the end of surgery, remifentanil, propofol and sevoflurane were discontinued, recovery times, postoperative pain scores and side effects were recorded. Times to spontaneous respiration was longer in Group II whereas times for response to verbal commands and Aldrete score $geq$ 9 were longer in Group I (p<0.05). Pain scores were higher in Group II (p<0.05). Times to able to ambulate and PADS were $geq$ 9 longer in Group II (p<0.05). In conclusion; early recovery of ambulatory surgery patients is significantly shorter after propofol with remifentanil compared to sevoflurane with remifentanil.

Özet

Bu çalışmada, günübirlik cerrahi planlanan hastalarda, remifentanil ile sevofluran veya propofolün indüksiyon, intraoperatif hemodinamik yanıt ve postoperatif derlenme özelliklerinin karşılaştırılması amaçlandı. Varikosel cerrahisi planlanan, 18-50 yaş arası 50 olguya atropin 0,5 mg İV'den sonra remifentanil 1 $mu$ $kg^-1$ IV uygulandı ve 0.5 [tg $kg^-1$ $dk^-1$ remifentanil infüzyonu başlandı. I. Gruba (n=25) %100 O2 içerisinde %8 konsantrasyonda sevofluran maske yolu ile uygulandı. U.Gruba (n=25) 2 mg $kg^-1$ propofol IVsonrası, 9 mg $kg^-1$ sf'propofol infüzyonu ayrı bir IV yoldan başlandı. Her iki grupta atrakuryum 0.5 mg $kg^-1$ IV verildikten 2 dk sonra intübasyon gerçekleştirildi. Insizyondan 5 dk sonra remifentanil infüzyon dozu 0.25 $mu$g $kg^-1$ dk1 , sevofluran end-tidal konsantrasyonu % l'e (0.5 MAC), propofol infüzyon dozu 6 mg $kg^-1$ $st^-1$ 'e düşürüldü, indüksiyon öncesi, intübasyon sonrası ve insizyondan l ve 5 dk sonra, cerrahi süresince 5 dk ara ile kan basıncı, kalp atım hızı kaydedildi. Cerrahi bitiminde remifentanil, propofol ve sevofluran uygulaması sonlandırıldı, derlenme süreleri, postoperatif ağrı skorları ve yan etkiler kaydedildi. Spontan ventilasyon başlama süresi II. Grupta, sözlü komutlara yanıt ve Aldrete skoru $geq$ 9 olma süreleri I. Grupta daha uzundu (p<0.05). Postoperatif ağrı skorları II. Grupta daha yüksek seyretti (p<0.05). Yardımsız ambulasyon ve eve gönderilme (PADS $geq$ 9) süreleri II.Grupta daha uzun bulundu (p<0.05). Sonuç olarak, remifentanil infüzyonu uygulanan günübirlik olgularda propofol ile TIVA'nın, sevofluran ile inhalasyon anestezisine göre daha hızlı derlenme sağladığı kanısına varıldı.

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Cite This Article

SAKLIYAN, M., ERHAN, E., ALPER, I., UĞUR, G., ÖZYAR, B. (2003). Comparison of the sevoflurane and propofol with remifentanil in ambulatory surgery. Anestezi Dergisi, Cilt: 11 - Sayı: 3, 184–188. https://ajindex.com/articles/355309

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