Journals / Anestezi Dergisi / 2003 / Cilt: 11 - Sayı: 2

Comparison of desflurane and isoflurane anaesthesias on the awakening and recovery scores in outpatient arthroscopic surgery

Günübirlik artroskopik cerrahide desfluran ve izofluran anestezilerinde uyanma ve derlenme skorlarının karşılaştırılması

Pages
105–110
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Desflurane seems to be a proper agent for outpatient anaesthesia procedures.

📌 3 Key Takeaways

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Objective & Hypothesis:Due to their pharmacokinetic properties, volatile agents are the anaesthetics of choice in outpatient anaesthesia.
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Key Findings & Data:Fifty-one patients (desflurane n=33, isoflurane n=18) scheduled for arthroscopic knee surgery were enrolled in this prospective randomized study.
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Conclusion & Impact:Desflurane seems to be a proper agent for outpatient anaesthesia procedures.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İzofluran · Günübirlik cerrahi işlemler · Anestezikler

Abstract

Due to their pharmacokinetic properties, volatile agents are the anaesthetics of choice in outpatient anaesthesia. Our aim is to find an answer for the question "Is desflurane ideal for outpatient anaesthesia" and to compare isoflurane with the most recent agent desflurane evaluating its effect profile. Fifty-one patients (desflurane n=33, isoflurane n=18) scheduled for arthroscopic knee surgery were enrolled in this prospective randomized study. Pulse rates, blood pressures, inspired and end-tidal concentrations of the anaesthetic agents were recorded during anaesthesia. Times for cough reflex, extubation, eyelash reflex, eye opening to verbal stimulus, recovery and discharge scores were measured. Inhalation agents are used in similar concentrations in our study (0.53 MAC for both agents). Desflurane's onset and emergence of anaesthesia is faster than isoflurane. Duration of anaesthesia has no effect on awakening, recovery and discharge times in short outpatient anaesthesia procedures. The age of the patient effects only the recovery time. The patients completed the recovery scores and discharge scores faster in the desflurane group compared to isoflurane, times for cough reflex, extubation and eye opening were also faster. Desflurane seems to be a proper agent for outpatient anaesthesia procedures.

Özet

İnhalasyon anestezikleri, uygun farmakokinetik özellikleri nedeniyle günübirlik anestezide tercih edilmektedir. Biz bu çalışmada, ülkemizde en yeni olarak kullanılmaya başlanan desfluranı, izofluran ile karşılaştırarak etki profilini değerlendirmek ve "günübirlik anestezide desfluran ideal bir ajan mıdır?" sorusuna yanıt aramayı amaçladık. Prospektif randomize planlanan bu çalışmaya artroskopik menisküs onarımı yapılacak 51 hasta (desfluran n=33, izofluran n=18) alındı. Anestezi süresince hastaların kalp atım hızı, kan basıncı, anestezik ajanların inspire edilen ve end-tidal konsantrasyonları kaydedildi. Anestezi bitiminde öksürük refleks zamanı, ekstübasyon zamanı, kirpik refleks zamanı, sözlü uyarana göz açma yanıt zamanı, anestezi sonrası derlenme ve taburculuk skorları ölçüldü. İnhalasyon ajanlarının benzer düzeyde kullanıldığı çalışmamızda (her iki ajan için 0.53 MAC) desfluranm, izoflurana göre etkisinin başlaması ve bitmesi hızlı olmuştur. Hastaların uyanma, derlenme ve taburcu süreleri üzerinde anestezi süresinin etkisiz olduğu, hasta yaşının sadece derlenme süresini etkilediği gözlenmiştir. Desfluran grubunun öksürük refleksi zamanı, ekstübasyon zamanı ve göz açma yanıt zamanı, derlenme ve taburcu olma süresi izofluran grubuna göre çok daha kısadır. Sonuç olarak, desfluranm günübirlik anestezi şartlarında kullanım için uygun bir ajan olduğu düşüncesindeyiz.

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Cite This Article

ARIK, E., YAZICIOĞLU, D., ÜLKER, A., ÖZKAN, D., POLAT, U., GÜMÜŞ, H. (2003). Comparison of desflurane and isoflurane anaesthesias on the awakening and recovery scores in outpatient arthroscopic surgery. Anestezi Dergisi, Cilt: 11 - Sayı: 2, 105–110. https://ajindex.com/articles/355288

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