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Journals / Anestezi Dergisi / 2007 / Cilt: 15 - Sayı: 2

Profol infusion syndrome

Profol infüzyon sendromu

Hülya ÇELEBİ
Nur CANDAN
Berrin GÜNAYDIN
Pages
73–80
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Due to widespread use of propofol in the non-anesthetic field, we suggest the cautious use of long term propofol for sedation in children and adults until the pathophysiology is clarified.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This review presents the propofol infusion syndrome related to high doses and long term propofol use, which is characterized by metabolic acidosis, life-threatening dysrhythmias, heart failure, rhabdomyolysis and renal failure.
📊
Key Findings & Data:Case reports, reviews published between 1990 and 2006, and the reports of the regulatory centers and manufacturers were examined within the scope of this study.
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Conclusion & Impact:Due to widespread use of propofol in the non-anesthetic field, we suggest the cautious use of long term propofol for sedation in children and adults until the pathophysiology is clarified.
🔬Design:Review & Systematic Survey
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

This review presents the propofol infusion syndrome related to high doses and long term propofol use, which is characterized by metabolic acidosis, life-threatening dysrhythmias, heart failure, rhabdomyolysis and renal failure. Case reports, reviews published between 1990 and 2006, and the reports of the regulatory centers and manufacturers were examined within the scope of this study. Due to widespread use of propofol in the non-anesthetic field, we suggest the cautious use of long term propofol for sedation in children and adults until the pathophysiology is clarified.

Özet

Bu derlemede metabolik asidoz, hayatı tehdit eden disritmiler, kalp yetmezliği, rabdomiyoliz ve renal yetmezlikle karakterize olan propofolün yüksek doz ve uzun süre kullanımıyla ilişkili Propofol infüzyon Sendromu; 1990-2006 tarihleri arasında yayınlanan olgular, derlemeler, denetleyici merkezlerin ve üretici firmanın görüşleri incelenerek sunuldu. Propofolün anestezi dışında gittikçe genişleyen kullanım alanları nedeniyle karşılaşılan bu sorunun sebebi tam olarak anlaşılana kadar çocuk ve erişkin yoğun bakım hastalarının sedasyonunda uzun süreli infüzyon şeklinde kullanılmasının sakıncalı olabileceğine dikkat çekilmek istendi.

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Cite This Article

ÇELEBİ, H., CANDAN, N., GÜNAYDIN, B. (2007). Profol infusion syndrome. Anestezi Dergisi, Cilt: 15 - Sayı: 2, 73–80. https://ajindex.com/articles/355242

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