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Journals / Anestezi Dergisi / 2015 / Cilt: 23 - Sayı: 1

SUGAMMADEX: A NEW APPROACH IN THE REVERSAL OF NEUROMUSCULAR BLOCKADE

SUGAMMADEKS: NÖROMÜSKÜLER BLOĞUN GERİ ÇEVRİLMESİNDE YENİ BİR YAKLAŞIM

Şennur YÜCE
Yücel YÜCE
Pages
4–10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, a detailed information about neuromuscular blockageand sugammadeks was given

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Nowadays, the procedure to speed the neuromuscular recovery is enabled by the use of anticholinesterases which interactwith the acetylcholin degradation and which speed the neuromuscular transmission.
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Key Findings & Data:Sugammadeks is a member of ?-cyclodextringroup which is newly found for the neuromuscular reversal, is a molecule which has 8 glucose rings.
💡
Conclusion & Impact:In this review, a detailed information about neuromuscular blockageand sugammadeks was given
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Nowadays, the procedure to speed the neuromuscular recovery is enabled by the use of anticholinesterases which interactwith the acetylcholin degradation and which speed the neuromuscular transmission. Sugammadeks is a member of ?-cyclodextringroup which is newly found for the neuromuscular reversal, is a molecule which has 8 glucose rings. It binds to rocuronium in aratio of 1:1 and it decreases its plasma concentration to zero. In this review, a detailed information about neuromuscular blockageand sugammadeks was given

Özet

Günümüzde nöromusküler derlenmeyi hızlandırma işlemi asetilkolinin yıkımıyla etkileşen ve nöromusküler transmisyonuhızlandıran antikolinesterazların uygulanmasıyla sağlanmaktadır. Nöromusküler bloğun geri çevrilmesinde en son geliştirilensugammadeks, ?-siklodekstrin grubundan 8 şeker halkasına sahip bir moleküldür. Rokuronyum ile 1:1 oranında bağlanır ve aktifplazma konsantrasyonunu sıfıra düşürür. Bu derlemede nöromusküler blokaj ve sugammadeks hakkında detaylı bilgi verilmeyeçalışıldı

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Cite This Article

YÜCE, Ş., YÜCE, Y. (2015). SUGAMMADEX: A NEW APPROACH IN THE REVERSAL OF NEUROMUSCULAR BLOCKADE. Anestezi Dergisi, Cilt: 23 - Sayı: 1, 4–10. https://ajindex.com/articles/355184

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