Journals / ANKEM Dergisi / 2009 / Cilt: 23 - Sayı: 3

The effect of oral microbiota on general health

Ağız mikroflorasının genel sağlığa etkisi

Pages
137–145
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The mouth is a significant contributor to both the total burden of infection and the total burden of inflammation and, hence, to overall health and well-being.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The oral microflora is extremely diverse and unique.
📊
Key Findings & Data:According to new sequencing technology, it harbors >19,000 phylotypes.
💡
Conclusion & Impact:The mouth is a significant contributor to both the total burden of infection and the total burden of inflammation and, hence, to overall health and well-being.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The oral microflora is extremely diverse and unique. According to new sequencing technology, it harbors >19,000 phylotypes. They are mostly commensal species and form mixed biofilms. Their behavior can be very dynamic, adapting to a wide range of environments. They can become pathogenic by changing profiles of expressed genes in responses to environmental changes. The mouth is a significant contributor to both the total burden of infection and the total burden of inflammation and, hence, to overall health and well-being. Periodontitis is a bacterially induced, localized, chronic inflammatory disease. Periodontitis has been widely reported to be associated with an increase in the systemic inflammatory response, and has emerged as a possible risk factor for atherosclerosis and cardiovascular diseases over the last decade. It is vital in raising the awareness of oral health and general health issues at both individual and community levels.

Özet

Ağız mikroflorası son derece karmaşık ve eşsizdir. Yeni sekanslama teknolojisine göre >19,000 Şlotip barındırmaktadır. Bunların çoğu kommensal türlerdir ve karmaşık biyofilmler oluştururlar. Son derece dinamiktirler ve çok çeşitli çevrelere adapte olabilirler. Çevresel değişikliklere yanıt olarak eksprese ettikleri gen profilini değiştirerek patojen hale gelebilirler. Ağızın hem infeksiyon hem inflamasyona ve dolayısıyla genel sağlık ve iyilik haline katkısı çok önemlidir. Periodontitis bir bakteri infeksiyonu olarak başlayan, lokal, kronik inflamatuvar hastalıktır. Periodontitisin sistemik inflamatuvar yanıtı artırdığı ve ateroskleroz ve kardiovasküler hastalıkların olası bir risk faktörü olduğu konusunda son on yıldır kanıtlar artmıştır. Ağız sağlığı ve genel sağlık ilişkisi konusunda hem kişisel hem toplumsal düzeyde farkındalık artırılması yaşamsaldır.

🔖

Cite This Article

KÜLEKÇİ, G., GÖKBUGET, A. (2009). The effect of oral microbiota on general health. ANKEM Dergisi, Cilt: 23 - Sayı: 3, 137–145. https://ajindex.com/articles/355024

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Aas JA, Paster BJ, Stokes LN, Olsen I, Dewhirst FE: Defining the normal bacterial flora of the oral cavity, J Clin Microbiol 2005;43(11):5721-32
  2. American Academy of Periodontology: Assess your risk of gum disease, http://www.perio.org (2009)
  3. Avila M, Ojcius DM, Yilmaz Ö: The oral microbiota: Living with a permanent guest, DNA Cell Biol 2009;28(8):405-11
  4. Barnett ML: The oral-systemic disease connection: An update for the practicing dentist, J Am Dent Assoc 2006;137(Suppl):5S-6S
  5. CampS, Lei Y, Costalonga M et al: Systemic disease and the oral microbiota, “Lamont RJ, Burne RA, Lantz MS, Leblanc DJ (eds): Oral Microbiology and Immunology” kitabında s.361-75, ASM Press Washington (2006)
  6. Costalonga M, Hodges JS, Herzberg MC: Streptococcus sanguis modulates type II collageninduced arthritis in DBA/1J mice, J Immunol 2002;169(4):2189-95
  7. Dewhirst FE, Izard J, Paster BJ et al: The Human Oral Microbiome Database, http://www.HOMD. org (2008)
  8. Ford PJ, Gemmell E, Timms P, Chan A, Preston FM, Seymor GJ: Anti-P.gingivalis response correlates with atherosclerosis, J Dent Res 2007;86(1):35-40
  9. Friedewald VE, Kornman KS, Beck JD et al: American Journal of Cardiology; Journal of Periodontology: The American Journal of Cardiology and Journal of Periodontology Editors’ Consensus: Periodontitis and atherosclerotic cardiovascular disease, Am J Cardiol 2009;104(1):59-68
  10. Gökalp S, Güçiz Doğan B, Tekçiçek M, Berberoğlu A, Ünlüer Ş: Beş, oniki ve onbeş yaş çocuklarının ağız-diş sağlığı profili, Türkiye-2004, Hacettepe Dişhek Fak Derg 2007;31(4):3-10
  11. Gökalp S, Güçiz Doğan B, Tekçiçek M, Berberoğlu A, Ünlüer Ş: Erişkin ve yaşlılarda ağız-diş sağlığı profili, Türkiye-2004, Hacettepe Dişhek Fak Derg 2007;31(4):11-8
  12. Gregory J, Seymour GJ, Ford PJ et al: Infection or inflammation: The link between periodontal and cardiovascular diseases, Future Cardiology 2009;5(1):5-9
  13. Hasturk H, Kantarci A, Goguet-Surmenian E et al: Resolvin E1 regulates inflammation at the cellular and tissue level and restores tissue homeostasis in vivo, J Immunol 2007;179(10):7021-9
  14. Keijser BJ, Zaura E, Huse SM et al: Pyrosequencing analysis of the oral microflora of health adults, J Dent Res 2008;87(11):1016-20
  15. Lopez-Garcia P, Moreira D: Tracking microbial biodiversity through molecular and genomic ecology, Res Microbiol 2008;159(1):67-73
  16. Mayo JA, Zhu H, Harty DW, Knox KW: Modulation of glycosidase and protease activities by chemostat growth condition