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Journals / Acta Orthopaedica et Traumatologica Turcica / 2017 / Cilt: 51 - Sayı: 2

The effects of intra-articular levobupivacain versus levobupivacain plus magnesium sulfate on postoperative analgesia in patients undergoing arthroscopic meniscectomy: A prospective randomized controlled study

NURCAN KIZILCIK
TURHAN ÖZLER
Ferdi MENDA
Çağatay ULUÇAY
Özge KÖNER
Faik ALTINTAŞ
Pages
104–109
DOI
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This isan open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Objective & Hypothesis:Objective: The aim of this study was to compared the effectiveness of intraarticular levobupivacain withlevobupivacain and magnesium sulfate.Methods: In this prospective randomized double blinded study, 96 patients (67 male, 29 female; agerange: 18e65 years) with ASA (American Society of Anesthesiologist) score I and II, who had undergonearthroscopic meniscectomy operation, were divided to 3 groups that had postoperative analgesia withintra-articular saline injection (control group), levobupivacain injection (L group) or levobupivacain andmagnesium sulfate injection (LM group).
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Key Findings & Data:Patients were compared with postoperative VAS (Visual AnalogScore) score during rest and activity, opioid analgesic need, non-opioid analgesic need and othermedication needs.Results: Postoperative VAS scores during rest and activation at early postoperative period were signiŞcantly lower at LM group when compared with L group and lower than control group at all time periods.Opioid analgesic need, non-opioid analgesic need and other medication needs for non-pain symptomswere lower at LM group when compared with L and control groups at all time periods.Conclusion: Intraarticular magnesium sulfate plus Levobupivacain injection is a safe and effectivemethod for post operative pain management after arthroscopic meniscectomy.Keywords: Intra-articular injection, Magnesium sulfate, Levobupivacain, Postoperative analgesia, Chondrocyte apoptosis, Pain management, Arthroscopic menisectomyLevel of Evidence: Level I, Therapeutic study© 2017 Turkish Association of Orthopaedics and Traumatology.
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Conclusion & Impact:This isan open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to compared the effectiveness of intraarticular levobupivacain withlevobupivacain and magnesium sulfate.Methods: In this prospective randomized double blinded study, 96 patients (67 male, 29 female; agerange: 18e65 years) with ASA (American Society of Anesthesiologist) score I and II, who had undergonearthroscopic meniscectomy operation, were divided to 3 groups that had postoperative analgesia withintra-articular saline injection (control group), levobupivacain injection (L group) or levobupivacain andmagnesium sulfate injection (LM group). Patients were compared with postoperative VAS (Visual AnalogScore) score during rest and activity, opioid analgesic need, non-opioid analgesic need and othermedication needs.Results: Postoperative VAS scores during rest and activation at early postoperative period were signiŞcantly lower at LM group when compared with L group and lower than control group at all time periods.Opioid analgesic need, non-opioid analgesic need and other medication needs for non-pain symptomswere lower at LM group when compared with L and control groups at all time periods.Conclusion: Intraarticular magnesium sulfate plus Levobupivacain injection is a safe and effectivemethod for post operative pain management after arthroscopic meniscectomy.Keywords: Intra-articular injection, Magnesium sulfate, Levobupivacain, Postoperative analgesia, Chondrocyte apoptosis, Pain management, Arthroscopic menisectomyLevel of Evidence: Level I, Therapeutic study© 2017 Turkish Association of Orthopaedics and Traumatology. Publishing services by Elsevier B.V. This isan open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Cite This Article

KIZILCIK, N., ÖZLER, T., MENDA, F., ULUÇAY, Ç., KÖNER, Ö., ALTINTAŞ, F. (2017). The effects of intra-articular levobupivacain versus levobupivacain plus magnesium sulfate on postoperative analgesia in patients undergoing arthroscopic meniscectomy: A prospective randomized controlled study. Acta Orthopaedica et Traumatologica Turcica, Cilt: 51 - Sayı: 2, 104–109. https://ajindex.com/articles/354391

References (2)

  1. Elvir-Lazo OL, White PF. The role of multimodal analgesia in pain management after ambulatory surgery. Curr Opin Anaesthesiol. 2010;23:697e703. Benyamin R, Trescot AM, Datta S, et al. Opioid complications and side effects. Pain Physician. 2008;11:105e120. Ayoglu H, Altunkaya H, Bayar A, Turan IO. The effect of intraarticular combi- nations of tramadol and ropivacaine with ketamine on postoperative pain after arthroscopic meniscectomy. Arch Orthop Trauma Surg. 2010;130:307e312. Lo IK, Sciore P, Chung M, Liang S. Local anesthetics induce chondrocyte death in bovine articular cartilage disks in a dose- and duration-dependent manner. Arthroscopy. 2009;25:707e715. Gungor I, Yilmaz A, Ozturk AM, Ergun MA. Bupivacaine and levobupivacaine induce apoptosis in rat chondrocyte cell cultures at ultra-low doses. Eur J Orthop Surg Traumatol. 2014;24:291e295. Hoofwijk DM, Fiddelers AA, Emans PJ, et al. Prevalence and predictive factors of chronic postsurgical pain and global surgical recovery 1 Year after outpatient knee arthroscopy: a prospective cohort study. Med Baltim. 2015;94:e2017. Gristwood RW. Cardiac and CNS toxicity of levobupivacaine: strengths of evi- dence for advantage over bupivacaine. Drug Saf. 2002;25:153e163. Lykoudi I, Kottis G, Nikolaou VS, Setaki P, Fassoulaki A, Efstathopoulos N. Intra- articular morphine enhances analgesic efŞcacy of ropivacaine for knee arthroscopy in ambulatory patients. Orthopedics. 2011;34:91e102. Koltka K, Koknel-Talu G, Asik M, Ozyalcin S. Comparison of efŞcacy of intra- articular application of magnesium, levobupivacaine and lornoxicam with placebo in arthroscopic surgery. Knee Surg Sports Traumatol Arthrosc. 2011;19: 1884e1889. Mitra S, Kaushal H, Gupta RK. Evaluation of analgesic efŞcacy of intra-articular bupivacaine, bupivacaine plus fentanyl, and bupivacaine plus tramadol after arthroscopic knee surgery. Arthroscopy. 2011;27:1637e1643. Chen Y, Zhang Y, Zhu YL, Fu PL. EfŞcacy and safety of an intra-operative intra- articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2012;40:2032e2040.
  2. Campo MM, Kerkhoffs GM, Sierevelt IN, Weeseman RR. A randomised controlled trial for the effectiveness of intra-articular Ropivacaine and Bupi- vacaine on pain after knee arthroscopy. Knee Surg Sports Traumatol Arthrosc. 2012;20:239e244. Al-Metwalli RR, MowaŞ HA, Ismail SA, Siddiqui AK. Effect of intra-articular dexmedetomidine on postoperative analgesia after arthroscopic knee sur- g