Journals / Acta Orthopaedica et Traumatologica Turcica / 2011 / Cilt: 45 - Sayı: 1

Preoperative hematological assessment of pediatric patients with cerebral palsy

Serebral palsili çocuk hastalarda ameliyat öncesi hematolojik değerlendirme

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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Advanced preoperative hematological tests can only be recommended for CP patients with abnormal blood test results.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Nutritional deficiencies and use of antiepileptic drugs can lead to alterations in the hematological status of children with cerebral palsy (CP), which may increase the risk of intra operative or postoperative hematological complications.
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Key Findings & Data:Methods: Hemoglobin level, hematocrit, red blood cell count, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red cell distribution width, white blood cell count, platelet count, prothrombin time, activated partial thromboplastin time, and plasma fibrinogen concentration were compared between 62 consecutive CP patients [28 girls, 34 boys; mean age 8.8 years (range 2-16 years)] and 130 consecutive orthopedic patients as control [64 girls, 66 boys; mean age 9.2 years (range 2-16 years)] who did not have any skeletal, cranial, thoracic, abdominal or major soft tissue injuries, or any other infectious, metabolic, hema- tological or malignant tumor disorders.
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Conclusion & Impact:Advanced preoperative hematological tests can only be recommended for CP patients with abnormal blood test results.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hematolojik testler · Kan kaybı · cerrahi

Abstract

Objectives: Nutritional deficiencies and use of antiepileptic drugs can lead to alterations in the hematological status of children with cerebral palsy (CP), which may increase the risk of intra operative or postoperative hematological complications. In this retrospective study, we evaluat ed the preoperative routine blood tests of CP patients with different levels of walking ability, who were scheduled to undergo orthopedic procedures. Methods: Hemoglobin level, hematocrit, red blood cell count, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red cell distribution width, white blood cell count, platelet count, prothrombin time, activated partial thromboplastin time, and plasma fibrinogen concentration were compared between 62 consecutive CP patients [28 girls, 34 boys; mean age 8.8 years (range 2-16 years)] and 130 consecutive orthopedic patients as control [64 girls, 66 boys; mean age 9.2 years (range 2-16 years)] who did not have any skeletal, cranial, thoracic, abdominal or major soft tissue injuries, or any other infectious, metabolic, hema- tological or malignant tumor disorders. Results: CP and control groups were similar with regard to the above-mentioned hematological parameters. In the CP group, no difference was found between Gross Motor Function Classification System for Cerebral Palsy (GMFCS) level I/II patients and GMFCS level III/IV patients in terms of these hematological parameters. Conclusion: Preoperative blood tests results of pediatric CP patients, walking with or without any supportive devices and undergoing orthopedic interventions, are similar to those of other orthopedic patients. Advanced preoperative hematological tests can only be recommended for CP patients with abnormal blood test results.

Özet

Amaç: Beslenme bozuklukları ve antiepileptik ilaç kullanımı serebral palsili (SP) çocukların hematolojik tablosunda değişimlere yol açabilmekte ve bu değişimler ameliyat sırasında ya da sonrasında hematolojik komplikasyon görülme riskini artırabilmektedir. Bu retrospektif çalışmada, değişik derecelerde yürüme yeteneği olan ve ortopedik girişim geçirmesi planlanan SP'li çocuk hastaların ameliyat öncesi rutin kan testlerinin değerlendirilmesi amaçlanmıştır. Çalışma planı: Ortalama yaşı 8.8 (dağılım 2-16) olan 62 ardışık SP'li hastanın (28 kız, 34 erkek) hemoglobin, hematokrit, kırmızı kan hücresi sayımı, ortalama korpusküler hacim, ortalama korpusküler hemoglobin, ortalama korpusküler hemoglobin konsantrasyonu, kırmızı hücre dağılımı genişliği, beyaz kan hücresi sayımı, trombosit sayımı, protrombin zamanı, aktive parsiyel tromboplastin zamanı ve plazma fibrinojen konsantrasyonu değerleri; kontrol grubu olarak ortalama yaşı 9.2 (dağılım 2-16) olan ve herhangi birkemik, kafa, göğüs, batın ya da majör yumuşak doku travma öyküsü ve enfeksiyöz, metabolik, hematolojik hastalık ya da kötü huylu tümör öyküsü olmayan 130 ardışık ortopedi hastasının (64 kız, 66 erkek) değerleriyle karşılaştırıldı. Bulgular: SP ve kontrol grupları arasında yukarıda belirtilen hematolojik değişkenler açısından anlamlı fark bulunmadı. Ayrıca, SP grubunda Gross Motor Fonksiyon Sınıflama Sistemi (GMFSS) evre I/II olgular ile GMFSS evre III/IV olgular hematolojik bulgular açısından fark göstermedi. Çıkarımlar: Destekli ya da desteksiz yürüyebilen ve ortopedik girişim planlanan SP'li çocuk hastaların ameliyat öncesi rutin kan testleri diğer ortopedi hastalarının rutin kan testleriyle benzerdir. Bu grup SP'li hastalarda daha ileri hematolojik tetkiklerin yapılması ancak rutin testlerde anormal bir duruma rastlanması halinde önerilebilir.

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Cite This Article

ÖMEROĞLU, H., İNAN, U., TURGUT, K., HARMANŞA, S. (2011). Preoperative hematological assessment of pediatric patients with cerebral palsy. Acta Orthopaedica et Traumatologica Turcica, Cilt: 45 - Sayı: 1, 1–5. https://ajindex.com/articles/354087

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