Journals / Ağrı / 2013 / Cilt: 25 - Sayı: 4

A new anagesic drug: Pregabalin; and the first intoxications

Yeni bir ağrı kesici: Pregabalin ve ilk zehirlenmeler

Journal
Ağrı
Pages
187–189
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

But, it is to be noted that either the kidneys of the patients are in good functioning state or there is a hemodialysis facility in the immediate vicinity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pregabalin is an antiepileptic, analgesic and anxiolytic drug that GABA analogue with similar structure and actions to gabapentin.
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Key Findings & Data:A 24-year-old male presented following ingestion of 3 g of pregabalin in this report.
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Conclusion & Impact:But, it is to be noted that either the kidneys of the patients are in good functioning state or there is a hemodialysis facility in the immediate vicinity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Pregabalin is an antiepileptic, analgesic and anxiolytic drug that GABA analogue with similar structure and actions to gabapentin. There are very few reports about pregabalin intoxication in the literature. A 24-year-old male presented following ingestion of 3 g of pregabalin in this report. He was managed with General Supportive Care and Symptomatic Approach (GSCSA) such as discontinuation of the drug, hydration with IV fluids, oxygenation, gastric lavage and activated charcoal administration and enhanced elimination techniques. But, it is to be noted that either the kidneys of the patients are in good functioning state or there is a hemodialysis facility in the immediate vicinity.

Özet

Pregabalin gabapentinle aynı yapı ve etkiye sahip, GABA analogu, antiepileptik, analjezik ve anksiyolitik bir ilaçtır. Literatürde pregabalin zehirlenmesine ait çok az sayıda bildiri vardır. Bu yazıda, 3 gram pregabalin içen 24 yaşındaki erkek hastayı sunduk. Hasta ilacın uzaklaştırılması, intravenöz sıvı tedavisi, oksijenizasyon, mide yıkama, aktif kömür uygulaması gibi Genel Destek Tedavisi ve Semptomatik Yaklaşım (GDTSY) ile tedavi edildi. Ancak ya hastaların böbreklerinin iyi çalışır durumda olması ya da hemodiyaliz imkanının çok yakınlarda bulunması gerekliliği unutulmamalıdır.

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Cite This Article

BELLİ, E., ERKALP, K., YANGIN, Z., FADILLIOĞLU, S., ALAGÖL, A. (2013). A new anagesic drug: Pregabalin; and the first intoxications. Ağrı, Cilt: 25 - Sayı: 4, 187–189. https://ajindex.com/articles/353325

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