Journals / Gülhane Tıp Dergisi / 2021 / Cilt: 63 - Sayı: 2

Sleep disorders in multiple sclerosis

Pages
141–146
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: Our results show that half of the patients with MS suffer from sleep disorders.

📌 3 Key Takeaways

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Objective & Hypothesis:Aims: Previous studies have reported that sleep disorders are frequently seen in patients with multiple sclerosis (MS).
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Key Findings & Data:Results: Fifty-six patients [age (mean±standard deviation): 36.2±2.8 years; female: 30.4%] were included.
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Conclusion & Impact:Conclusions: Our results show that half of the patients with MS suffer from sleep disorders.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Aims: Previous studies have reported that sleep disorders are frequently seen in patients with multiple sclerosis (MS). In this study, we aimed to investigate the frequency and related factors of sleep disorders in these patients. Methods: In this cross-sectional study, sleep disorder was assessed using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS). Fatigue, generalized pain, anxiety, depression symptoms, restless legs syndrome (RLS) and urinary dysfunction were evaluated using the Fatigue Severity Scale (FSS), visual analogue scale (VAS), Hospital Anxiety and Depression Scale (HAD), and RLS Rating Scale and Scales for Outcomes in Parkinson’s diseaseAutonomic. Logistic regression analysis was used to assess the potential associations between a sleep disorder diagnosis and the investigated conditions. Results: Fifty-six patients [age (mean±standard deviation): 36.2±2.8 years; female: 30.4%] were included. Fifty percent of the patients scored 5 or more according to PSQI. ESS, HADS, FSS and VAS scores of patients with sleep disorder were significantly higher than those of patients with no sleep disorder (p=0.002, p=0.001, p<0.001, and p<0.001, respectively). Logistic regression analysis showed significant associations between sleep disorder and fatigue [Odds ratio (OR): 6.54 (95% confidence interval (CI): 1.08-39.57, p=0.041)], depression [OR: 9.82 (95% CI: 1.47- 65.6), p=0.018], and generalized pain disorders [OR: 1.79 (95% CI: 1.23-2.3), p=0.002]. Conclusions: Our results show that half of the patients with MS suffer from sleep disorders. Sleep disorders in this group are associated with fatigue, depression, daytime sleepiness, common body pain, and immunomodulatory treatment.

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Cite This Article

AKIN, Y. A., POLAT, B. S. A. (2021). Sleep disorders in multiple sclerosis. Gülhane Tıp Dergisi, Cilt: 63 - Sayı: 2, 141–146. https://ajindex.com/articles/347973

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References (17)

  1. Coles A. Multiple sclerosis. Pract Neurol. 2009;9:118-126
  2. Tachibana N, Howard RS, Hirsch NP, Miller DH, Moseley IF, Fish D. Sleep problems in multiple sclerosis. Eur Neurol. 1994;34:320-323
  3. Bamer AM, Johnson KL, Amtmann D, Kraft GH. Prevalence of sleep problems in individuals with multiple sclerosis. Mult Scler. 2008;14:1127-1130
  4. Fleming WE, Pollak CP. Sleep disorders in multiple sclerosis. Semin Neurol. 2005;25:64-68
  5. Pokryszko-Dragan A, Bilinska M, Gruszka E, Biel L, Kaminska K, Konieczna K. Sleep disturbances in patients with multiple sclerosis. Neurol Sci. 2013;34:1291-1296
  6. Bamer AM, Johnson KL, Amtmann DA, Kraft GH. Beyond fatigue: Assessing variables associated with sleep problems and use of sleep medications in multiple sclerosis. Clin Epidemiol. 2010;2010:99-106
  7. Kaynak H, Altintaş A, Kaynak D, et al. Fatigue and sleep disturbance in multiple sclerosis. Eur J Neurol. 2006;13:1333-1339
  8. Moreira NC, Damasceno RS, Medeiros CA, et al. Restless leg syndrome, sleep quality and fatigue in multiple sclerosis patients. Braz J Med Biol Res. 2008;41:932-937
  9. Thompson AJ, Banwell BL, Barkhof F, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol. 2018:17;162-173
  10. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983;33:1444-1452
  11. Ağargün MY, Kara H, Anlar Ö. The Validity and reliability of the pittsburgh sleep quality index. Turkish Journal of Psychiatry. 1996;7:107-115
  12. Izci B, Ardic S, Firat H, Sahin A, Altinors M, Karacan I. Reliability and validity studies of the Turkish version of the Epworth Sleepiness Scale. Sleep Breath. 2008;12:161- 168
  13. Gencay-Can A, Can SS. Validation of the Turkish version of the fatigue severity scale in patients with fibromyalgia. Rheumatol Int. 2012;32:27-31
  14. Visser M, Marinus J, Stiggelbout AM, Van Hilten JJ. Assessment of autonomic dysfunction in Parkinson’s disease: the SCOPA-AUT. Mov Disord. 2004;19:1306- 1312
  15. Aydemir Ö. Reliability and Validity of the Turkish version of hospital anxiety and depression scale. Turkish Journal of Psychiatry. 1997;8:280-287
  16. Allen RP, Picchietti DL, Garcia-Borreguero D, et al. Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance. Sleep Med. 2014;15:860- 873
  17. Sakkas GK, Gianna