Journals / Haseki Tıp Bülteni / 2021 / Cilt: 59 - Sayı: 3

The Assessment of Thyroid Hormone Levels in Term and Preterm Infants Diagnosed with Transient Tachypnea of the Newborn: A Cross-Sectional Study

Pages
216–220
DOI
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Late preterms had a lower fT4 level than early termand term groups which was statistically significant but no difference was present between subgroups in TSH levels.Conclusion: Evaluation of thyroid function should be considered especially in preterm babies hospitalized to NICU because of respiratorydistress for an individualized approach if treatment is needed.

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Objective & Hypothesis:Aim: The study aims to evaluate the effect of thyroid hormone levels on the development of transient tachypnea of the newborn (TTN)and neonatal outcomes in preterm and term infants during hospitalization.Methods: Eighty-seven newborns with gestational age ≥34 weeks admitted to neonatal intensive care unit (NICU) between January2016 and December 2019 were enrolled in our retrospective study.
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Key Findings & Data:Maternal features and demographiccharacteristics, thyroid hormones, neonatal outcomes during hospitalization of newborns with TTN were recorded.Results: The mean fT4 level was 1.51±0.33 ng/dL and the median thyroid-stimulating hormone (TSH) level was 3.1 mIU/L.
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Conclusion & Impact:Late preterms had a lower fT4 level than early termand term groups which was statistically significant but no difference was present between subgroups in TSH levels.Conclusion: Evaluation of thyroid function should be considered especially in preterm babies hospitalized to NICU because of respiratorydistress for an individualized approach if treatment is needed.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Özet

Aim: The study aims to evaluate the effect of thyroid hormone levels on the development of transient tachypnea of the newborn (TTN)and neonatal outcomes in preterm and term infants during hospitalization.Methods: Eighty-seven newborns with gestational age ≥34 weeks admitted to neonatal intensive care unit (NICU) between January2016 and December 2019 were enrolled in our retrospective study. The hospital database system and patient files were scannedfor data collection. Infants were divided into three groups (late preterm, early term, and term). Maternal features and demographiccharacteristics, thyroid hormones, neonatal outcomes during hospitalization of newborns with TTN were recorded.Results: The mean fT4 level was 1.51±0.33 ng/dL and the median thyroid-stimulating hormone (TSH) level was 3.1 mIU/L. Among 87infants, 21 were late-preterm, 41 were early-term, and 25 were term infants. There was no difference in the mode of delivery, gender,need, and duration of mechanical ventilation, and non-invasive ventilation or O2 therapy. The mean fT4 level was 1.35±0.29 ng/dL inlate preterms 2.5±2.1 ng/dL in early terms and 1.56±0.25 ng/dL in term infants. Late preterms had a lower fT4 level than early termand term groups which was statistically significant but no difference was present between subgroups in TSH levels.Conclusion: Evaluation of thyroid function should be considered especially in preterm babies hospitalized to NICU because of respiratorydistress for an individualized approach if treatment is needed.

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Cite This Article

ATAOĞLU, E., CEBECİ, B., OĞUZ, D., KURNAZ, D., BÜYÜKKAYHAN, D. (2021). The Assessment of Thyroid Hormone Levels in Term and Preterm Infants Diagnosed with Transient Tachypnea of the Newborn: A Cross-Sectional Study. Haseki Tıp Bülteni, Cilt: 59 - Sayı: 3, 216–220. https://ajindex.com/articles/347932

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References (16)

  1. Bak SY, Shin YH, Jeon JH, et al. Prognostic factors for treatment outcomes in transient tachypnea of the newborn. Pediatr Int 2012;54:875-80
  2. Kasap B, Duman N, Ozer E, Tatli M, Kumral A, Ozkan H. Transient tachypnea of the newborn: predictive factor for prolonged tachypnea. Pediatr Int 2008;50:81-4
  3. Jain L, Dudell GG. Respiratory transition in infants delivered by cesarean section. Semin Perinatol 2006;30:296-304
  4. Hjalmarson O. Epidemiology and classification of acute, neonatal respiratory disorders: a prospective study. Acta Paediatr Scand 1981;70:773-83
  5. Jain L. Alveolar fluid clearance in developing lungs and its role in neonatal transition. Clin Perinatol 1999;26:585-99
  6. Kaltofen T, Haase M, Thome UH, Laube M. Male sex is associated with a reducedalveolar epithelial sodium transport. PLoS One 2015;10:0136178
  7. Baines DL, Folkesson HG, Norlin A, Bingle CD, Yuan HT, Olver RE. The influence of mode of delivery, hormonal status and postnatal O2 environment on epithelial sodium channel (ENaC) expression in perinatal guineapig lung. J Physiol 2000;522:147-57
  8. Bland RD, Nielson DW. Developmental changes in lung epithelial ion transport and liquid movement. Annu Rev Physiol 1992;54:373-94
  9. Barker PM, Olver RE. Clearance of lung liquid during the perinatal period. J Appl Physiol (1985) 2002;93:1542-8
  10. Kessel I, Makhoul IR, Sujov P. Congenital hypothyroidism and nonimmune hydrops fetalis: associated? Pediatrics 1999;103:E9
  11. Hume R, Simpson J, Delahunty C, et al. Human fetal and cord serum thyroid hormones: developmental trends and interrelationships. J Clin Endocrinol Metab 2004;89:4097-103
  12. Geraghty LE, O’Grady M. Neonatal Thyroid Function: Test First, Think Second? Ir Med J 2016;109:460
  13. Behme RM, Mackley AB, Bartoshesky L, Paul DA. Thyroid function in late preterm infants in relation to mode of delivery and respiratory support. J Pediatr Endocrinol Metab 2014;27:425-30
  14. Kayıran SM, Erçin S, Kayıran P, Gursoy T, Gurakan B. Relationship between thyroid hormone levels and transient tachypnea of the newborn in late-preterm, early-term, and term infants. J Matern Fetal Neonatal Med 2019;32:1342-6
  15. Atasay B, Ergun H, Okulu E, Mungan Akın I, Arsan S. The association between cord hormones and transient tachypnea of newborn in late preterm and term neonates who were delivered by cesarean section. J Matern Fetal Neonatal Med 2013;26:877- 80
  16. Biswas S, Buffery J, Enoch H, Bland JM, Walters D, Markiewicz M. A longitud