Journals / Kulak Burun Boğaz İhtisas Dergisi / 2003 / Cilt: 11 - Sayı: 5

Radikal nefrektomiden sekiz yıl sonra renal hücreli karsinomdan tiroit metastazı: Olgu sunumu

Thyroid metastasis from renal cell carcinoma eight years after radical nephrectomy: A case report

Pages
152–156
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although clinically the thyroid gland is a rare site for tumor metastasis, this possibility should be kept in mind in patients with a previous history of renal cell carcinoma.

📌 3 Key Takeaways

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Objective & Hypothesis:A forty-five-year-old female patient presented with thyroid nodules eight years after radical nephrectomy for renal cell carcinoma (T2N0M0, grade 2, clear cell subtype) in the right kidney.
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Key Findings & Data:Immunohistochemical studies demonstrated that the tumor cells were negative for thyroglobulin staining.
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Conclusion & Impact:Although clinically the thyroid gland is a rare site for tumor metastasis, this possibility should be kept in mind in patients with a previous history of renal cell carcinoma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Tiroid neoplazmları · Böbrek neoplazmları · Neoplazm metastazı

Abstract

A forty-five-year-old female patient presented with thyroid nodules eight years after radical nephrectomy for renal cell carcinoma (T2N0M0, grade 2, clear cell subtype) in the right kidney. Ultrasonography of the neck showed multiple hypoechoic macronodules. There was no lymphadenomegaly. During total thyroidectomy following an initial diagnosis of multinoduar goiter, frozen section analysis was made, which showed metastasis from renal cell carcinoma. Immunohistochemical studies demonstrated that the tumor cells were negative for thyroglobulin staining. No recurrences or other metastatic disease were seen during a follow-up period of 12 months. Although clinically the thyroid gland is a rare site for tumor metastasis, this possibility should be kept in mind in patients with a previous history of renal cell carcinoma.

Özet

Sekiz yıl önce sağ renal hücreli karsinom tanısıyla radikal nefrektomi yapılan (T2N0M0 grade 2, berrak hücreli subtip) 45 yaşında kadın hastada tiroitte nodul saptandı. Boyun ultrasonografisinde multipl hipoekoik makronodüler yapı görüldü, lenfadenomagaliye rastlanmadı. Multinodüler guatr düşünülerek yapılan total tiroidektomi sırasında, frozen ile incelenen örnekte renal hücreli karsinom metastazı saptandı, immünhistokimyasal analizde, tiroit tümöründeki berrak hücreler tiroglobulin için boyama göstermedi. Ameliyat sonrasında hastanın 12 aylık izleminde nüks veya başka metastatik hastalığa rastlanmadı. Tiroit bezinde metastaz çok nadir olsa da, renal hücreli karsinom öyküsü olan hastalarda tiroide metastaz olabileceği göz önünde bulundurulmalıdır.

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Cite This Article

UZEL, C., COŞKUN, H., TERZİOĞLU, T., ARAS, N. (2003). Radikal nefrektomiden sekiz yıl sonra renal hücreli karsinomdan tiroit metastazı: Olgu sunumu. Kulak Burun Boğaz İhtisas Dergisi, Cilt: 11 - Sayı: 5, 152–156. https://ajindex.com/articles/343160

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References (1)

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