Journals / Kulak Burun Boğaz İhtisas Dergisi / 2003 / Cilt: 10 - Sayı: 5

An evaluation of surgical techniques and oncologic results in early glottic cancers

Erken evreli glottik kanserlerde cerrahi tedavi seçimi ve onkolojik sonuçlar

Pages
194–198
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Involvement of the anterior commissure, and the extent of invasion to the subglottis, supraglottis, and the laryngeal ventricle seem to play a major role in selecting the most appropriate surgical technique in early glottic cancer.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: We evaluated the surgical techniques employed and survival rates in patients who were treat-ed for early glottic cancer.
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Key Findings & Data:Patients and Methods: The study included 29 patients (28 males, 1 female; mean age 59 years; range 47 to 73 years) who underwent surgery for early glottic cancer.
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Conclusion & Impact:Conclusion: Involvement of the anterior commissure, and the extent of invasion to the subglottis, supraglottis, and the laryngeal ventricle seem to play a major role in selecting the most appropriate surgical technique in early glottic cancer.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Sağkalım oranı · Glottis · Kulak-burun-boğaz cerrahi işlemleri

Abstract

Objectives: We evaluated the surgical techniques employed and survival rates in patients who were treat-ed for early glottic cancer. Patients and Methods: The study included 29 patients (28 males, 1 female; mean age 59 years; range 47 to 73 years) who underwent surgery for early glottic cancer. Surgical techniques were employed in view of factors such as involvement of the anterior commissure, the extent of sub-or supraglottic invasion, and cord mobility. Two- and five-year survival rates were calculated. TNM classification was made according to the 1992 AJCC staging system. Results: Preoperative tumor stages were TisN0 (n=2,7%), TiN0 (n=20, 69%), and T2N0 (n=7, 24%). Surgical tech-niques included laryngofissure and cordectomy (n=9,31 %), frontolateral laryngectomy (n=18, 62%), and vertical hemi-laryngectomy (n=2, 7%). Positive surgical margins were reported postoperatively in 10 patients, eight of whom remained tumor-free with (n=4) or without (n=4) radiation therapy during the follow-up period, while two patients underwent total laryngectomy because of local recurrences. Three patients died due to causes other than the primary disease. Two- and five-year survival rates were 88.8% and 80%, respectively. Conclusion: Involvement of the anterior commissure, and the extent of invasion to the subglottis, supraglottis, and the laryngeal ventricle seem to play a major role in selecting the most appropriate surgical technique in early glottic cancer.

Özet

Amaç: Erken evreli glottik kanser tanısı ile cerrahi tedavi uygulanan olgularda seçilen cerrahi yöntem ve sağkalım oranları değerlendirildi. Hastalar ve Yöntemler: Çalışmaya erken evreli glottik kanseri nedeniyle cerrahi tedavi gören 29 hasta (28 erkek, 1 kadın; ort. yaş 59; dağılım 47-73) alındı. Ön komissür tutulumu, sub- veya supraglottik yayılım derecesi ve kord mobilitesi gibi faktörler göz önüne alınarak uygulanan cerrahi yöntemler ve sağkalım oranları belirlendi. Tümörlerin TNM sınıflandırması American Joint Committee on Cancer (AJCC) 1992 ölçütlerine göre yapıldı. Bulgular: Tümör evreleri iki olguda (%7) TİSN0, 20 olguda (%69) T1N0, yedi olguda (%24) T2N0 bulundu. Dokuz olguda (%31) larengofissür+kordektomi, 18 olguda (%62) frontolateral larenjektomi, iki olguda (%7) vertikal hemilarenjektomi yapıldı. On olgunun ameliyat sonrası histopatolojik incelemelerinde cerrahi sınır po-zitifliği belirlendi. Bunların dördü radyoterapi sonrasın-da, diğer dördü rutin kontrollerinde sorunsuz olarak izlendi; diğer iki olguda ise nüks nedeniyle total larenjektomi yapıldı. Yalnızca üç olgu hastalık dışı nedenlerle kaybedildi. İki yıllık sağkalım oranı %88.8, beş yıllık sağkalım oranı %80 bulundu. Sonuç: Erken evreli glottik kanserli hastalarda, ön komissür tutulumu, subglottise, supraglöttise ve ventriküle yayılım derecesi uygulanacak cerrahi yöntemin seçiminde büyük önem taşımaktadır.

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Cite This Article

GÜRBÜZ, M. K., ÖZÜDOĞRU, E. N., ÇAKLI, H., CİNGİ, E., KEÇİK, M. C., CİNGİ, C. (2003). An evaluation of surgical techniques and oncologic results in early glottic cancers. Kulak Burun Boğaz İhtisas Dergisi, Cilt: 10 - Sayı: 5, 194–198. https://ajindex.com/articles/342931

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