Journals / Kulak Burun Boğaz İhtisas Dergisi / 1999 / Cilt: 6 - Sayı: 1

The effect of tonsillectomy on serum immunoglobulin levels

Tonsillektominin serum immünglobulinleri üzerine etkisi

Pages
43–45
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Tonsillectomy-induced decreases in immunoglobulin levels especially in the late period should be considered in tonsillectomy indications.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: To determine tonsillectomy-induced changes in serum immunoglobulin levels.
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Key Findings & Data:Design and Methods: Serum IgG, IgA, IgM, and IgE levels were evaluated in 40 children (age range 5-12 years) who underwent tonsillectomy.
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Conclusion & Impact:Conclusion: Tonsillectomy-induced decreases in immunoglobulin levels especially in the late period should be considered in tonsillectomy indications.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:IgG · Tonsillit · IgM

Abstract

Objectives: To determine tonsillectomy-induced changes in serum immunoglobulin levels. Design and Methods: Serum IgG, IgA, IgM, and IgE levels were evaluated in 40 children (age range 5-12 years) who underwent tonsillectomy. Measurements were made before, one month after, and 12 months after the operation. For comparison, serum samples were obtained from 30 healthy children. Results: Initially, IgG, IgA, and IgE levels in patients with chronic tonsillitis were significantly higher than those of the control group (p<0.01, p<0.05, and p<0.05, respectively). After tonsillectomy, serum levels of IgG, IgA, IgM, and IgE significantly decreased, especially in the late period (p<0.01, p<0.01, p<0.01, and p<0.01, respectively). Conclusion: Tonsillectomy-induced decreases in immunoglobulin levels especially in the late period should be considered in tonsillectomy indications.

Özet

Amaç: Tonsillektominin serum immunglobulin düzeylerine etkisi olup olmadığını araştırmak. Çalışma Planı ve Yöntemler: Tonsillektomi uygulanan 5-12 yaşları arasında 40 hastada ameliyat öncesi, erken (tonsillektomiden bir ay sonra) ve geç (tonsillektomiden 12 ay sonra) dönemdeki serum IgG, IgA, IgM ve IgE düzeyleri ölçüldü. Aynı yaş grubundan 30 sağlıklı çocuktan serum örnekleri alınarak immunglobulin düzeylerine bakıldı. Bulgular: Kronik tonsillitli hastalarda serum IgG, IgA ve IgE düzeylerindeki yükseklik kontrol grubuna göre anlamlı bulundu (sırasıyla p<0.01, p<0.05 ve p<0.05). Tonsillektomi sonrası, özellikle geç dönemde IgG, IgA, IgM ve IgE'de anlamlı düşme saptandı (sırasıyla p<0.01, p<0.01, p<0.01 ve p<0.01). Sonuç: Tonsillektominin özellikle geç dönemde immunglobulin düzeylerinde anlamlı düşmeye neden olması endikasyonlarında göz önüne alınmalıdır.

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Cite This Article

TEKİN, M., OSMA, Ü., ÜSTEL, M., MERİÇ, F., OKTAY, F., TURGUT, C., TOPÇU, İ. (1999). The effect of tonsillectomy on serum immunoglobulin levels. Kulak Burun Boğaz İhtisas Dergisi, Cilt: 6 - Sayı: 1, 43–45. https://ajindex.com/articles/342907