Journals / Yüzüncü Yıl Üniversitesi Veteriner Fakültesi Dergisi / 2004 / Cilt: 15 - Sayı: 1

Tavşanlarda yara iyileşmesi üzerinde tissupor yara pedi'nin etkinliği

Efficacy of tissupor wound pad on wound healing in rabbits

Pages
37–40
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, ur think that this method could be quite advantageous for the treatment of wounds because it either shortens the duration of wound healing, or decreases the total number of wound dressing changes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The tifect of Tissupor (TP) wound pad on wound heeding was compared to thai of a commonly used 10 % povidon iodine antiseptic solution.
📊
Key Findings & Data:Two full-thickness skin defects, 3 cm in diameter, were created bilaterally on the costal regions of I0 rabbits.
💡
Conclusion & Impact:As a result, ur think that this method could be quite advantageous for the treatment of wounds because it either shortens the duration of wound healing, or decreases the total number of wound dressing changes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:tavşan · histopatoloji · doku iyileşmesi

Abstract

The tifect of Tissupor (TP) wound pad on wound heeding was compared to thai of a commonly used 10 % povidon iodine antiseptic solution. Two full-thickness skin defects, 3 cm in diameter, were created bilaterally on the costal regions of I0 rabbits. While the defect on the left side was treated with TP with changes every 3 days, the one on the right side was treated with 10 % povidon iodine solution (control). The dressings were changed in every 2 days until epithelializatiou. Wound surfaces were niacroscopically examined during the postoperative period. Biopsy specimens collected on the $3^{rd},6^{th},9^{th}and12^{th}$ days post-incision were evaluated for histopathologieal changes. Specimens were scored for fibroblast proliferation, edema, inflammatory cells, and vascular proliferation. The number of days needed for epithelialization was significantly (p<0.001) reduced in the TP group (8.70 ± 0.47 dnvs) compared with control group (13.50 i 0.56 days). On days 6, 9, and 12, there ira.y significant increase in granulation tissue in TP applied tissues composed of capillary vessels and proliferation of fibroblast. In summary, TP application to full-iliiekness skin defects in rabbits accelerated wound healing. As a result, ur think that this method could be quite advantageous for the treatment of wounds because it either shortens the duration of wound healing, or decreases the total number of wound dressing changes.

Özet

Tissupor (TP) yara pedinin yara iyileşmesi tilerine etkisi yaygın olarak kullanılan % 10 povidon iodine antiseptik solüsyonu ile karşılaştırıldı. 10 tavşanın kast al bölgesinde j cm çapında iam katlı deri yarası bilateral olarak oluşturuldu. Sol tarafta oluşturulan vara, 3 günde bir pansumanı değiştirilen TP ile, sağ taraftaki yara ise % 10 povidon iodiııe solüsyonu (kontrol) ile tedavi edildi. Pansumanlar, epitelizasyon oluşana kadar 2 günde bir değiştirildi. Yara yüzeyleri, postoperatif dönemde makroskobik olarak incelendi. Ensizyon sonrası 3, 6, 9 ve 12. günlerde alınan biyopsi örnekleri, histopatolojik değişiklikleri değerlendirmek için incelendi. Alman örnekler; fibroblast proliferasyonu, ödem, yangısal hücreler ve damarsal proliferasyon açısından skorlandı. Tl' grubunda epitelizasyon oluşması için gerekli süre (S. 70 ± 0.47 gün) kontrol grubu ile karşılaştırıldığında (13.50 ± 0.56 gün) belirgin derecede (p<0.00l) kısa idi. 6, 9 ve 12. günlerde TP uygulanan dokularda kapıl/er damarlar ve fibroblast proliferasyotıundan oluşan granula.syon dokusunda belirgin bir artış gözlendi. Özetle, tavşanlarda lam katlı deri yaralarına TP uygulaması yara iyileşmesini hızlandırdı. Sonuç olarak; hu metodun hem yara iyileşme süresini hem de toplanı pansuman değişimi sayısını azalttığı için, yara tedavisinde oldukça avantajlı olduğunu düşünmekteyiz.

🔖

Cite This Article

SELÇUKBİRİCİK, H., ŞINDAK, N., HAYAT, A., ERASLAN, H., GANİDAĞLI, S., TURSUN, G. (2004). Tavşanlarda yara iyileşmesi üzerinde tissupor yara pedi'nin etkinliği. Yüzüncü Yıl Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 15 - Sayı: 1, 37–40. https://ajindex.com/articles/339889

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Bertone AL (1998): Second Intention Healing. Vet. Clin. North Am. Equine Pract. 14. (5): 539-550
  2. Cochrane CA (1997): Models in vivo of Wound Healirm in the Horse and the Role of Growt Factors. Vet. Dermatol. S, (4): 259-272
  3. Dyson M (1997): Advances in Wound Healing Physiology: The Comparative Prospective. Vet. Dermatol. S, (4): 227-233
  4. Ferz t PB, Martin GS, Jacobs KA (1983): Treatment of Exubarent Granulation Tissue in the Horse: Evaluation of Four Methods. Vet. Surg. 13, 137-140
  5. Folkman M, Shing Y (1992): Angiogenesis. J. Biol. Chem. 267, (16): 10931-10934
  6. Gillette RL, Swaim SF, Sartin EA, Bradley DM, Coolman SL (2001): Effects of a Bioactive Glass on Healing of Closed Skin Wounds in Dogs. Am. J. Vet. Res. 62, (7): 1149-1153 7. Jean KY, Gaughan E, Jean G, Frank R (1995): Evaluation of a Porous Bovine Collagen Membrane Bandage for Management of Wounds in Horses. Am. J. Vet. Res. 56, (12): 1663-1667
  7. Karamuk E, Biilia M, BischoH'B, Ferrario R, Wagner B, Moser R, Wanner M, Mayer J (2001): Development of a Textile Wound Dressing Based on Embroidery Technology. Eurropean Cells and Materials. 1 (Suppl l):3-4
  8. Kılıç S, Ti nm r kan N, Ünsaîdı S, Gün ay C, İstek Ö, Yılmaz B (2002): Comparison of the Effects of Some Wound Healing Materials on Full Thickness Skin Wounds in Rabbits. Turk. J. Vet. Anim. Sci. 26, (2): 263-272
  9. KnottenbeK DC (1997): Equine Wound Management: Are There Significant Differences in Healing at Different Sites on the Body. Vet. Dermatol, 8: (4): 273-290
  10. Kumar, V, Abbas, AK, Fausto, N (2004).Pathologic Basis of Disease. $7^{th}$ edn, Elsevier Saunders China
  11. Sahili M (2001): The Effects of Different; Suture Techniques on Wound Healing in Abdominal Wail: Closure. Turk. J. Med. Sci. 31, (5): 391-394
  12. Sarin S, Cheatle TR, Smith PD, Scurr JH (1991): Disease Mechanisms in Venoulceration. Brit,J. Hosp. Med. 45. (5): 303-305
  13. Shami SK, Shields DA, Scurr JH, Smith PD (1992): Leg Ulceration in Venous Disease. Postgr. Med. J. 68, (804): 779-785
  14. Steven S (1997): Advances in Wound Healing in Small Animal Practice: Current Status and Lines of Development. Vet. Dermatol. S, (4): 249-257
  15. Taş A, Atasoy N, Özbek H, Aslan L, Yüksel H, Ceylan E, Dağoğlu G (2003): The Effects of Sildenafil Citrate (Viagra) in the Early Phase Mealing Process in Open Wounds in Dogs. Acta Vet. Brno, 72. (2): 273-277
  16. Wanner M, Karamuk E, Billia M. Bischoff B, Ferrario R, Wagner B, Moser R., Mayer J: Preliminary Results o