Journals / Yeni Tıp Dergisi / 2011 / Cilt: 28 - Sayı: 4

Relationship between metabolic syndrome and inflamation in hemodialysis Patients

Hemodiyaliz hastalarında metabolik sendrom’un inflamasyonla ilişkisi

Pages
231–234
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Hemodialysis patients with Metabolic syndrome should also be assessed for inflammation.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, we aimed to investigate the relationship between inflammation and metabolic syndrome as defined by the International Diabetes Federation (IDF) diagnostic criteria in hemodialysis patients.
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Key Findings & Data:Patients’ age, sex, weight, waist circumference, arterial blood pressure, fasting blood glucose, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, C-reactive protein, albumin, uric acid and fibrinogen levels were recorded.
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Conclusion & Impact:Conclusion: Hemodialysis patients with Metabolic syndrome should also be assessed for inflammation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to investigate the relationship between inflammation and metabolic syndrome as defined by the International Diabetes Federation (IDF) diagnostic criteria in hemodialysis patients. Material and Methods: Two hundred and seventy four patients treated with hemodialysis were included in the study. Patients&#8217; age, sex, weight, waist circumference, arterial blood pressure, fasting blood glucose, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, C-reactive protein, albumin, uric acid and fibrinogen levels were recorded. Results: Eighty two patients diagnosed with metabolic syndrome and 192 hemodialysis patients without metabolic syndrome were identified. In the Metabolic syndrome group mean decrease in serum albumin and mean increase in C-reactive protein and fibrinogen was significantly different from the other group (p<0.05, p<0.001, p<0.05, respectively). When gender, diabetes mellitus, and hypertension status was evaluated, there was a significant difference in terms of the proportion of women and diabetes mellitus (p<0,001), but the presence of hypertension and mean serum uric acide levels did not differ significantly. Conclusion: Hemodialysis patients with Metabolic syndrome should also be assessed for inflammation.

Özet

Amaç: Bu çalışmada hemodiyaliz hastalarında Uluslararası Diyabet Federasyonu (IDF) tarafından tanımlanan metabolik sendrom tanı kriterlerine göre metabolik sendrom tanısı olan ve olmayan hastalarda inflamasyon arasındaki ilişkiyi araştırmayı amaçladık. Materyal ve Metot: Bu çalışmaya hemodiyaliz tedavisi gören toplam 274 hasta alındı. Metabolik sendrom tanısı alan ve almayan hastalarda yaş, cinsiyet, ağırlık, bel çevresi, arteriyel kan basınçları, açlık kan şekeri, total kolesterol, LDL-kolesterol, HDL-kolesterol, trigliserid, Creaktif protein (CRP), albümin, ürik asit ve fibrinojen düzeyleri araştırıldı. Bulgular: Metabolik sendrom tanısı konulan 82 hasta ve metabolik sendrom tanısı konulmayan 192 hemodiyaliz hastası tespit edildi. Metabolik sendrom tanısı konulan gruptaki ortalama serum albümin düşüklüğü, CRP yüksekliği, fibrinojen yüksekliği metabolik sendrom tanısı konulmayan gruba göre istatistiksel olarak anlamlı bulundu (p<0,05, p<0,001, p<0,05). Cinsiyet, diyabetes mellitus ve hipertansiyon durumu açısından değerlendirildiğinde metabolik sendrom tespit edilen grupta kadın oranı ve diyabetes mellitus oranı daha fazla bulunurken (p<0,001), hipertansiyon varlığı ve ortalama serum ürik asit seviyesi açısından anlamlı düzeyde fark bulunmadı. Sonuç: Metabolik sendrom tespit edilen hemodiyaliz hastalarının inflamasyon markırları açısından da değerlendirilmesinin uygun olacağını düşünmekteyiz.

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Cite This Article

BORAZAN, A., EMİR, İ., UÇAR, E., TEKİŞ, İ. Z. (2011). Relationship between metabolic syndrome and inflamation in hemodialysis Patients. Yeni Tıp Dergisi, Cilt: 28 - Sayı: 4, 231–234. https://ajindex.com/articles/338432

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