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Journals / Yeni Tıp Dergisi / 2011 / Cilt: 28 - Sayı: 1

Obez kadınlarda serum ürik asit düzeyleri

Serum uric acid levels in obese women

Ayşe ÇARLIOĞLU
Feridun KARAKURT
Senen MARAL
Benen KASAPOĞLU
Tahir DARCIN
Pages
34–37
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, higher uric acid levels in obese patients indicate on increased cardiovascular disease risk and oxidative stress.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hyperuricemia is known as an independent risk factor for renal dysfunction in the normal population and in patients with hypertension or diabetes.
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Key Findings & Data:A prospective study was performed in 644 female, with a mean age of 51±9.7 years.
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Conclusion & Impact:In conclusion, higher uric acid levels in obese patients indicate on increased cardiovascular disease risk and oxidative stress.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hyperuricemia is known as an independent risk factor for renal dysfunction in the normal population and in patients with hypertension or diabetes. The purpose of this study is to examine the contribution of obesity to uric acid levels in patents. A prospective study was performed in 644 female, with a mean age of 51±9.7 years. The patients were divided into three groups according to their body mass index levels as; obese (BMI:over 30) (n:387), over-weight group (BMI:25-29.9) (n: 257) and normal weight control group (BMI:18.5-24.9) (n:196). Uric acid and creatinine levels were significantly higher in obese than control and over-weight groups. In conclusion, higher uric acid levels in obese patients indicate on increased cardiovascular disease risk and oxidative stress. This particular finding is also important in development of chronic renal failure in obese individuals which in turn may increase morbidity and mortality.

Özet

Normal populasyonda ve hipertansiyonu ya da diyabeti olanlarda hiperürisemi renal disfonksiyon için bağımsız bir risk faktörü olarak bilinir. Bu çalışmanın amacı has-talarda obezitenin ürik asit seviyeleri üzerine etkilerini araştırmaktır. Ortalama yaşı 51±9,7 yıl olan 644 kadın üzerinde prospektif bir çalışma gerçekleştirildi. Hastalar Beden kitle indekslerine (BKİ) göre 3 gruba ayrıldı; obez grup (BKİ:>30) (n:387), fazla kilolu grup (BKİ:25-29.9) (n: 257) ve normal kilolu kontrol grubu (BKİ:18,5-24,9) (n:196). Obez grupta ürik asit ve kreatinin değerleri kontrol ve fazla kilolu gruptan anlamlı olarak daha yüksekti. Obez hastalardakiartmış ürik asit seviyeleri artmış kardiyovasküler hastalık riski ve oksidatif stresin bir göstergesidir. Bu bulgu obez hastalarda morbidite ve mortaliteyi arttırabilecek olan kronik böbrek yetmezliği gelişimi için de önemli olabilir.

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Cite This Article

ÇARLIOĞLU, A., KARAKURT, F., MARAL, S., KASAPOĞLU, B., DARCIN, T. (2011). Obez kadınlarda serum ürik asit düzeyleri. Yeni Tıp Dergisi, Cilt: 28 - Sayı: 1, 34–37. https://ajindex.com/articles/338308

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