Journals / Yeni Tıp Dergisi / 2013 / Cilt: 30 - Sayı: 2

Deneysel olarak indüklenmiş sıçan endometriyozis modelinde implantasyon kusurunun histolojik değerlendirilmesi

Histological evaluation of implantation deficit in experimentally induced e ndometriosis model of rats

Pages
124–130
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Yet, morpho- metry may pioneer novel ultrasonographic modules in future.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Experimental animal models are impor- tant in understanding human endometriotic disease.
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Key Findings & Data:Material and Method: Decidua reaction were detected in surgical endometriosis induction group (n=20), sham operated (n=10) and non-operated control (n=10) groups and studied with routine light microscopic, electron microscopic and immunohistochemical techniques as well as histologic, morphometric and biochemical analysis.
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Conclusion & Impact:Yet, morpho- metry may pioneer novel ultrasonographic modules in future.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Experimental animal models are impor- tant in understanding human endometriotic disease. Aims: This study aims to describe factors influencing the implantation deficit in experimental endometriosis. Material and Method: Decidua reaction were detected in surgical endometriosis induction group (n=20), sham operated (n=10) and non-operated control (n=10) groups and studied with routine light microscopic, electron microscopic and immunohistochemical techniques as well as histologic, morphometric and biochemical analysis. Results: Decidualisation and pinopode expression of eutopic endometrium in surgically induced endometriosis relatively decreased and adequate endometrial morpho- logy may not always display normal endometrial receptivity. Although mitotic figures were described, study groups revealed statistically significant thickness differences in morphometry. Conclusions: Uterine receptivity defects are regulated differently while other alternative mechanisms effecting endometrial receptivity sustained. In addition, unsignifi- cant differences of immunohistochemical expressions are non-descriptive due to the antibodies used for uterine receptivity in experimental endometriosis. Yet, morpho- metry may pioneer novel ultrasonographic modules in future.

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Cite This Article

YILMAZ, Ö. D., ULUKUŞ, M., SÖZMEN, E., ATEŞ, U., ERTEM, M. (2013). Deneysel olarak indüklenmiş sıçan endometriyozis modelinde implantasyon kusurunun histolojik değerlendirilmesi. Yeni Tıp Dergisi, Cilt: 30 - Sayı: 2, 124–130. https://ajindex.com/articles/338206

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