Journals / Yeni Tıp Dergisi / 2013 / Cilt: 30 - Sayı: 3

(Paklitakselin neden olduğu subungual kanama: Bir olgu)

Paclitaxel induced subungual hemorrhage: A case report

Pages
202–203
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The subungual haemorrhages could be developed following to paclitaxel usage.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 46-year-old woman with infiltrating ductal carcinoma of the breast cancer developed nail toxicity while she was being treated with paclitaxel for twelve weeks.
📊
Key Findings & Data:Paclitaxel is a chemotherapeutic agent of the taxane family.
💡
Conclusion & Impact:The subungual haemorrhages could be developed following to paclitaxel usage.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 46-year-old woman with infiltrating ductal carcinoma of the breast cancer developed nail toxicity while she was being treated with paclitaxel for twelve weeks. Paclitaxel is a chemotherapeutic agent of the taxane family. Various cutaneous side effects, including nail changes, have been associated with taxane chemothe- rapeutic agents. The subungual haemorrhages could be developed following to paclitaxel usage.

Özet

İnfiltratif duktal karsinomu tanısı olan 46 yaşındaki bir kadın hastanın paklitaksel ile tedavisinin on ikinci hafta- sında tırnak toksisitesi gelişti. Paklitaksel taksan ailesin- den bir kemoterapötik ajandır. Taksan grubu kemotera- pötik ajanların tırnak değişiklikleri de dahil olmak üzere çeşitli kutanöz yan etkileri bildirilmiştir. Subungual kana- malar da paklitaksel kullanımı sonrasında gelişebilir.

🔖

Cite This Article

CEMİL, B. Ç., EMİROĞLU, N., İMAMOĞLU, G. İ., CENGİZ, F. P., ŞAŞMAZ, R. (2013). (Paklitakselin neden olduğu subungual kanama: Bir olgu). Yeni Tıp Dergisi, Cilt: 30 - Sayı: 3, 202–203. https://ajindex.com/articles/338195

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Uyttendaele H, Geyer A, Scher RK. Drugs and nails. J Eur Acad Dermatol Venereol 2004;18:124-5
  2. Crown J, O'Leary M. The taxanes: an update. Lancet 2000; 355:1176-8
  3. Minisini AM, Tosti A, Sobrero AF, Mansutti M, Piraccini BM, Sacco C, et al. Taxane-induced nail changes: incidence, clinical presentation and outcome. Ann Oncol 2003;14:333-7
  4. Rowinsky EK, Tolcher AW. Antimicrotubule agents. In De Vita VT Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology, 6th edition. Philadelphia, PA: Lippincott Williams & Wilkins 2001; 431–47
  5. Ghetti E, Piraccini BM, Tosti A. Onycholysis and subungual haemorrhages secondary to systemic chemotherapy (paclitaxel). J Eur Acad Dermatol Venereol 2003;17:459-60
  6. Hussain S, Anderson DN, Salvatti ME, Adamson B, McManus M, Braverman AS. Onycholysis as a complication of systemic chemotherapy: report of five cases associated with prolonged weekly paclitaxel therapy and review of the literature. Cancer 2000;88:2367-71
  7. Daniel CR 3rd, Scher RK. Nail changes secondary to systemic drugs or ingestants. J Am Acad Dermatol 1984;10:250-8
  8. Young PC, Montemarano AD, Lee N, Sau P, Weiss RB, James WD. Hypersensitivity to paclitaxel manifested as a bullous fixed drug eruption. J Am Acad Dermatol 1996;34:313-4
  9. Yeo W, Leung SF, Johnson PJ. Radiation-recall dermatitis with docetaxel: establishment of a requisite radiation threshold. Eur J Cancer 1997;33:698-9
  10. Weinberg JM, Egan CL, Tangoren IA, Li LJ, Laughinghouse KA, Guzzo CA. Generalized pustular dermatosis following paclitaxel therapy. Int J Dermatol 1997;36:559-60
  11. Almagro M, Pozo JD, Garcia J, Vasquez A, Fonseca E. Nail alterations secondary to pactitaxel [corrected] therapy. Eur J Dermatol 2000;10:146-7
  12. Correia O, Azevedo C, Pinto Ferreira E, Braga Cruz F, PolóniaNail changes secondary to docetaxel (Taxotere). Dermatology 1999;198: 288-90
  13. Piccart MJ, Klijn J, Paridaens R, Nooij M, Mauriac L, Coleman R,al. Corticosteroids significantly delay the onset of docetaxel-induced fluid retention: final results of a randomized study of the European Organization for Research and Treatment of Cancer Investigational Drug Branch for Breast Cancer. J Clin Oncol 1997;15:3149-55
  14. Lüftner D, Flath B, Akrivakis C, Schweigert M, PrinzMergenthaler HG, et al. Dose-intensified weekly paclitaxel induces multiple nail disorders. Ann Oncol 1998;9:1139-40
  15. Flory SM, Solimando DA Jr, Webster GF, Dunton CJ, Neufeld JM, Haffey MB. Onycholysis a