Journals / Yeni Üroloji Dergisi / 2008 / Cilt: 4 - Sayı: 2

Testicular torsion and apopitosis

Testis torsiyonu ve apopitozis

Pages
61–68
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Following the reperfusion, free radicals which lead to germ cell apopitosis occur in the tissue.Germ cell apopitosis also increases tissue injury.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Testicular torsion is a urological emergency that causes testicular ischemia in men.
📊
Key Findings & Data:Torsion decreases Ipbilateral testicular perfusion.
💡
Conclusion & Impact:Following the reperfusion, free radicals which lead to germ cell apopitosis occur in the tissue.Germ cell apopitosis also increases tissue injury.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Reperfüzyon · Germ hücreleri · İskemi

Abstract

Testicular torsion is a urological emergency that causes testicular ischemia in men. Torsion decreases Ipbilateral testicular perfusion. Following the reperfusion, free radicals which lead to germ cell apopitosis occur in the tissue.Germ cell apopitosis also increases tissue injury.

Özet

ÖZET: Testis torsiyonu, erkeklerde testisin iskemik kalmasına neden olabilen ürolojik bir acil durumdur. Torsiyon etkilenen testiste perfüzyonun azalmasına yol açar. Reperfüzyonun ardından dokuda germ hücre apopitozisine neden olacak rbest oksijen radikalleri oluşur. Germ hücre apopitozisi ise doku yıkımının daha da artmasına neden olmaktadır.

🔖

Cite This Article

AKGÜL, T., SÜRER, H., AYYILDIZ, A. (2008). Testicular torsion and apopitosis. Yeni Üroloji Dergisi, Cilt: 4 - Sayı: 2, 61–68. https://ajindex.com/articles/337454

References (23)

  1. Burger SW:Acute scrotal pain. Emerg Med Clin North Am, 1998
  2. Anderson JB, Williamson CAN:The fate of the human testis following unilateral torsion of the spermatic cord. Br J Urol, 1996
  3. Workman SJ, Kogan BA: Old and new aspects of testicular torsion. Semin Ural, 1998
  4. Akgur FM, Kiline K, Aktug T, Olguner M: The effect of allopurinol pretreatment before testicular torsion. J Urol, 1994
  5. Kramp T: Testis after torsion. Br J Surg, 1978
  6. Sastre J, Pallardo FV, Vina J: Glutathione, oxidative stress, and aging. Age, 1996
  7. Samanta L,Chaing GB:Comparison of hexachlorocyclohexane-induced oxidative stress in the testis of immature and adult rats. Com Biochem Physiol, 1998
  8. Lucesoli F, Fraga CG: Oxidative stress in testes of rats subjected to chronic ion intoxication and _-tocopherol supplementation. Toxicology, 1999
  9. Bosman FT, Visser BC,Oeveren JV: Apoptosis:pathophysiology of programmed cell death. Path Res Pract, 1996
  10. Green DR: Apoptotic pathways: the road to ruin. Cell, 1998
  11. Hengartner MO: The biochemistry of apoptosis. Nature, 2000
  12. Adams JM, Cory S: The Bcl-2 protein family: arbiters of cell survival. Science, 1998
  13. Wyllic AH: Glucocorticoid-induced thymocytc apoptosis is associated with endogenous riuclease activation. Nature, 1980
  14. Nagata S: Apoptosis by death factor. Cell, 1997
  15. Krammer PH: CD95's deadly mission in the immune system. Nature, 1998
  16. Matsui Y: Regulation of germ cell death in mammalian gonads. APMIS, 1998
  17. Van der Vusse GJ, Reneman RS: Pharmacological intervention in acute myocardial ischemia and reperfusion. Trends Physiol Sci, 1985
  18. Weins SW, Lucchesi BR: Free radicals and işchemic tissue injury. Trends Physiol Sci, 1990
  19. Nathan CE Root RK: Hydrogen peroxide release from mouse peritoneal macrophages. J Exp Med, 1977
  20. 1662, 20.Fliss H, Gattinger D: Apoptosis in ischemic and reperfused rat myocardium. Circ Res, 1996
  21. 956, 21.Sasaki H, Matsuno T, Tanaka N, et al: Activation of apoptosis during the reperfusion phase after rat liver ischemia. Transplant Proc, 1996
  22. Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science, 1995
  23. Johnson TM, Yu XZ, Ferans VJ, et al: Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc Natl