SavedAdd your journal

Journals / Zeynep Kamil Tıp Bülteni / 2003 / Cilt: 34 - Sayı: 4

Estrogen and progesteron receptor expression in cellular leiomyomas and leiomyosarcomas

Selüler leiomyon ve leiomyosarkomlarda östrojen ve progesteron reseptör ekspresyonu

Gözde KIR
Handan ÇETİNER
Ayşe GÜRBÜZ
Sadiye EREN
Pages
19–21
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Out-of 17 CMs 13 showed PR overexpression.(LMS PR overexpressionxCMPR overexpression,p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective:To evaluate estrogen(ER) and progesteron(PR) receptor expression in cellular leiomyomas and leiomyosarcomas Materials and Methods: The study includes 17 cases of cellular leiomyoma(CM) and 7 cases of leiomyosarcoma(LMS) which were diagnosed in Pathology Department of Zeynep Kamil Hoşpital between 1997 and 2003 years.
📊
Key Findings & Data:One paraffin-embedded tümör tissue per each case were analyzed immunohistochemically for ER and PR ,receptors.
💡
Conclusion & Impact:Out-of 17 CMs 13 showed PR overexpression.(LMS PR overexpressionxCMPR overexpression,p
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Leyomiyom · Leyomiyosarkom · Reseptörler

Abstract

Objective:To evaluate estrogen(ER) and progesteron(PR) receptor expression in cellular leiomyomas and leiomyosarcomas Materials and Methods: The study includes 17 cases of cellular leiomyoma(CM) and 7 cases of leiomyosarcoma(LMS) which were diagnosed in Pathology Department of Zeynep Kamil Hoşpital between 1997 and 2003 years. One paraffin-embedded tümör tissue per each case were analyzed immunohistochemically for ER and PR ,receptors. Results: None of LMSs showed 'overexpression' for PR. Out-of 17 CMs 13 showed PR overexpression.(LMS PR overexpressionxCMPR overexpression,p

Özet

Amaç: Selüler leiomyom ve leimyo sarkomların Ostrojen ve progesteron reseptör ekspresyonlarını değerlendirmek. Materyal ve Method: 1997-2003 yıUarı arasında Zeynep Kamil Hastanesi Patoloji Bölümünde tanı almış 17 selüler leimyom ve 7 leiomyosarkom olgusu çalışma kapsamına alındı. Tümörleri temsil eden birer parafin blokda immunhisto kimyasal yöntemle östrojen ve progesteron reseptör boyanması incelendi. Bulgular: Leiomy'Osarkomların hiçbirinde progesteron resptörü için "overexpression"'(OE) izlenmedi. Onyedi adet selüler leibmyomun 13 ünde OE saptandı (LMS PR-OE x SM PR-OE, p

🔖

Cite This Article

KIR, G., ÇETİNER, H., GÜRBÜZ, A., EREN, S. (2003). Estrogen and progesteron receptor expression in cellular leiomyomas and leiomyosarcomas. Zeynep Kamil Tıp Bülteni, Cilt: 34 - Sayı: 4, 19–21. https://ajindex.com/articles/335672

References (1)

  1. Zaloudek CJ, Hendrickson MR. Mesenchymal tumors of the uterus. In: Kurman RJ, ed. Blaustein's Pathology of Female Genital Tract. 5th ed. New York: Springer-Verlag 2 002: 561-616 2. Buttrom VC, Reiter RC. Uterine leiomyomata: etiology symptomatology and management. Fertil Steril 1981, 36:433-5 3. Kamaguchi K, Fujii S, Konishi I, Nanbu Y, Nonogaki H, Mori T. Mitotik activity in uterine leimyoma during the menstrual cycle. Am J Obstet Gynecoll989; 160: 637-41 4. Kawaguchi K, Fujii S, Konishi I, et al Immunohistochemical analysis of oestrogen receptors, progesterone receptors and Ki-67 in leiomyoma and myometrium during the menstruial cycle and pregnancy. Virchoows Arch PatholAnat 1991, 419: 309-15 5. Brandon DD, Bethea CL, Strawn EY, et al Progesterone receptor messenger ribonucleic acid and protein are overexpresses in human uterine leiomyomas. Am ] Obstet Gynecol 1993; 169: 78- 85 6. Mittal K, Popiolek D, Demopoulos Rl. Uterine myxoid leiomyosarcoma within a leiomyoma. Human Pathol 2000; 31: 398-400 7. Scurry}, FRCPA, Hack M. Leiomyosarcoma arising in a lipoleiomyosarcoma. Gynecol Oncol 1990; 39: 381-3 8. Montague A, Swariz DP, Woodruff JD. Sarcoma arising in leiomyoma of uterus. Am J Obstet Gynecol 1965; 92: 421-7 9. Hendrickson MR, Kempson RL. Pure mesenchymal neoplasms of the uterine corpus. In; FoxH, Wells M. Eds. Obstetrical and Gynecological Pathology. Vol 1. 5th edn. Edinburg, London; Churchill Livingstone; 2003: 497-548 10. Carcangiu ML, Chambers JT, VaynickIM, Pino M, Schwartz PE. Immunhis to chemical evaluation of estrogen and progesterone receptor content in 183 patients with endometrial carcinoma. Part I: clinical and histologic correlations. Am J Clin Pathol 1990; 94: 247-54 11. Kounelis S, Kapranos N, Kouri E. Et al Immuno his to chemical profile of endometrial adenocarcinoma: astudy of 61 cases and review of the literature. Mod Pathol 2000; 13: 379-88 12. Pertschuk LP, Masood S, Simone J. et al Estrogen receptor immuno cytochemistry in endometrial carcinoma: a prognostic marker for survival. Gynecol Oncol 1996; 63: 28-33 13. Fukuda K, MoriM, Uchiyama M, IwaiK, Iwasaka T, Sugimori H. Prognostic significance of progesterone receptor immuno his to chemistry in endometrial carcinoma. Gynecol Oncol 1998; 69: 220-5 14. Sivridis E, GiatromanolakiA, Koukourakis M, Anastasiadis P. Endometrial carcinoma: association with low angiogenesis andbcl-2 expression. Vfrhows Arch 2001; 438: 470-7 15. IwaiK, Fukuda K, Hachisuga T. Etal. Prognostic signicanc