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Journals / Zeynep Kamil Tıp Bülteni / 2014 / Cilt: 45 - Sayı: 2

The Value of Acute Appendicitis Viewed 5-Hydroxy Indole Acetic Acid in Spot Urine

Spot İdrarda Bakılan 5-Hıdroksı İndol Asetık Asıtın Akut Apandısıt Tanılamasında Değeri

İnanç CİCİ
Ayşenur CELAYİR CERRAH
Vedat AKÇAER
Pages
94–99
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Sensitivity, specifity, positive predictive value and diagnostic specificity of 5-hydroxy indol acetic acid level in spot urine were 63%, 66%, 54%, 73%, respectively.Conclusion: Spot urine 5-hydroxy indol acetic acid levels in diagnosis of acute appendicitis seems to have limited diagnostic power as a single parameter in children

📌 3 Key Takeaways

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Objective & Hypothesis:Backgraund/Aim: This study is to investigate the significance of spot urine 5-hydroxy indol acetic acid levels in patients admitted with the suspicion of acute apendicitis.
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Key Findings & Data:Material/Method: Between January 2011 and June 2011, patients with the complaints of abdominal pain were evaluated according to levels of 5-hydroxy indol acetic acid in urine at admission.
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Conclusion & Impact:Sensitivity, specifity, positive predictive value and diagnostic specificity of 5-hydroxy indol acetic acid level in spot urine were 63%, 66%, 54%, 73%, respectively.Conclusion: Spot urine 5-hydroxy indol acetic acid levels in diagnosis of acute appendicitis seems to have limited diagnostic power as a single parameter in children
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Backgraund/Aim: This study is to investigate the significance of spot urine 5-hydroxy indol acetic acid levels in patients admitted with the suspicion of acute apendicitis. Material/Method: Between January 2011 and June 2011, patients with the complaints of abdominal pain were evaluated according to levels of 5-hydroxy indol acetic acid in urine at admission. This study was designed as prospectively. Results: Forthy-nine patients with the mean age of 10.4 years ±3.4 who were admitted and interned to our department during the one year period with the complaints of abdominal pain. After the clinical evaluation appendicitis was detected in 32 patients and abdominal pain was found to be due to causes other than appendicitis in 17 patients. Two of the patiens were negatif appendectomy. Spot urine samples were collected in all patients during admission and 5-hydroxy indol acetic acid levels were studied. The differences between the patients with acute appendicitis and other groups were not statistically significant (p>0.05). Sensitivity, specifity, positive predictive value and diagnostic specificity of 5-hydroxy indol acetic acid level in spot urine were 63%, 66%, 54%, 73%, respectively.Conclusion: Spot urine 5-hydroxy indol acetic acid levels in diagnosis of acute appendicitis seems to have limited diagnostic power as a single parameter in children

Özet

Amaç: Bu çalışma, akut apandisit şüphesi nedeniy-le acile başvuran hastalarda, idrarda bakılan 5-Hid-roksi İndol Asetik Asit seviyesinin tanı koymada an-lamlılığını değerlendirmektedir. Yöntem: 2011 Ocak- 2011 Aralık ayları arasında kli-niğimize karın ağrısı nedeniyle başvuran hastalarda idrarda 5-Hidroksi İndol Asetik Asit ileriye dönük ola-rak çalışma yapılmıştır.Sonuç: Bir yıllık sürede kliniğimize karın ağrısı ne-deniyle başvuran ve interne edilen, ortalama yaşları 10.4 yıl ±3.4 olan toplam 49 hastanın klinik değer-lendirme sonrası, 32 hastada apandisit, 17 hastada apandisit harici karın ağrısı tespit edilmiştir. Appen-dektomi yapılan 2 hastada apendiks normal ola-rak değerlendirilmiştir. Tüm başvuran hastalardan ilk başvuruda idrar örnekleri alınmıştır. Her 2 grup karşılaştırıldığında spot idrar 5-Hidroksi İndol Asetik Asit düzeyleri arasındaki fark istatistiksel olarak an-lamlı bulunmamıştır (p>0.05). Spot idrar 5-Hidroksi İndol Asetik Asit düzeylerinde özgüllük, duyarlılık, pozitif öngörü değeri, negatif öngörü değeri sırasıy-la %63, %66, %54 ve %73 olarak bulunmuştur. Karar: Spot idrar 5-Hidroksi İndol Asetik Asit değeri çocuklarda akut apandisit tanısında tek tip paramet-re olarak kullanıldığında sınırlı tanısal değeri olduğu saptanmıştır.

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Cite This Article

CİCİ, İ., CERRAH, A. C., AKÇAER, V. (2014). The Value of Acute Appendicitis Viewed 5-Hydroxy Indole Acetic Acid in Spot Urine. Zeynep Kamil Tıp Bülteni, Cilt: 45 - Sayı: 2, 94–99. https://ajindex.com/articles/335457

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