Journals / Üroonkoloji Bülteni / 2016 / Cilt: 15 - Sayı: 2

The Incidence of Prostate Adenocarcinoma in Patients Who Underwent Cystoprostatectomy for Invasive Baldder Cancer and Histopathological Examination

İnvaziv Üretelyal Mesane Kanseri Nedeniyle Sistoprostatektomi Yapılan Hastalarda Rastlantısal Prostat Kanseri Sıklığı ve Histopatolojik İncelemesi

Pages
61–64
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, prostate-sparing radical cystectomy techniques can be used as alternative surgical methods for younger and chosen patients to minimize continence and erectile problems and to improve the quality of life.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: It was aimed to evaluate the incidence of prostate adenocarcinoma in patients treated by cystoprostatectomy for invasive bladder urothelial carcinoma and to demonstrate the histopathological features of prostate cancer cases.
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Key Findings & Data:Materials and Methods: Between January 2010 and April 2015, totally 119 invasive bladder urothelial carcinoma patients operated by cystoprostatectomy without the diagnosis of prostate adenocarcinoma preoperatively were included into the study.
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Conclusion & Impact:Therefore, prostate-sparing radical cystectomy techniques can be used as alternative surgical methods for younger and chosen patients to minimize continence and erectile problems and to improve the quality of life.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: It was aimed to evaluate the incidence of prostate adenocarcinoma in patients treated by cystoprostatectomy for invasive bladder urothelial carcinoma and to demonstrate the histopathological features of prostate cancer cases. Materials and Methods: Between January 2010 and April 2015, totally 119 invasive bladder urothelial carcinoma patients operated by cystoprostatectomy without the diagnosis of prostate adenocarcinoma preoperatively were included into the study. The pathological records of patients were analyzed retrospectively. The patients were classified according to TNM system. Results: Prostate adenocarcinoma was detected in cystoprostatectomy materials of 16 patients (13.4%) and only 4 of the patients (25%) had clinically substantial prostate cancer. The average age was 62,3 (43-78, range) years. The pathological results of bladder urothelial carcinoma revealed as T2a in 4 (25%) patients, T2b in 4 (25%) patients, T3a in 6 (37.5%) patients and T4 only in 2 (12.5%) patients. Lymph node metastasis was detected in 5 (31.2%) patients and carcinoma in situ was detected in 5 (31.2%) patients. The mean follow-up time was 27.1 (4-63) months. The Gleason score of prostate cancer was 3+3 in 12 (75%) patients, 3+4 in 2 (12.5%) patient, 4+4 in 1 (6.25%) patient and 4+5 in 1 (6.25%) patient. The stages of prostate cancer were T2a in 14 (87.5%) patients, T2b in 1 (6.25%) patient and T3a in 1 (6.25%) patient. Conclusion: Life expectancy of the patients who had radical cystoprostatectomy due to invasive bladder tumor was affected dramatically by the pathological stage of urothelial carcinoma. Therefore, prostate-sparing radical cystectomy techniques can be used as alternative surgical methods for younger and chosen patients to minimize continence and erectile problems and to improve the quality of life.

Özet

Amaç: Bu çalışmada mesane ürotelyal kanseri nedeniyle radikal sistoprostatektomi yapılan hastalarda rastlantısal prostat adenokarsinomunun insidansını ve histopatolojik özelliklerini ortaya koymayı amaçladık. Gereç ve Yöntem: Ocak 2010 ve Nisan 2015 tarihleri arasında preoperatif prostat kanseri tanısı olmayan, invaziv mesane ürotelyal karsinomu nedeniyle sistoprostatektomi yapılan toplam 119 hasta çalışmaya dahil edildi. Hastaların patoloji raporları retrospektif olarak incelendi. Hastalar tümör nod metastaz sistemi ile sınıflandırıldı. Bulgular: Sistektomi materyallerinin 16'sında (%13,4) prostat adenokarsinomu saptandı ve bu hastaların yalnızca 4 (%25) tanesinde klinik açıdan önemli prostat kanseri mevcuttu. Ortalama yaş 62,3 (aralık 43-78) idi. Prostat kanserli hastaların Gleason skorları sırası ile 12 hastada (%75) 3+3, 2 hastada (%12,5) 3+4, 1 hastada (%6,25) 4+4 ve 1 hastada (%6,25) 4+5 idi. Prostat kanser evresi sırası ile 14 hastada (%87,5) T2a, 1 hastada (%6,25) T2b ve 1 hastada (%6,25) T3a idi. Mesane tümörü patolojik evreleri ise T2a 4 (%25) hasta, T2b 4 hasta (%25), T3a 6 hasta (%37) ve T4 2 hasta (%12,5) saptandı. Lenf nodu metastazı 5 hastada (%31,2) lenf nodu metastazı saptandı. Beş (%31,2) hastada karsinoma in situ saptandı. Ortalama takip süresi 27,1 (4-63) aydı. Sonuç: İnvaziv mesane tümörü nedeniyle radikal sistoprostatektomi yapılan hastaların yaşam beklentisi dramatik olarak mesane kanserinin patolojik evresinden dramatik olarak etkilenmektedir. Bu nedenle genç, seçilmiş hastalarda kontinans ve ereksiyon sorunlarını minimuma indirmek ve yaşam kalitesini artırmak için prostat koruyucu radikal sistektomi teknikleri alternatif cerrahi yöntemler olarak kullanılabilir.

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Cite This Article

CEYLAN, Y., ŞEN, V., POLAT, S., GÜNLÜSOY, B., DEĞİRMENCİ, T., TOPÇU, Y. K., BOLAT, D., KOZACIOĞLU, Z. (2016). The Incidence of Prostate Adenocarcinoma in Patients Who Underwent Cystoprostatectomy for Invasive Baldder Cancer and Histopathological Examination. Üroonkoloji Bülteni, Cilt: 15 - Sayı: 2, 61–64. https://ajindex.com/articles/334888

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