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Journals / Üroonkoloji Bülteni / 2017 / Cilt: 16 - Sayı: 3

Relationship Between Human Papilloma Virus and Bladder Cancer

İnsan Papilloma Virüsü ve Mesane Kanseri İlişkisi

Osman İNCİ
EBRU TAŞTEKİN
Hakan AKDERE
Pages
92–94
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the relationship between HPV-urothelial cancer and squamous cell carcinoma of the bladder is examined with references to the literature

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Human papilloma virus (HPV) is a DNA virus with more than 170 types.
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Key Findings & Data:HPV is the most common sexually transmitted infection and 10% of the world’s cancer burden is thought to be HPV infection-related.
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Conclusion & Impact:In this review, the relationship between HPV-urothelial cancer and squamous cell carcinoma of the bladder is examined with references to the literature
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Human papilloma virus (HPV) is a DNA virus with more than 170 types. HPV is the most common sexually transmitted infection and 10% of the world’s cancer burden is thought to be HPV infection-related. It is known that precancerous lesions caused by some subgroups of this virus transformed into invasive carcinoma, and its place in etiology of cervix, vulva, oropharynx, anus and penile cancer is also well-known. Cases have been published where condyloma are seen not only in anogenital region, but also in urethra, bladder and ureter. However, their role in bladder cancer pathogenesis is questionable. Recent studies showed that HPV and bladder cancer are associated. Condyloma was identified to be in the development of squamous cell carcinoma of the bladder. In this review, the relationship between HPV-urothelial cancer and squamous cell carcinoma of the bladder is examined with references to the literature

Özet

İnsan papilloma virüsü (HPV), 170'ten fazla tipi bulunan bir DNA virüsüdür. HPV cinsel bulaşan enfeksiyonlar arasında en yaygın olanıdır ve dünya kanser yükünün %10 kadarının HPV enfeksiyonuna bağlı olduğu sanılmaktadır. Virüsün bazı subgruplarının yaptığı prekanseröz lezyonların invaziv karsinomlara dönüştüğü, serviks, vulva, orofarenks, anüs ve penis kanser etiyolojisindeki yeri bilinmektedir. Anogenital bölgede gözlenen kondilomların üretra, mesane ve üreterde de görüldüğü olgular yayınlanmıştır. Mesane kanseri patogenezindeki yeri ise tartışmalıdır. Yapılan son çalışmalar HPV ile mesane kanseri arasında ilişki olduğunu göstermektedir. Mesanenin skuamöz hücreli karsinomlarının zemininde kondilomların varlığı gösterilmiştir. Bu derlemede literatür eşliğinde HPV-ürotelyal karsinom ve mesanenin skuamöz hücreli karsinomu ilişkisi değerlendirilmeye çalışıldı.

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Cite This Article

İNCİ, O., TAŞTEKİN, E., AKDERE, H. (2017). Relationship Between Human Papilloma Virus and Bladder Cancer. Üroonkoloji Bülteni, Cilt: 16 - Sayı: 3, 92–94. https://ajindex.com/articles/334886

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References (14)

  1. Blochin EB, Park KJ, Tickoo SK, et al. Urothelial carcinoma with prominent squamous differentiation in the setting of neurogenic bladder: role of human papillomavirus infection. Mod Pathol 25:1534-1542
  2. Li N, Yang L, Zhang Y, et al. Human papillomavirus infection and bladder cancer risk: a meta-analysis. J Infect Dis 2011;204:217-223
  3. Anwar K, Naiki H, Nakakuki K, Inuzuka M. High frequency of human papillomavirus infection in carcinoma of the urinary bladder. Cancer 1992;70:1967-1973
  4. Stanley MA, Winder DM, Sterling JC, Goon PK. HPV infection, anal intra-epithelial neoplasia (AIN) and anal cancer: current issues. BMC Cancer 2012;12:398. 5. “Human papillomavirus (HPV)”. World Health Organization. April 13, 2015. Retrieved 2015-07-06
  5. Goldstein MA, Goodman A, del Carmen MG, Wilbur DC. Case records of the Massachusetts General Hospital. Case 10-2009. A 23-year-old woman with an abnormal Papanicolaou smear. N Engl J Med 2009;360:1337-1344
  6. Javier RT, Butel JS. The history of tumor virology. Cancer Res 2008;68:7693-7706
  7. Hoory T, Monie A, Grawitt P, Wu TC. Molecular epidemiology of human papillomavirus. J Formos Med Assoc 2008;107:198-217
  8. Chaturvedi Anil, Gillison ML. Human Papillomavirus and Head and Neck Cancer. In: Olshan AF. Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer 1st ed. New York: Springer; 2010. p. 1471-1472
  9. Motoyama S, Ladines-Llave CA, Luis Villanueva S, Maruo T. The role of human papilloma virus in the molecular biology of cervical carcinogenesis. Kobe J Med Sci 2004;50:9-19
  10. Walboomers JM, Jacobs MV, Manos MM, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 1999;189:12-19
  11. Kurman RJ, Ronnett BM, Sherman ME, Wilkinson EJ. Human papillomavirus: biology and clinical importance. In: Tumors of the Cervix, Vagina, and Vulva. AFIP Atlas of Tumor Pathology. 4th ed. series. Silver Spring, MD: ARP Press; 2010. p. 23-58
  12. Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 2010;14:24-35
  13. Rubin MA, Kleter B, Zhou M, et al. Detection and typing of human papillomavirus DNA in penile carcinoma: evidence for multiple independent pathways of penile carcinogenesis. Am J Pathol 2001;159:1211-1218
  14. Buitrago-Perez A, Garaulet G, Vazquez-Carballo A, et al. Molecular signature of HPV-Induced carcinogenesis: pRb, p53 and Gene Expression Profiling. Curr Genomics 2009;10:26-34