Journals / Van Tıp Dergisi / 2018 / Cilt: 25 - Sayı: 3

Retrospective Analysis of Patients Admitted To Our Pediatrics Outpatient Clinic Between 2011 and 2015 With A Complaint of Diarrhea With Adenovirus and/or Rotavirus Positivity

2011-2015 Yılları Arasında Üniversitemiz Çocuk Polikliniklerine Ishal Şikâyeti Ile Başvuran ve Adenovirüs ve/veya Rotavirüs Pozitifliği Saptanan Hastaların Retrospektif Değerlendirilmesi

Pages
374–380
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Based on our study results, we believe that patients with viral gastroenteritis caused by rotavirus and/or adenovirus should be monitored for the development of secondary infections, considering urea, albumin levels, white blood cells, and CRP values.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Childhood diarrheas are mostly caused by viruses.
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Key Findings & Data:Materials and Methods: A total of 259 children were included in the study, and the patients were divided into two groups: patient group (n = 129) and control group (n = 130).
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Conclusion & Impact:Conclusion: Based on our study results, we believe that patients with viral gastroenteritis caused by rotavirus and/or adenovirus should be monitored for the development of secondary infections, considering urea, albumin levels, white blood cells, and CRP values.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Childhood diarrheas are mostly caused by viruses. Enteric viruses (particularly rotavirus and adenovirus) are the most common culprits of acute gastroenteritis. Materials and Methods: A total of 259 children were included in the study, and the patients were divided into two groups: patient group (n = 129) and control group (n = 130). The study group was also sub-divided in three as rotavirus positivity, adenovirus positivity, and both rotavirus + adenovirus positivity. Results: The mean age of the patient group was 21.7 ± 30.0 months, and 60.5% were males. While the presence of diarrhea (p = 0.023) and the number of diarrhea between 0 and 10 (p = 0.001) were statistically higher in the control group, the number of diarrhea between 11 and 15 was statistically highe r in the patient group. Rotavirus was positive for 71.3%, adenovirus was positive for 20.2%, both rotavirus + adenovirus were positive for 8.5% in the patient group. There was a statistically strong and significant relation with white blood cell, urea, albumin and C-reactive protein (CRP) values for the patients with rotavirus positivity (p < 0.05). There was a statistically strong and significant relation with diarrhea, vomiting, abdominal pain, and lack of appetite for both three subgroups with rotavirus positivity, adenovirus positivity, and both rotavirus + adenovirus positivity (p < 0.05). Conclusion: Based on our study results, we believe that patients with viral gastroenteritis caused by rotavirus and/or adenovirus should be monitored for the development of secondary infections, considering urea, albumin levels, white blood cells, and CRP values.

Özet

Amaç: Çocukluk çağı ishalleri sıklıkla virüslerden kaynaklanır. Enterik virüsler (özellikle rotavirüs ve adenovirüs) bakteriyel olmayan akut gastroenteritlerin en sık nedeni olarak bildirilmiştir. Gereç ve Yöntem: Çalışmaya 129 hasta ve 130 kontrol grubu olmak üzere toplam 259 çocuk dâhil edildi. Çalışma grubundaki vakalar rotavirüs pozitif, adenovirüs pozitif ve hem rotavirüs hem de adenovirüs pozitif olmak üzere üç gruba ayrıldı. Bulgular: Çalışma grubundaki olguların yaş ortalamaları 21,7 ± 30,0 ay ve %60,5’i erkek idi. Kontrol grubundaki vakalarda ishal varlığı (p = 0,023) ve 0-10 arasındaki ishal sayısı (p = 0,001) istatistiksel olarak daha yüksek iken, çalışma grubunda 11 -15 arasındaki ishal sayısı (p = 0,001) çalışma grubunda daha fazla idi. Çalışma grubundaki olguların %71,3’ünde rotavirüs, %20,2’sinde adenovirüs ve %8,5’inde hem rotavirüs hem de adenovirüs antijen pozitifliği vardı. Rotavirüs pozitif gruptaki hastaların üre, albümin ve CRP değerleri arasında istatistiksel yönden kuvvetli ve anlamlı bir ilişki varken, Adenovirüs ve hem Rotavirüs hem de Adenovirüs pozitif gruptaki hastaların beyaz küre sayısı, üre, albümin ve CRP değerleri arasında istatistiksel yönden kuvvetli ve anlamlı bir ilişki vardı (p < 0,05). Rotavirüs pozitif, adenovirüs pozitif ve hem rotavirüs hem de adenovirüs pozitif olan üç gruptaki vakalarda ishal, kusma, karın ağrısı ve iştahsızlık ile aralarında istatistiksel yönden kuvvetli ve anlamlı bir ilişki vardı (p < 0,05). Sonuç: Özellikle viral gastroenteritlerden rotavirüs ve/veya adenovirüs enfeksiyonunda üre ve albumin ile sekonder enfeksiyon açısından beyaz küre sayısı ve CRP düzeylerinin de yakın takip edilmesi gerektiği kanısındayız.

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Cite This Article

ÇUBUK, E., AKTAR, F., YILMAZ, K., SABAZ, M. N., SOLMAZ, M., ASENA, M., DEVECİOĞLU, M. C. (2018). Retrospective Analysis of Patients Admitted To Our Pediatrics Outpatient Clinic Between 2011 and 2015 With A Complaint of Diarrhea With Adenovirus and/or Rotavirus Positivity. Van Tıp Dergisi, Cilt: 25 - Sayı: 3, 374–380. https://ajindex.com/articles/334831

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References (10)

  1. Koletzko S, Osterrieder S. Acute infectious diarrhea in children. Dtsch Arztebl Int 2009; 106(33): 539-547.
  2. Liu L, Johnson HL, Cousens S, Perin J, Scott S, Lawn JE, et al. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet 2012; 379(9832): 2151-2161.
  3. Gül M, Garipardıç M, Çırağil P, Aral M, Karabiber H, Güler İ. 0-5 yaş arası gastroenteritli çocuklarda rotavirüs ve adenovirüs tip 40/41 araştırılması. ANKEM Der 2005; 19: 64-67.
  4. Mete E, Akelma AZ, Cizmeci MN, Bozkaya D, Kanburoglu MK. Decreased mean platelet volume in children with acute rotavirus gastroenteritis. Platelets 2014; 25(1): 51-54.
  5. Dalgıç N, Haşim Ö, Pullu M, Sancar M, Kafadar İ, Yılmaz A. Is rotavirus diarrhea a systemic viral infection? Çocuk Enf Derg 2010; 4: 48-55.
  6. Bozdayi G, Dogan B, Dalgic B, Bostanci I, Sari S, Battaloglu NO, et al. Diversity of human rotavirus G9 among children in Turkey. J Med Virol 2008; 80(4): 733-740.
  7. Akdoğan D, Çınar S, Şahin İ, Per H, Kılıç H. 0-5 yaş çocuk ishallerinde rotavirüs araştırılması. İnfek Derg 2001; 15: 291-294.
  8. Kurugöl Z, Geylani S, Karaca Y, Umay F, Erensoy S, Vardar F, et al. Rotavirüs gastroenteritis among children among five years of age in İzmir, Turkey. Turk J Pediatr 2003; 45(4): 290-294.
  9. Albano F, Bruzzese E, Bella A, Cascio A, Titone L, Arista S, et al. Rotavirus and not age determines gastroenteritis severity in children: a hospital-based study. Eur J Pediatr 2007; 166(3): 241-247.
  10. Colomba C, De Grazia S, Giammanco GM, Saporito L, Scarlata F, Titone L, et al. Viral gastroenteritis in children hospitalised in Sicily, Italy. Eur J Clin Microbiol Infect Dis 2006; 25(9): 570-575. López-de-Andrés A, Jiménez-García R, Carrasco- Garrido P, Alvaro-Meca A, Galarza PG, de Miguel AG. Hospitalizations associated with rotavirus gastroenteritis in Spain, 2001-2005. BMC Public Health 2008; 8: 109. Staat MA, Azimi PH, Berke T, Roberts N, Bernstein DI, Ward RL, et al. Clinical presentation of rotavirüs infection among hospitalized children. Pediatr Infect Dis J 2002; 21(3): 221-227. Román E, Wilhelmi I, Colomina J, Villar J, Cilleruelo ML, Nebreda V, et al. Acute viral gastroenteritis: proportion and clinical relevance of multiple infections in Spanish children. J Med Microbiol 2003; 52(5): 435-440. Rodrigues A, de Carvalho M, Monteiro S, Mikkelsen CS, Aaby P, Molbak K, et al. Hospital surveillance of rotavirus infection and nosocomial transmission of rotavirus disease among chil