Journals / Van Tıp Dergisi / 2019 / Cilt: 26 - Sayı: 4

The relationship between vitamin D deficiency and deep vein thrombosis

D Vitamini Eksikliğiyle Derin Ven Trombozu Arasındaki İlişki

Pages
526–531
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Furthermore, the coexistence of thrombophilic risk factors and vitamin D deficiency is likely to increase the risk of DVT.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Vitamin D is a fat-soluble vitamin that plays a role in calcium and phosphorus metabolism.
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Key Findings & Data:Materials and Methods: This study was performed between December 2015 and December 2018.
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Conclusion & Impact:Furthermore, the coexistence of thrombophilic risk factors and vitamin D deficiency is likely to increase the risk of DVT.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: Vitamin D is a fat-soluble vitamin that plays a role in calcium and phosphorus metabolism. Deep vein thrombosis (DVT) is an important health problem worldwide. Some researchers have reported that vitamin D supplementation reduces the risk of venous thromboembolism. The aim of our study was to evaluate vitamin D levels in patients with DVT. Materials and Methods: This study was performed between December 2015 and December 2018. Vitamin D level measured patients during December, January, February and March were included in the study. Serum D 25 (OH) D (25- hydroxyvitamin) levels were measured to evaluate vitamin D levels of the patients. Results: Our study included 58 patients with DVT whose vitamin D levels were measured. There were 27 females and 31 males, ranging in age from 15 to 85 years with a mean age of 55.8 ± -17.3 years. Vitamin D deficiency was found in 50 patients and vitamin D insufficiency found in 7 patients. The mean vitamin D level was 12.7 ± 5.0 ng / mL in male patients and 12.1 ± 7.3 ng / mL in female patients. There was no significant difference between the mean vitamin D levels of women and men (p> 0.05). Conclusion: In our study, 25 (OH) D levels were found to be lower in both male and female patients with DVT. This is in line with some studies describing vitamin D deficiency as a risk factor for venous thrombosis. Furthermore, the coexistence of thrombophilic risk factors and vitamin D deficiency is likely to increase the risk of DVT.

Özet

Amaç: D Vitamini, kalsiyum ve fosfor metabolizmasında rol oynayan, yağda çözünen bir vitamindir. Derin ven trombozu (DVT) dünya çapında önemli bir sağlık sorunudur. Bazı araştırıcılar D vitamini takviyesinin venöz tromboembolizm riskini azalttığını bildirmiştir. Çalışmamızın amacı DVT’li hastalarda vitamin D düzeyinin değerlendirilmesidir. Gereç ve Yöntem: Bu çalışma, Aralık 2015-Aralık 2018 tarihleri arasında yapıldı. Aralık, Ocak, Şubat ve mart aylarında vitamin D seviyeleri ölçülen hastalar çalışma kapsamına alındı. Hastaların D vitamini düzeylerinin değerlendirmek için serum D 25 (OH) D (25-hidroksivitamin) düzeyleri ölçüldü. Bulgular: Çalışmamız vitamin D seviyeleri ölçülen ve DVT tanısı konulan 58 hastayı kapsamaktadır. Hastaların 27’si kadın ve 31’i erkek idi ve yaşları 15 ile 85 arasında değişmekteydi ve ortalama yaş ise 55.8±-17.3 yıl idi. Hastaların 50’sinde vitamin D eksikliği, 7’sinde vitamin D yetersizliği tespit edildi. Ortalama vitamin D düzeyi erkek hastalarda 12.7±5.0 ng/mL ve kadın hastalardaysa 12.1±7.3 ng/mL idi. Kadın ve erkek hastaların ortalama vitamin D düzeyleri arasında anlamlı bir fark yoktu (p>0.05). Sonuç: Çalışmamızda DVT olan hem erkek hem kadın hastalarda 25 (OH) D düzeyinin düşük olduğu görülmüştür. Bu da, D vitamini eksikliğinin venöz tromboz için bir risk faktörü olarak tanımlayan bazı çalışmalarla uyumludur. Ayrıca, trombofilik risk faktörlerinin ve D vitamini eksikliğinin birlikteliğinin, DVT riskini daha da arttırması muhtemeldir.

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Cite This Article

EKİM, M., EKİM, H. (2019). The relationship between vitamin D deficiency and deep vein thrombosis. Van Tıp Dergisi, Cilt: 26 - Sayı: 4, 526–531. https://ajindex.com/articles/334673

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