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Journals / Van Tıp Dergisi / 2000 / Cilt: 7 - Sayı: 2

An analytical approach to PSA: Correlation of fPSA with other variables in various age and prostate volume subgroups

PSA'ya analitik yaklaşım: Farklı yaş grupları ve prostat hacimlerinde diğer değişkenlerle sPSA'nın bağıntısının incelenmesi

Sabahattin AYDIN
Gökmen Alp DOĞDU
Yüksel YILMAZ
Mustafa K. ATİLLA
Öner ODABAŞ
Pages
46–50
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Free PSA was found to be relatively influenced by volume, tPSA, cPSA and PSAD, but this influence showed differences in various value ranges

📌 3 Key Takeaways

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Objective & Hypothesis:Effects of various parameters related to prostate gland, such as age, volume, total prostate specific antigen (PSA), complex PSA (cPSA), free/total PSA (f/t PSA) and PSA density (PSAD) on free PSA (fPSA) activity was investigated by comparing the correlation coefficients of these variables in various ranges of age and prostate volume.
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Key Findings & Data:Hundred and nine consequative patients with the complaints of prostatism comprised the study after having undergone digital rectal examination and transrectal ultrasonography to rule out prostate cancer.
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Conclusion & Impact:Free PSA was found to be relatively influenced by volume, tPSA, cPSA and PSAD, but this influence showed differences in various value ranges
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hidrojen-iyon konsantrasyonu · İstatistik · Yaş faktörü

Abstract

Effects of various parameters related to prostate gland, such as age, volume, total prostate specific antigen (PSA), complex PSA (cPSA), free/total PSA (f/t PSA) and PSA density (PSAD) on free PSA (fPSA) activity was investigated by comparing the correlation coefficients of these variables in various ranges of age and prostate volume. Hundred and nine consequative patients with the complaints of prostatism comprised the study after having undergone digital rectal examination and transrectal ultrasonography to rule out prostate cancer. Free PSA was found to be relatively influenced by volume, tPSA, cPSA and PSAD, but this influence showed differences in various value ranges

Özet

Farklı yaş ve prostat hacmi (PH) alt gruplarında yaş, PH, total prostat spesifik antijen (tPSA), bağlı PSA (bPSA), serbest/total PSA (s/t PSA) ve PSA dansitesi (PSAD) gibi prostat bezi ile ilintili olan parametrelerin, serbest PSA (sPSA) düzeyine etkisini araştırmak amacıyla korelasyon analizleri yapılmıştır. Prostatizm şikayeti ile başvuran 109 hasta prostat kanserini ekarte etmek için parmakla rektal muayene ve transrektal ultrasonografik incelemeden sonra çalışmaya alındı. Serbest PSA ile PH, tPSA, bPSA ve PSAD arasında bağıntı olduğu, ancak yaş ve PH'nin farklı alt gruplarında bu etkileşimin değişiklikler gösterdiği saptandı.

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Cite This Article

AYDIN, S., DOĞDU, G. A., YILMAZ, Y., ATİLLA, M. K., ODABAŞ, Ö. (2000). An analytical approach to PSA: Correlation of fPSA with other variables in various age and prostate volume subgroups. Van Tıp Dergisi, Cilt: 7 - Sayı: 2, 46–50. https://ajindex.com/articles/334666

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