Journals / Van Tıp Dergisi / 2020 / Cilt: 27 - Sayı: 2

Evaluation of Orbital Blood Flow in Age-Related Macular Degeneration by Color Doppler Ultrasonography

Yaşa Bağlı Makula Dejeneresansında Orbital Kan Akımının Renkli Doppler Ultrasonografi ile Değerlendirilmesi

Pages
177–183
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, further studies are required to obtain a place for DUSG to detect orbital blood flow disorder in patients with AMD.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim in this study was to evaluate the ocular blood flow in patients with age-related macular degeneration (AMD) using Doppler-ultrasonography ( Material and Methods: This study included the AMD patients from Ophthalmology Department of Dicle University Medical Faculty.
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Key Findings & Data:The mean peak-systolic-velocity (PSV), enddiastolic-velocity (EDV), resistivity-index (RI) values of the posterior ciliary artery (PSA), central retinal artery (CRA) and ophthalmic artery (OA) were measured with DUSG Results: There were 39 patients over 50 years of age.
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Conclusion & Impact:However, further studies are required to obtain a place for DUSG to detect orbital blood flow disorder in patients with AMD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim in this study was to evaluate the ocular blood flow in patients with age-related macular degeneration (AMD) using Doppler-ultrasonography ( Material and Methods: This study included the AMD patients from Ophthalmology Department of Dicle University Medical Faculty. Visual acuity, intraocular pressure, anterior and posterior segment examination were performed. The mean peak-systolic-velocity (PSV), enddiastolic-velocity (EDV), resistivity-index (RI) values of the posterior ciliary artery (PSA), central retinal artery (CRA) and ophthalmic artery (OA) were measured with DUSG Results: There were 39 patients over 50 years of age. Of 39 patients, 15 (38.46%) were female and 24 (61.54%) were male. The mean age was 72.2 ± 8.3 years. There was no statistically significant difference in PSV, EDV and RI values between the eyes with and without AMD (p>0.05). In 11 patients AMD was unilateral. There was no statistically significant difference between the eyes in those patients in terms of mean PSV, EDV and RI values of OA, SRA and PCA (p>0.05). There was a statistically significant difference between the mean RI values of PCA and SRA in cases with neovascular-AMD and nonneovascular-AMD (p<0.05). A statistically significant difference was found between the mean EDV and PSV values of PCA with eyes in patients with HT and in patients without HT (p<0.05). Conclusions: The increase in vascular resistance and the decrease in orbital blood flow were shown by DUSG in patients with neovascular-AMD. However, further studies are required to obtain a place for DUSG to detect orbital blood flow disorder in patients with AMD.

Özet

Amaç: Bu çalışmada yaşa bağlı maküla dejenerasyonu (YBMD) hastalarının renkli doppler ultrasonografi (RDUSG) kullanarak oküle r kan akımlarının değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Dicle Üniversitesi Tıp Fakültesi Göz Hastalıkları kliniğinde YBMD tanılı hastalar çalışmaya dâhil edildi. Görme keskinliği ve göz içi basıncı ölçümleri ile ön ve arka segment muayenesi yap ılarak bulgular kaydedildi. RDUSG ile posterior silier arter (PSA), santral retinal arter (SRA) ve oftalmik arter (OA) ortalama sistolik zirve hızı (PSV), end diastolik hız (EDV) ve rezistivite özdirenç indeksi (RI) değerleri ölçüldü. Bulgular: YBMD tanısı yla takipleri bulunan 50 yaş üzerindeki 39 hasta çalışmaya alındı. 39 hastanın 15’i kadın (%38.46), 24’ü erkek (%61.54) idi. Ortalama yaş 72.2 ± 8.3 idi. YBMD olan ve olmayan gözler arasında her üç artere ait PSV, EDV ve RI değerleri bakımından istatistik sel olarak anlamlı fark izlenmedi (p>0.05). İstatistiksel açıdan bir gözünde YBMD olan ve diğer gözünde YBMD olmayan 11 hastada OA, SRA, PSA’ya ait ortalama PSV, EDV, RI değerleri bakımından gözler arasında anlamlı fark izlenmedi (p>0.05). Neovasküler YBMD olan olgular ile kuru tipYBMD olan olgular arasında PCA ve SRA’ya ait ortalama RI değerleri arasında istatistiksel olarak anlamlı fark bulundu (p<0.05). İstatistiksel açıdan HT’si olan YBMD’li gözler ile HT’si olmayan YBMD’li gözler arasında PCA’ya ait or talama EDV ve PSV değerleri arasında anlamlı fark bulundu (p< Sonuç: Çalışmamızda neovasküler tip YBMD hastalarında oküler kan akımında azalma ve direnç artışı RDUSG ile gösterilmiştir. Ancak YBMD hastalarında oküler kan akımı bozukluğunun saptanması nda RDUSG’nin bir yer edinebilmesi için geniş seri çalışmaları gerekmektedir.

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Cite This Article

KARAHAN, M., Kılıç, D., DURSUN, M. E., DURSUN, B., UĞURLU, A., AVA, S., ERDEM, S., KEKLİKÇİ, U., ŞAKALAR, Y. B. (2020). Evaluation of Orbital Blood Flow in Age-Related Macular Degeneration by Color Doppler Ultrasonography. Van Tıp Dergisi, Cilt: 27 - Sayı: 2, 177–183. https://ajindex.com/articles/334482

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