Journals / Üroonkoloji Bülteni / 2016 / Cilt: 15 - Sayı: 1

Transrektal Ultrason Klavuzluğunda Yapılan Prostat Biyopsisinde Uygulanan Periprostatik Sinir Blokajında Uygun Prilokain Dozu: Doz Hesaplamada Yeni Bir Yaklaşım

The Optimum Dosage of Prilocaine in Periprostatic Nerve Block During Transrectal Ultrasound Guided Prostate Biopsy: A New Approach in Dose Calculation

Pages
13–17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: It was found that VAS scores of patients were significantly positive correlated with prostatic volume, Size 1, 2 and 3 (p<0.05).

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to calculate the optimum dose of prilocaine per one mL prostate volume in periprostatic nerve block (PPNB) during transrectal ultrasound (TRUS) guided prostate biopsy (PBx).
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Key Findings & Data:Materials and Methods: We retrospectively evaluated the medical records of 83 patients from whom 12 cores TRUS guided PBx were obtained between years 2011 and 2013.
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Conclusion & Impact:Results: It was found that VAS scores of patients were significantly positive correlated with prostatic volume, Size 1, 2 and 3 (p<0.05).
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to calculate the optimum dose of prilocaine per one mL prostate volume in periprostatic nerve block (PPNB) during transrectal ultrasound (TRUS) guided prostate biopsy (PBx). Materials and Methods: We retrospectively evaluated the medical records of 83 patients from whom 12 cores TRUS guided PBx were obtained between years 2011 and 2013. Prostatic sizes were evaluated separately as Size 1 (anterior-posterior on the axial plane), Size 2 (transversal), and Size 3 (cranial-caudal on the sagittal plane) for all patients. The visual analog scores (VAS) of the patients during PBx, prostatic volumes, and prilocaine doses per one mL prostate were evaluated. The correlation between VAS of patients during PBx and prostatic volume, the prostatic sizes and prilocaine dosage per one mL prostate was analyzed using Cubic regression test. Results: It was found that VAS scores of patients were significantly positive correlated with prostatic volume, Size 1, 2 and 3 (p<0.05). However, there was a negative significant correlation between VAS and prilocaine dose per one mL prostate volume (r=-0.402, p<0.01). The dose of 0.1 mL prilocaine infiltration per one mL prostatic tissue in PPNB was the maximum dose that caused a mild and under annoying pain (VAS<2) in patients according to cubic regression formula. Conclusion: Prilocaine dosage, prostatic volume and prostatic sizes (especially anterior-posterior and cranial-caudal) significantly affect VAS scores during TRUS guided PBx. The pain in TRUS guided PBx should be controlled with an optimum dose of prilocaine as 0.1 mL per one mL of prostatic tissue.

Özet

Amaç: Amacımız transrektal ultrason (TRUS) kılavuzluğunda yapılan prostat biyopsisinde (PB) uygulanan periprostatik sinir blokajında (PPSB) prostat hacmi başına en uygun prilokain dozunun hesaplanmasıdır. Gereç ve Yöntem: 2011-2013 yılları arasında 12 kor TRUS kılavuzluğunda PB alınan 83 hastanın tıbbi kayıtları geriye dönük incelendi. Prostat boyutu, aksiyel planda antero-posterior (Boyut 1) ve transvers ölçüm (Boyut 2) ve sagittal planda kraniyo-kaudal ölçüm (Boyut 3) kullanılarak hesaplandı. TRUS-PB esnasındaki visual analog skala (VAS), prostat hacimleri ve 1 ml prostat hacmi başına uygulanan prilokain dozu değerlendirildi. Hastaların VAS ile prostat hacimleri, prostat boyutları ve uygulanan prilokain dozları arasındaki korelasyon Cubic regresyon testi ile hesaplandı. Bulgular: VAS ile prostat boyut 1, 2, 3 ve prostat hacmi arasında anlamlı olarak pozitif korelasyon mevcuttur (p<0,05). Ancak VAS ile 1 ml prostat hacmi başına prilokain dozu arasında anlamlı olarak negatif korelasyon mevcuttur (r=-0,402, p<0,01). Kübik regresyon formülüne göre TRUS kılavuzluğunda PB sırasında hafif ve rahatsız etmeyen ağrı düzeyi (VAS<2) için PPSB sırasında yapılması gereken maksimum prilokain dozu 1 ml prostat hacmi başına 0,1 ml prilokain infiltrasyonudur. Sonuç: TRUS kılavuzluğunda PB sırasında saptanan VAS, prilokain dozu, prostat hacmi ve özellikle antero-prosterior ve kraniyo-kaudal prostat boyutlarından anlamlı olarak etkilenmektedir. TURS kılavuzluğunda PB esnasındaki ağrı 1 ml prostat dokusu başına 0,1 ml prilokain dozu ile etkin olarak kontrol edilebilmektedir.

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Cite This Article

GÖNÜLALAN, U., KOŞAN, M., KERVANCIOĞLU, E., ÇİÇEK, T., ÖZTÜRK, B., ÖZKARDEŞ, H. (2016). Transrektal Ultrason Klavuzluğunda Yapılan Prostat Biyopsisinde Uygulanan Periprostatik Sinir Blokajında Uygun Prilokain Dozu: Doz Hesaplamada Yeni Bir Yaklaşım. Üroonkoloji Bülteni, Cilt: 15 - Sayı: 1, 13–17. https://ajindex.com/articles/334441

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